Now showing items 1-11 of 11

    • Developing the family of picolinate ligands for Mn2+ complexation 

      Forgács, Attila; Pujales-Paradela, Rosa; Regueiro-Figueroa, Martín; Valencia, Laura; Esteban-Gómez, David; Botta, Mauro; Platas-Iglesias, Carlos (Royal Society of Chemistry, 2016-12-22)
      [Abstract] We have reported here a series of ligands containing pentadentate 6,6′-(azanediylbis(methylene))dipicolinic acid units that differ in the substituent present at the amine nitrogen atom (acetate: H3DPAAA; phenyl: ...
    • Exceptionally inert lanthanide(III) PARACEST MRI contrast agents based on an 18-membered macrocyclic platform 

      Castro, Goretti; Regueiro-Figueroa, Martín; Esteban-Gómez, David; Bastida, Rufina; Macías, Alejandro; Pérez-Lourido, Paulo; Platas-Iglesias, Carlos; Valencia, Laura (Wiley, 2015-12-14)
      [Abstract] We report a macrocyclic ligand based on a 3,6,10,13-tetraaza-1,8(2,6)-dipyridinacyclotetradecaphane platform containing four hydroxyethyl pendant arms (L1) that forms extraordinary inert complexes with Ln3+ ions. ...
    • Inert macrocyclic Eu3+ complex with affirmative paraCEST features 

      Gambino, Tanja; Valencia, Laura; Pérez-Lourido, Paulo; Esteban-Gómez, David; Zaiss, Moritz; Platas-Iglesias, Carlos; Angelovski, Goran (Royal Society of Chemistry, 2020-06-21)
      [Abstract]: We report on a macrocyclic platform based on an 18-membered macrocycle that forms kinetically highly inert paramagnetic complexes and possesses an excellent outlook for the development of bioresponsive paraCEST ...
    • Magnetic anisotropies in rhombic lanthanide(III) complexes do not conform to Bleaney’s theory 

      Castro, Goretti; Regueiro-Figueroa, Martín; Esteban-Gómez, David; Pérez-Lourido, Paulo; Platas-Iglesias, Carlos; Valencia, Laura (American Chemical Society, 2016-04-04)
      [Abstract] We report a complete set of magnetic susceptibilities of lanthanide complexes with a macrocyclic ligand based on a 3,6,10,13-tetraaza-1,8(2,6)-dipyridinacyclotetradecaphane platform containing four hydroxyethyl ...
    • On the Dissociation Pathways of Copper Complexes Relevant as Pet Imaging Agents 

      Uzal-Varela, Rocío; Patinec, Véronique; Tripier, Raphaël; Valencia, Laura; Maneiro, Marcelino; Canle, Moisés; Platas-Iglesias, Carlos; Esteban-Gómez, David; Iglesias, Emilia (Elsevier, 2022)
      [Abstract] Several bifunctional chelators have been synthesized in the last years for the development of new 64Cu-based PET agents for in vivo imaging. When designing a metal-based PET probe, it is important to achieve ...
    • Synthesis and Structural Analysis of Push-Pull Imidazole-Triazole Based Fluorescent Bifunctional Chemosensor for CU2+ and FE2+ Detection 

      Da Lama Vázquez, Ana; Pérez Sestelo, José; Valencia, Laura; Esteban-Gómez, David; Sarandeses, Luis A.; Martínez, Montserrat (Elsevier, 2022-07)
      [Abstract] Fluorescent imidazole-triazole based ligands L1 and L2 have been designed as chemical push-pull chemosensors for divalent metal ions and synthesized through palladium-catalyzed cross-coupling reactions using ...
    • The relationship between NMR chemical shifts of thermally polarized and hyperpolarized 89Y complexes and their solution structures 

      Xing, Yixun; Jindal, Ashish K.; Regueiro-Figueroa, Martín; Le Fur, Mariane; Kervarec, Nelly; Zhao, Piyu; Kovacs, Zoltan; Valencia, Laura; Pérez-Lourido, Paulo; Tripier, Raphaël; Esteban-Gómez, David; Platas-Iglesias, Carlos; Sherry, A. Dean (Wiley, 2016-11-07)
      [Abstract] Recently developed dynamic nuclear polarization (DNP) technology offers the potential of increasing the NMR sensitivity of even rare nuclei for biological imaging applications. Hyperpolarized 89Y is an ideal ...
    • The role of ligand to metal charge-transfer states on the luminescence of Europium complexes with 18-membered macrocyclic ligands 

      Nonat, Aline; Esteban-Gómez, David; Valencia, Laura; Pérez-Lourido, Paulo; Barriada, José Luis; Charbonnière, Loïc J.; Platas-Iglesias, Carlos (Royal Society of Chemistry, 2019-02-27)
      [Abstract] We report a detailed study of the photophysical properties of EuIII and TbIII complexes with two ligands based on a 3,6,10,13-tetraaza-1,8(2,6)-dipyridinacyclotetradecaphane platform containing either four ...
    • Thermodynamic Stability of Mn(II) Complexes with Aminocarboxylate Ligands Analyzed Using Structural Descriptors 

      Uzal-Varela, Rocío; Pérez-Fernández, Francisco; Valencia, Laura; Rodríguez-Rodríguez, Aurora; Platas-Iglesias, Carlos; Caravan, Peter; Esteban-Gómez, David (ACS, 2022-08-22)
      [Abstract] We present a quantitative analysis of the thermodynamic stabilities of Mn(II) complexes, defined by the equilibrium constants (log KMnL values) and the values of pMn obtained as −log[Mn]free for total metal and ...
    • Understanding the Effect of the Electron Spin Relaxation on the Relaxivities of Mn(II) Complexes with Triazacyclononane Derivatives 

      Uzal-Varela, Rocío; Valencia, Laura; Lalli, Daniela; Maneiro, Marcelino; Esteban-Gómez, David; Platas-Iglesias, Carlos; Botta, Mauro; Rodríguez-Rodríguez, Aurora (American Chemical Society, 2021-10-07)
      [Abstract] Investigating the relaxation of water ¹H nuclei induced by paramagnetic Mn(II) complexes is important to understand the mechanisms that control the efficiency of contrast agents used in diagnostic magnetic ...
    • Versatile Macrocyclic Platform for the Complexation of [ⁿᵃᵗY/⁹⁰Y]Yttrium and Lanthanide Ions 

      Harriswangler, Charlene; Caneda-Martínez, Laura; Rousseaux, Olivier; Esteban-Gómez, David; Fougère, Olivier; Pujales-Paradela, Rosa; Valencia, Laura; Fernández-Pérez, María-Isabel; Lepareur, Nicolas; Platas-Iglesias, Carlos (American Chemical Society, 2022-04-14)
      [Abstract] We report a macrocyclic ligand (H3L6) based on a 3,6,10,13-tetraaza-1,8(2,6)-dipyridinacyclotetradecaphane platform containing three acetate pendant arms and a benzyl group attached to the fourth nitrogen atom ...