• Automatic Seizure Detection Based on Star Graph Topological Indices 

      Fernández-Blanco, Enrique; Rivero, Daniel; Rabuñal, Juan R.; Dorado, Julián; Pazos, A.; Munteanu, Cristian-Robert (Elsevier, 2012-08-15)
      [Abstract] The recognition of seizures is very important for the diagnosis of patients with epilepsy. The seizure is a process of rhythmic discharge in brain and occurs rarely and unpredictably. This behavior generates a ...
    • Random Forest Classification Based on Star Graph Topological Indices for Antioxidant Proteins 

      Fernández-Blanco, Enrique; Aguiar-Pulido, Vanessa; Munteanu, Cristian-Robert; Dorado, Julián (Elsevier, 2012-10-29)
      [Abstract] Aging and life quality is an important research topic nowadays in areas such as life sciences, chemistry, pharmacology, etc. People live longer, and, thus, they want to spend that extra time with a better quality ...
    • Biomedical data integration in computational drug design and bioinformatics 

      Seoane, José A.; Aguiar-Pulido, Vanessa; Munteanu, Cristian-Robert; Rivero, Daniel; Rabuñal, Juan R.; Dorado, Julián; Pazos, A. (Bentham Science, 2013)
      [Abstract In recent years, in the post genomic era, more and more data is being generated by biological high throughput technologies, such as proteomics and transcriptomics. This omics data can be very useful, but the real ...
    • SNP locator: a candidate SNP selection tool 

      Seoane, José A.; Aguiar-Pulido, Vanessa; Cabarcos, Alba; Quintela, Sonsoles; Rabuñal, Juan R.; Dorado, Julián (Inderscience, 2013)
      [Abstract] In this work, a data integration approach using a federated model based on a service oriented architecture (SOA) is presented. The BioMOBY middleware was used to implement each service which is part of the ...
    • Genetic programming to improvement FIB model: bond and anchorage of reinforcing steel in structural concrete 

      Pérez, Juan Luis; Vieito, Ismael; Rabuñal, Juan R.; Martínez-Abella, Fernando (Springer, 2013)
      [Abstract] Starting from the FIB database, this work is aimed to analyze the current equations which predict the main datum that can be provided by bond tests: the ultimate bar stress when the failure is reached. Furthermore, ...
    • MIANN models in medicinal, physical and organic chemistry 

      González-Díaz, Humberto; Arrasate, Sonia; Sotomayor, Nuria; Lete, Esther; Munteanu, Cristian-Robert; Pazos, A.; Besada-Porto, Lina; Ruso, Juan M. (Bentham, 2013)
      [Abstract] Reducing costs in terms of time, animal sacrifice, and material resources with computational methods has become a promising goal in Medicinal, Biological, Physical and Organic Chemistry. There are many computational ...
    • Kernel-Based Feature Selection Techniques for Transport Proteins Based on Star Graph Topological Indices 

      Fernández-Lozano, Carlos; Gestal, M.; Pedreira Souto, Nieves; Postelnicu, Lucian; Dorado, Julián; Munteanu, Cristian-Robert (Bentham, 2013)
      [Abstract] The transport of the molecules inside cells is a very important topic, especially in Drug Metabolism. The experimental testing of the new proteins for the transporter molecular function is expensive and inefficient ...
    • Feature selection and novelty in computational aesthetics 

      Correia, Joao; Machado, Penousal; Carballal, Adrián; Romero, Juan (Springer, 2013)
      [Abstract] An approach for exploring novelty in expression-based evolutionary art systems is presented. The framework is composed of a feature extractor, a classifier, an evolutionary engine and a supervisor. The evolutionary ...
    • Breast density classification to reduce false positives in CADe systems 

      Vállez, Noelia; Bueno, Gloria; Déniz, Oscar; Dorado, Julián; Seoane, José A.; Pazos, A.; Pastor, Carlos (Elsevier, 2013)
      [Abstract] This paper describes a novel weighted voting tree classification scheme for breast density classification. Breast parenchymal density is an important risk factor in breast cancer. Moreover, it is known that ...
    • Evolutionary Computation and QSAR Research 

      Aguiar-Pulido, Vanessa; Gestal, M.; Cruz-Monteagudo, Maykel; Rabuñal, Juan R.; Dorado, Julián; Munteanu, Cristian-Robert (Bentham Science, 2013)
      [Abstract] The successful high throughput screening of molecule libraries for a specific biological property is one of the main improvements in drug discovery. The virtual molecular filtering and screening relies greatly ...
    • Using Genetic Algorithms for Automatic Recurrent ANN Development: an Application to EEG Signal Classification 

