• Design of a digital-PCR assay to quantify fragmented human mitochondrial DNA 

      Mosquera, Alejandro; Guillén, Rebeca; Otero, Fátima; Rego-Pérez, Ignacio; Blanco García, Francisco J; Fernández, José Luis (Wiley, 2021-06-11)
      [Abstract] Digital PCR (dPCR) has been adapted to quantify the proportion of mitochondrial DNA (mtDNA) molecules without and with double-strand DNA breaks (DSBs). This is based on a break-apart approach of two differentially ...