ListarInstituto de Investigación Biomédica da Coruña (INIBIC) por tema "Proteoglycans"
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Extracellular Matrix in Heart Failure: Role of ADAMTS5 in Proteoglycan Remodeling
(American Heart Association, 2021-11-22)[Abstract] Background: Remodeling of the extracellular matrix (ECM) is a hallmark of heart failure (HF). Our previous analysis of the secretome of murine cardiac fibroblasts returned ADAMTS5 (a disintegrin and metalloproteinase ... -
Long-term effects of hydrogen sulfide on the anabolic-catabolic balance of articular cartilage in vitro
(Elsevier, 2017-08-15)[Abstract] Healthy cartilage maintenance relies on an equilibrium among the anabolic and catabolic processes in chondrocytes. With the onset of osteoarthritis (OA), increased interleukin (IL)-1β levels induce an inhibition ... -
Mitochondrial Respiratory Chain Dysfunction Modulates Metalloproteases -1, -3 and -13 in Human Normal Chondrocytes in Culture
(BioMed Central, 2013-08-09)[Abstract] Background. Mitochondrion has an important role in the osteoarthritis (OA) pathology. We have previously demonstrated that the alteration of the mitochondrial respiratory chain (MRC) contributes to the inflammatory ...