      Rivero, Daniel; Aguiar-Pulido, Vanessa; Fernández-Blanco, Enrique; Gestal, M. (Inderscience, 2013)
      [Abstract] ANNs are one of the most successful learning systems. For this reason, many techniques have been published that allow the obtaining of feed-forward networks. However, fe w ...
    • S2SNet: a tool for transforming characters and numeric sequences into star network topological indices in chemoinformatics, bioinformatics, biomedical, and social-legal sciences 

      Munteanu, Cristian-Robert; Magalhaes, Alexandre L.; Duardo-Sánchez, Aliuska; Pazos, A.; González-Díaz, Humberto (Bentham, 2013)
      [Abstract] The study of complex systems such as proteins/DNA/RNA or dynamics of tax law systems can be carried out with the complex network theory. This allows the numerical quantification of the significant information ...
    • Ontologies in medicinal chemistry: current status and future challenges 

      Gómez-Pérez, Asunción; Martínez-Romero, Marcos; Rodríguez-González, Alejandro; Vázquez, Guillermo; Vázquez-Naya, José (Bentham Science, 2013)
      [Abstract] Recent years have seen a dramatic increase in the amount and availability of data in the diverse areas of medicinal chemistry, making it possible to achieve significant advances in fields such as the design, ...
    • The iOSC3 system: using ontologies and SWRL rules for intelligent supervision and care of patients with acute cardiac disorders 

      Martínez-Romero, Marcos; Vázquez-Naya, José; Pereira-Loureiro, Javier; Pereira, Miguel; Pazos, A.; Baños, Alejandro (Hindawi, 2013)
      [Abstract] Physicians in the Intensive Care Unit (ICU) are specially trained to deal constantly with very large and complex quantities of clinical data and make quick decisions as they face complications. However, the ...
    • A genetic algorithms-based approach for optimizing similarity aggregation in ontology matching 

      Martínez-Romero, Marcos; Vázquez-Naya, José; Nóvoa, Francisco; Vázquez, Guillermo; Pereira-Loureiro, Javier (Springer, 2013)
      [Abstract] Ontology matching consists of finding the semantic relations between different ontologies and is widely recognized as an essential process to achieve an adequate interoperability between people, systems or ...
    • Docencia en la nube: herramientas gratuitas 

      Groba, Betania; Nieto-Riveiro, Laura; Pousada, Thais; Pintos, Jorge (Asociación de Profesores Universitarios de Radiología y Medicina Física (APURF), 2013)
      [Resumen] La evolución del uso de Internet ha derivado hacia su utilización como un espacio común para compartir información e inclusos como sistema de almacenamiento accesible desde cualquier equipo. Esta disposición en ...
    • Exploring Patterns of Epigenetic Information With Data Mining Techniques 

      Aguiar-Pulido, Vanessa; Seoane, José A.; Gestal, M.; Dorado, Julián (Bentham, 2013-02-01)
      [Abstract] Data mining, a part of the Knowledge Discovery in Databases process (KDD), is the process of extracting patterns from large data sets by combining methods from statistics and artificial intelligence with database ...
    • The Rücker–Markov invariants of complex bio-systems: applications in parasitology and neuroinformatics 

      González-Díaz, Humberto; Riera-Fernández, Pablo; Pazos, A.; Munteanu, Cristian-Robert (Elsevier, 2013-02-23)
      [Abstract] Rücker's walk count (WC) indices are well-known topological indices (TIs) used in Chemoinformatics to quantify the molecular structure of drugs represented by a graph in Quantitative structure–activity/property ...
    • Applied Computational Techniques on Schizophrenia Using Genetic Mutations 

      Aguiar-Pulido, Vanessa; Gestal, M.; Fernández-Lozano, Carlos; Rivero, Daniel; Munteanu, Cristian-Robert (Bentham, 2013-03-01)
      [Abstract] Schizophrenia is a complex disease, with both genetic and environmental influence. Machine learning techniques can be used to associate different genetic variations at different genes with a (schizophrenic or ...
    • Classification of Signals by Means of Genetic Programming 

      Fernández-Blanco, Enrique; Rivero, Daniel; Gestal, M.; Dorado, Julián (Springer, 2013-03-30)
      [Abstract] This paper describes a new technique for signal classification by means of Genetic Programming (GP). The novelty of this technique is that no prior knowledge of the signals is needed to extract the features. ...