Recent Submissions

  • In vitro and in vivo assessment of the efficacy of bromoageliferin, an alkaloid isolated from the sponge "Agelas dilatata", against "Pseudomonas aeruginosa" 

    Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Martínez-Guitián, Marta; Lasarte-Monterrubio, Cristina; Vázquez Ucha, Juan Carlos; Bou, Germán; Rodríguez, Jaime; Beceiro, Alejandro; Jiménez, Carlos (MDPI, 2020-06-23)
    [Abstract] The pyrrole-imidazoles, a group of alkaloids commonly found in marine sponges belonging to the genus Agelas, display a wide range of biological activities. Herein, we report the first chemical study of the ...
  • Marine natural products from the Yucatan peninsula 

    Pech-Puch, Dawrin; Pérez Povedano, Mar Anabel; Lenis Rojas, Oscar; Rodríguez, Jaime; Jiménez, Carlos (MDPI AG, 2020-01-16)
    [Abstract]: Mexico is one of the three areas of the world with the greatest terrestrial and cultural biological diversity. The diversity of Mexican medicinal flora has been studied for a long time and several bioactive ...
  • Thinking outside the “Blue Box”: from molecular to supramolecular pH-responsiveness 

    Blanco-Gómez, Arturo; Neira, Iago; Barriada, José Luis; Melle-Franco, Manuel; Peinador, Carlos; García, Marcos D. (Royal Society of Chemistry, 2019-10-23)
    [Abstract] We present herein the development of a new polycationic cyclophane: the “red box”, second in a series of hydrazone-based analogues of the well-known organic receptor cyclobis(paraquat-p-phenylene)cyclophane ...
  • Conjugation of different immunogenic enterococcal vaccine target antigens leads to extended strain coverage 

    Romero-Saavedra, Felipe; Laverde, Diana; Kalfopoulou, Ermioni; Martini, Cecilia; Torelli, Riccardo; Martínez Matamoros, Diana; Sanguinetti, Maurizio; Huebner, Johannes (Oxford University Press, 2019-07-09)
    [Abstract] Enterococci have emerged as important nosocomial pathogens due to their resistance to the most commonly used antibiotics. Alternative treatments or prevention options are aimed at polysaccharides and surface-related ...
  • Subcellular duplex DNA and G‐quadruplex interaction profiling of a hexagonal PtII metallacycle 

    Domarco, Olaya; Kieler, Claudia; Pirker, Christine; Dinhof, Carina; Englinger, Bernhard; Reisecker, Johannes M.; Timelthaler, Gerald; García, Marcos D.; Peinador, Carlos; Keppler, Bernhard K.; Berger, Walter; Terenzi, Alessio (Wiley, 2019-04-19)
    [Abstract] Metal‐driven self‐assembly afforded a multitude of fascinating supramolecular coordination complexes (SCCs) with applications as catalysts, host–guest, and stimuli‐responsive systems. However, the interest in ...

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