Mostrando ítems 46-50 de 147

    • NF-κB/IKK Activation by Small Extracellular Vesicles Within the SASP 

      Fafián Labora, Juan Antonio; O'Loghlen, Ana (Wiley, 2021-06-29)
      [Abstract] Cellular senescence plays an important role in different biological and pathological conditions. Senescent cells communicate with their microenvironment through a plethora of soluble factors, metalloproteases ...
    • High-Throughput Screen Detects Calcium Signaling Dysfunction in Hutchinson-Gilford Progeria Syndrome 

      Fafián Labora, Juan Antonio; Morente López, Miriam; De-Toro, Javier; Arufe, M.C. (MDPI, 2021-07-07)
      [Abstract] Hutchinson–Gilford progeria syndrome (HGPS) is a deadly childhood disorder, which is considered a very rare disease. It is caused by an autosomal dominant mutation on the LMNA gene, and it is characterized by ...
    • An artificial-vision- and statistical-learning-based method for studying the biodegradation of type I collagen scaffolds in bone regeneration systems 

      Robles-Bykbaev, Yaroslava; Naya, Salvador; Díaz-Prado, Silvia; Calle-López, D.; Robles-Bykbaev, Vladimir; Garzón, Luis; Sanjurjo-Rodríguez, Clara; Tarrío-Saavedra, Javier (PeerJ, 2019-07-05)
      [Abstract] This work proposes a method based on image analysis and machine and statistical learning to model and estimate osteocyte growth (in type I collagen scaffolds for bone regeneration systems) and the collagen ...
    • Cell and Tissue Transplant Strategies for Joint Lesions 

      Fuentes Boquete, Isaac Manuel; Arufe, M.C.; Díaz-Prado, Silvia; Hermida Gómez, Tamara; De-Toro, Javier; Blanco García, Francisco J (Bentham Open, 2008-07-11)
      [Abstract] Articular cartilage lesions that do not disrupt the integrity of subchondral bone are not capable of spontaneous repair. The asymptomatic nature of these lesions leads to articular cartilage degeneration and ...
    • Current Development of Alternative Treatments for Endothelial Decompensation: Cell-Based Therapy 

      Rodríguez-Fernández, Silvia; Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Álvarez Portela, Marcelino; Fuentes Boquete, Isaac Manuel; Rendal Vázquez, María Esther; Díaz-Prado, Silvia (Elsevier, 2021-04-01)
      [Abstract] Current treatment for corneal endothelial dysfunction consists in the replacement of corneal endothelium by keratoplasty. Owing to the scarcity of donor corneas and the increasing number of transplants, alternative ...