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Cabazitaxel for metastatic castration-resistant prostate cancer: safety data from the Spanish expanded access program
(Taylor & Francis, 2014-07-07)
[Abstract] BACKGROUND: Based on the TROPIC study results, cabazitaxel was approved for the management of metastatic castration-resistant prostate cancer (mCRPC) progressing on or after docetaxel.
METHODS: This multi-centre ...
Searching for Hif1-α interacting proteins in renal cell carcinoma
(Springer para Federation of Spanish Oncology Sociesties (FESEO), 2012-08-28)
[Abstract] Introduction. Kidney tumours are frequently characterised by hypoxic conditions due to a local imbalance between oxygen (O2) supply and consumption. Hif1-α regulates angiogenesis, tumour growth, tumour progression, ...
Potential role of sugar transporters in cancer and their relationship with anticancer therapy
(Hindawi, 2010-06-20)
[Abstract] Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their hydrophilic nature, cells use a number of transporter proteins to introduce sugars through their plasma membrane. ...
Multiple biomarker tissue arrays: a computational approach to identifying protein-protein interactions in the EGFR/ERK signalling pathway
(BioMed Central, 2012-09-01)
[Abstract]
Background. Many studies have demonstrated genetic and environmental factors that lead to renal cell carcinoma (RCC) and that occur during a protracted period of tumourigenesis. It appears suitable to identify ...
Novel potential predictive markers of sunitinib outcomes in long-term responders versus primary refractory patients with metastatic clear-cell renal cell carcinoma
(Impact Journals, 2017-03-23)
[Abstract] Background: Several potential predictive markers of efficacy of targeted agents in patients with metastatic renal cell carcinoma (mRCC) have been identified. Interindividual heterogeneity warrants further ...
Clinical implications of epithelial cell plasticity in cancer progression
(Elsevier, 2015)
[Abstract] In the last few years, the role of epithelial cell plasticity in cancer biology research has gained increasing attention. This concept refers to the ability of the epithelial cells to dynamically switch between ...
Peritoneal protein transport during the baseline peritoneal equilibration test is an accurate predictor of the outcome of peritoneal dialysis patients
(Karger, 2010)
[Abstract] Background: Peritoneal protein excretion (PPE) is a potential marker of the outcome in peritoneal dialysis (PD) patients. Method: Observational study of a cohort of 269 patients starting PD in a single unit. ...
Respuesta secretora de PYY1-36 y PYY3-36 en sujetos normales tras la ingesta de una comida mixta
(Elsevier para Sociedad Española de Endocrinología y Nutrición, 2008-12-25)
[Resumen] Introducción. El péptido YY (PYY) tiene 36 aminoácidos y lo sintetizan fundamentalmente las células L del intestino. El PYY aumenta tras las comidas y alcanza su nadir tras el ayuno. Tras la ingestión se liberan ...
Alteración de la expresión génica de Sor1 y RB1 en distintos modelos de estrés metabólico
(Sociedad Española para el Estudio de la Obesidad (SEEDO), 2018)