Listar Química molecular e de materiais (QUIMOLMAT) por autor "García, Marcos D."
Mostrando ítems 1-11 de 11
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Amino Acid–Viologen Hybrids: Synthesis, Cucurbituril Host–Guest Chemistry, and Implementation on the Production of Peptides
Barravecchia Prado, Liliana Inés; Neira, Iago; Pazos, Elena; Peinador, Carlos; García, Marcos D. (American Chemical Society, 2021-12-10)[Abstract] We present herein the development of a series of viologen–amino acid hybrids, obtained in good yields either by successive alkylations of 4,4′-bipyridine, or by Zincke reactions followed by a second alkylation ... -
CB[7]- and CB[8]-Based [2]-(Pseudo)rotaxanes with Triphenylphosphonium-Capped Threads: Serendipitous Discovery of a New High-Affinity Binding Motif
Neira, Iago; Peinador, Carlos; García, Marcos D. (American Chemical Society, 2022-05-06)[Abstract] The synthesis of new triphenylphosphonium-capped cucurbit[7]uril (CB[7])- and cucurbit[8]uril (CB[8])-based [2]rotaxanes was achieved by a simultaneous threading-capping strategy. While the use of CB[7] produced ... -
Controlled Binding of Organic Guests by Stimuli-Responsive Macrocycles
Blanco-Gómez, Arturo; Cortón, Pablo; Barravecchia Prado, Liliana Inés; Neira, Iago; Pazos, Elena; Peinador, Carlos; García, Marcos D. (Royal Society of Chemistry, 2020-05-12)[Abstract] Synthetic supramolecular chemistry pursues not only the construction of new matter, but also control over its inherently dynamic behaviour. In this context, classic host–guest chemistry, based on the development ... -
Cucurbit[8]uril (CB[8])-Based Supramolecular Switches
Pazos, Elena; Novo, Paula; Peinador, Carlos; Kaifer, Angel; García, Marcos D. (Wiley, 2018-07-06)[Abstract] The use of cucurbit[8]uril as a molecular host has emerged in the chemical literature as a reliable strategy for the creation of dynamic chemical systems, owing to its ability to form homo- and heteroternary ... -
Reversible Control of DNA Binding with Cucurbit[8]uril-Induced Supramolecular 4,4′-Bipyridinium–Peptide Dimers
Novo, Paula; García, Marcos D.; Peinador, Carlos; Pazos, Elena (American Chemical Society, 2021-03-08)[Abstract] Many cellular processes in living organisms are regulated by complex regulatory networks, built from noncovalent interactions between relatively few proteins that perform their functions by switching between ... -
Self-Assembled Peptide–Inorganic Nanoparticle Superstructures: From Component Design to Applications
Pigliacelli, Claudia; Sánchez-Fernández, Rosalía; García, Marcos D.; Peinador, Carlos; Pazos, Elena (Royal Society of Chemistry, 2020-06-04)[Abstract] Peptides have become excellent platforms for the design of peptide–nanoparticle hybrid superstructures, owing to their self-assembly and binding/recognition capabilities. Morover, peptide sequences can be encoded ... -
Subcellular duplex DNA and G‐quadruplex interaction profiling of a hexagonal PtII metallacycle
Domarco, Olaya; Kieler, Claudia; Pirker, Christine; Dinhof, Carina; Englinger, Bernhard; Reisecker, Johannes M.; Timelthaler, Gerald; García, Marcos D.; Peinador, Carlos; Keppler, Bernhard K.; Berger, Walter; Terenzi, Alessio (Wiley, 2019-04-19)[Abstract] Metal‐driven self‐assembly afforded a multitude of fascinating supramolecular coordination complexes (SCCs) with applications as catalysts, host–guest, and stimuli‐responsive systems. However, the interest in ... -
The Red Cage: Implementation of pH-Responsiveness Within a Macrobicyclic Pyridinium-Based Molecular Host
Cortón, Pablo; Wang, Hongye; Neira, Iago; Blanco-Gómez, Arturo; Pazos, Elena; Peinador, Carlos; Li, Hao; García, Marcos D. (Royal Society of Chemistry, 2021-11-09)[Abstract] We present herein the implementation of pH-responsiveness into a new polycationic macrobicyclic structure, namely what we have termed the “red cage”. The hydrolytically-stable cryptand-like compound has been ... -
Thinking Outside the Blue Box: From Molecular to Supramolecular PH-Responsiveness
Blanco-Gómez, Arturo; Neira, Iago; Barriada, José Luis; Melle-Franco, Manuel; Peinador, Carlos; García, Marcos D. (Royal Society of Chemistry, 2019-10-23)[Abstract] We present herein the development of a new polycationic cyclophane: the “red box”, second in a series of hydrazone-based analogues of the well-known organic receptor cyclobis(paraquat-p-phenylene)cyclophane ... -
Thinking Outside the Blue Box: Induced Fit within a Unique Self-Assembled Polycationic Cyclophane
Blanco-Gómez, Arturo; Fernández-Blanco, Ángel; Blanco, Víctor; Rodríguez, Jaime; Peinador, Carlos; García, Marcos D. (ACS, 2019-02-07)[Abstract] We present herein the development of a new polycationic molecular receptor, inspired by the ubiquitous cyclobis(paraquat-p-phenylene)cyclophane (“blue box”). Our analogue, the “white box”, has been easily ... -
Vermellogens and the Development of CB[8]-Based Supramolecular Switches Using pH-Responsive and Non-Toxic Viologen Analogues
Barravecchia Prado, Liliana Inés; Blanco-Gómez, Arturo; Neira, Iago; Skackauskaite, Raminta; Vila García, Alejandro; Rey-Rico, Ana; Peinador, Carlos; García, Marcos D. (ACS, 2022-10-07)[Abstract] We present herein the “vermellogens”, a new class of pH-responsive viologen analogues, which replace the direct linking between para-substituted pyridinium moieties within those by a hydrazone functional group. ...