Listar Instituto de Investigación Biomédica da Coruña (INIBIC) por autor "Cadeiras, Martin"
Mostrando ítems 1-3 de 3
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An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms
Parkes, Michael D.; Aliabadi, Arezu Z.; Cadeiras, Martin; Crespo-Leiro, María Generosa; Deng, Mario; Depasquale, Eugene C.; Goekler, Johannes; Kim, Daniel H.; Kobashigawa, Jon; Loupy, Alexandre; Macdonald, Peter; Potena, Luciano; Zuckermann, Andreas; Halloran, Philip F. (Elsevier, 2019-02-06)[Abstract] BACKGROUND. We previously reported a microarray-based diagnostic system for heart transplant endomyocardial biopsies (EMBs), using either 3-archetype (3AA) or 4-archetype (4AA) unsupervised algorithms to estimate ... -
Assessing the relationship between molecular rejection and parenchymal injury in heart transplant biopsies
Madill-Thomsen, Katelynn S.; Reeve, Jeff; Aliabadi-Zuckermann, Arezu; Cadeiras, Martin; Crespo-Leiro, María Generosa; Depasquale, Eugene D.; Deng, Mario; Goeckler, Johannes; Kim, Daniel H.; Kobashigawa, Jon; MacDonald, Peter; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas; Halloran, Philip F. (Wolters Kluwer, 2022-11)[Abstract] Background: The INTERHEART study (ClinicalTrials.gov #NCT02670408) used genome-wide microarrays to detect rejection in endomyocardial biopsies; however, many heart transplants with no rejection have late dysfunction ... -
Molecular states associated with dysfunction and graft loss in heart transplants
Halloran, Philip F.; Madill-Thomsen, Katelynn; Mackova, Martina; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martin; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Hall, Shelley A.; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas; Reeve, Jeff (Elsevier, 2023-11-30)[Abstract] Background: We explored the changes in gene expression correlating with dysfunction and graft failure in endomyocardial biopsies. Methods: Genome-wide microarrays (19,462 genes) were used to define mRNA ...