• An Efficient Ant Colony Optimization Framework for HPC Environments 

      González, Patricia; Osorio, Roberto; Pardo, Xoán C.; Banga, Julio R.; Doallo, Ramón (Elsevier, 2022)
      [Abstract] Combinatorial optimization problems arise in many disciplines, both in the basic sciences and in applied fields such as engineering and economics. One of the most popular combinatorial optimization methods is ...
    • Implementing Parallel Differential Evolution on Spark 

      Teijeiro, Diego; Pardo, Xoán C.; González, Patricia; Banga, Julio R.; Doallo, Ramón (Springer, 2016-04-02)
      [Abstract] Metaheuristics are gaining increased attention as an efficient way of solving hard global optimization problems. Differential Evolution (DE) is one of the most popular algorithms in that class. However, its ...
    • Parallel ant colony optimization for the training of cell signaling networks 

      González, Patricia; Prado-Rodriguez, Roberto; Gábor, Attila; Saez-Rodriguez, Julio; Banga, Julio R.; Doallo, Ramón (Elsevier, 2022)
      [Abstract]: Acquiring a functional comprehension of the deregulation of cell signaling networks in disease allows progress in the development of new therapies and drugs. Computational models are becoming increasingly popular ...
    • Parameter estimation in large-scale systems biology models: a parallel and self-adaptive cooperative strategy 

      Penas, David R.; González, Patricia; Egea, Jose A.; Doallo, Ramón; Banga, Julio R. (BioMed Central Ltd., 2017)
      [Abstract] Background The development of large-scale kinetic models is one of the current key issues in computational systems biology and bioinformatics. Here we consider the problem of parameter estimation in nonlinear ...
    • Spark Implementation of the Enhanced Scatter Search Metaheuristic: Methodology and Assessment 

      Pardo, Xoán C.; Argüeso-Alejandro, Pablo; González, Patricia; Banga, Julio R.; Doallo, Ramón (Elsevier BV, 2020-12)
      [Abstract] Optimization problems arise nowadays in all disciplines, not only in the scientific area but also in the field of engineering or economics, and in many others. Currently, challenging optimization problems require ...
    • Towards cloud-based parallel metaheuristics: A case study in computational biology with Differential Evolution and Spark 

      Teijeiro, Diego; Pardo, Xoán C.; González, Patricia; Banga, Julio R.; Doallo, Ramón (Sage Publications Ltd., 2016-11-28)
      [Abstract] Many key problems in science and engineering can be formulated and solved using global optimization techniques. In the particular case of computational biology, the development of dynamic (kinetic) models is ...