ListarInstituto de Investigación Biomédica da Coruña (INIBIC) por tema "Therapeutics"

Mostrando ítems 1-3 de 3

    • Clinical-pathological characteristics and prognosis of a cohort of oesophageal cancer patients: a competing risks survival analysis 

      Rodríguez-Camacho, Elena; Pita-Fernández, Salvador; López-Calviño, Beatriz; Pértega-Díaz, Sonia; Seoane-Pillado, Teresa (Japan Epidemiological Association, 2015-01-19)
      [Abstract] Background: To determine the clinical course, follow-up strategies, and survival of oesophageal cancer patients using a competing risks survival analysis. Methods: We conducted a retrospective and prospective ...

    • Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy 

      Nogueira Recalde, Uxía; Lorenzo Gómez, Irene; Blanco García, Francisco J; Loza, María Isabel; Grassi, Diego; Shirinsky, Valery; Shirinsky, Ivan; Lotz, Martin; Robbins, Paul D.; Domínguez, Eduardo; Caramés, Beatriz (Elsevier, 2019-07-05)
      [Abstract] Background. Ageing-related failure of homeostasis mechanisms contributes to articular cartilage degeneration and osteoarthritis (OA), for which disease-modifying treatments are not available. Our objective was ...

    • Neuropathic Pain in the IMI-APPROACH Knee Osteoarthritis Cohort: Prevalence and Phenotyping 

      van Helvoort, Eefje M.; Welsing, Paco M.J.; Jansen, Mylène P.; Gielis, Willem Paul; Loef, Marieke; Kloppenburg, Margreet; Blanco García, Francisco J; Haugen, Ida K.; Berenbaum, Francis; Bay-Jensen, Anne-C; Ladel, Christoph H.; Lalande, Agnes; Larkin, Jonathan; Loughlin, John; Mobasheri, Ali; Weinans, Harrie; Lafeber, Floris; Eijkelkamp, Niels; Mastbergen, Simon (BMJ, 2021-12-15)
      [Abstract] Objectives: Osteoarthritis (OA) patients with a neuropathic pain (NP) component may represent a specific phenotype. This study compares joint damage, pain and functional disability between knee OA patients with ...