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Cabazitaxel for metastatic castration-resistant prostate cancer: safety data from the Spanish expanded access program
(Taylor & Francis, 2014-07-07)
[Abstract] BACKGROUND: Based on the TROPIC study results, cabazitaxel was approved for the management of metastatic castration-resistant prostate cancer (mCRPC) progressing on or after docetaxel.
METHODS: This multi-centre ...
Peritoneal water transport characteristics of diabetic patients undergoing peritoneal dialysis: a longitudinal study
(Karger, 2017-06-21)
[Abstract] Background: Volume overload is frequent in diabetics undergoing peritoneal dialysis (PD), and may play a significant role in the excess mortality observed in these patients. The characteristics of peritoneal ...
Searching for Hif1-α interacting proteins in renal cell carcinoma
(Springer para Federation of Spanish Oncology Sociesties (FESEO), 2012-08-28)
[Abstract] Introduction. Kidney tumours are frequently characterised by hypoxic conditions due to a local imbalance between oxygen (O2) supply and consumption. Hif1-α regulates angiogenesis, tumour growth, tumour progression, ...
Beneficios y riesgos de la hormona del crecimiento en adultos con déficit de la misma
(Elsevier, 2014-01-28)
[Resumen] La deficiencia de hormona del crecimiento («growth hormone», GH) en el adulto es un síndrome clínico plenamente reconocido que entraña consecuencias adversas para la salud. Muchas de ellas pueden ser mejoradas ...
Potential role of sugar transporters in cancer and their relationship with anticancer therapy
(Hindawi, 2010-06-20)
[Abstract] Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their hydrophilic nature, cells use a number of transporter proteins to introduce sugars through their plasma membrane. ...
Identification of targets for prevention of peritoneal catheter tunnel and exit-site infections in low incidence settings
(SAGE, 2016-01-01)
[Abstract] ♦ Background:
Peritoneal catheter tunnel and exit-site infection (TESI) complicates the clinical course of peritoneal dialysis (PD) patients. Adherence to recommendations for catheter insertion, exit-site care, ...
Multiple biomarker tissue arrays: a computational approach to identifying protein-protein interactions in the EGFR/ERK signalling pathway
(BioMed Central, 2012-09-01)
[Abstract]
Background. Many studies have demonstrated genetic and environmental factors that lead to renal cell carcinoma (RCC) and that occur during a protracted period of tumourigenesis. It appears suitable to identify ...
Aspectos médicos del tratamiento quirúrgico de la obesidad
(Elsevier, 2011)
Novel potential predictive markers of sunitinib outcomes in long-term responders versus primary refractory patients with metastatic clear-cell renal cell carcinoma
(Impact Journals, 2017-03-23)
[Abstract] Background: Several potential predictive markers of efficacy of targeted agents in patients with metastatic renal cell carcinoma (mRCC) have been identified. Interindividual heterogeneity warrants further ...