Listar por autor "Poza, Margarita"

Mostrando ítems 1-16 de 16

    • A New and Efficient Enrichment Method for Metagenomic Sequencing of Monkeypox Virus 

      Aja-Macaya, Pablo; Rumbo-Feal, Soraya; Poza, Margarita; Cañizares Castellanos, Angelina; Vallejo, J.A.; Bou, Germán (Springer, 2022-01-17)
      [Abstract] Background The methodology described in previous literature for Monkeypox virus (MPXV) sequencing shows low efficiency when using metagenomic approaches. The aim of the present study was to evaluate a new ...

    • Automation Proposal for the Intermediate Steps in the 16S FFPE Samples Analysis Pipeline 

      Martín de Arribas, Elsa; Conde-Pérez, Kelly; Aja-Macaya, Pablo; Vallejo, J.A.; Poza, Margarita; Ladra, Susana (Universidade da Coruña, Servizo de Publicacións, 2023)
      [Abstract] In the day-to-day work of bioinformatics, the use of integrated software packages, which encompass a wide range of tools, enables the development of pipelines for omics data analysis. Within the various existing ...

    • Building-Scale Wastewater-Based Epidemiology for SARS-CoV-2 Surveillance at Nursing Homes in A Coruña, Spain 

      Trigo-Tasende, Noelia; Vallejo, J.A.; Rumbo-Feal, Soraya; Conde-Pérez, Kelly; Nasser-Ali, Mohammed; Tarrío-Saavedra, Javier; Barbeito, Inés; Cao, Ricardo; Ladra, Susana; Bou, Germán; Poza, Margarita (MDPI, 2023-11)
      [Abstract] Wastewater-based epidemiology (WBE) has become an effective tool in the surveillance of infectious diseases such as COVID-19. In this work, we performed a brief study of monitoring the SARS-CoV-2 viral load ...

    • Draft Genome Sequences of Two Epidemic OXA-48-Producing Klebsiella pneumoniae Clinical Strains Isolated during a Large Outbreak in Spain 

      Poza, Margarita; Gato, Eva; Álvarez-Fraga, Laura; Vallejo, J.A.; Rumbo-Feal, Soraya; Martínez-Guitián, Marta; Beceiro, Alejandro; Bou, Germán; Pérez Gómez, Astrid (American Society for Microbiology, 2018)
      [Abstract] We report here the draft genome sequences of Klebsiella pneumoniae strains Kp1803 and Kp3380 isolated during a large outbreak at A Coruña Hospital in Spain. The final genome assemblies for Kp1803 and Kp3380 ...

    • In-Depth Analysis of the Role of the Acinetobactin Cluster in the Virulence of Acinetobacter baumannii 

      Conde-Pérez, Kelly; Vázquez-Ucha, Juan Carlos; Álvarez-Fraga, Laura; Ageitos, Lucía; Rumbo-Feal, Soraya; Martínez-Guitián, Marta; Trigo Tasende, Noelia; Rodríguez, Jaime; Bou, Germán; Jiménez, Carlos; Beceiro, Alejandro; Poza, Margarita (Frontiers, 2021-10-05)
      [Abstract] Acinetobacter baumannii is a multidrug-resistant pathogen that represents a serious threat to global health. A. baumannii possesses a wide range of virulence factors that contribute to the bacterial pathogenicity. ...

    • Involvement of HisF in the persistence of Acinetobacter baumannii during a pneumonia infection 

      Martínez-Guitián, Marta; Vázquez-Ucha, Juan Carlos; Álvarez-Fraga, Laura; Conde-Pérez, Kelly; Lasarte-Monterrubio, Cristina; Vallejo, J.A.; Bou, Germán; Poza, Margarita; Beceiro, Alejandro (Frontiers, 2019)
      [Abstract] Acinetobacter baumannii is currently considered one of themost problematic nosocomial microorganisms. In the present work the hisF gene from the ATCC 17978 strain and the AbH12O-A2 clinical isolate of A. baumannii ...

    • Kpi, a Chaperone-Usher Pili System Associated with the Worldwide-Disseminated High-Risk Clone Klebsiella Pneumoniae ST-15 

      Gato, Eva; Vázquez-Ucha, Juan Carlos; Rumbo-Feal, Soraya; Álvarez-Fraga, Laura; Vallejo, J.A.; Martínez-Guitián, Marta; Beceiro, Alejandro; Ramos Vivas, Jose; Sola-Campoy, Pedro Juan; Pérez-Vázquez, María; Oteo, Jesús; Rodiño-Janeiro, Bruno Kotska; Romero, Antonio; Poza, Margarita; Bou, Germán; Pérez, Astrid (National Academy of Sciences, 2020-07-08)
      [Abstract] Control of infections caused by carbapenem-resistant Klebsiella pneumoniae continues to be challenging. The success of this pathogen is favored by its ability to acquire antimicrobial resistance and to spread ...

    • Microbiome in Immune-Mediated Uveitis 

      Poza, Margarita; Rodríguez-Fernández, Carmen Antía; Busto Iglesias, Manuel; Domingo, Begoña de; Conde-Pérez, Kelly; Vallejo, J.A.; Rodríguez Martínez, Lorena; González Barcia, Miguel; Llorenç, Victor; Mondelo-García, Cristina; Fernández Ferreiro, Anxo (MDPI, 2022)
      [Abstract] In the last decades, personalized medicine has been increasing its presence in different fields of medicine, including ophthalmology. A new factor that can help us direct medicine towards the challenge of ...

    • Modeling the Number of People Infected With SARS-COV-2 From Wastewater Viral Load in Northwest Spain 

      Vallejo, J.A.; Trigo Tasende, Noelia; Rumbo-Feal, Soraya; Conde-Pérez, Kelly; López-Oriona, Ángel; Barbeito, Inés; Vaamonde, Manuel; Tarrío-Saavedra, Javier; Reif López, Rubén; Ladra, Susana; Rodiño-Janeiro, Bruno Kotska; Nasser-Ali, Mohammed; Cid, Ángeles; Veiga, María Carmen; Acevedo, Antón; Lamora, Carlos; Bou, Germán; Cao, Ricardo; Poza, Margarita (Elsevier, 2022)
      [Abstract] The quantification of the SARS-CoV-2 RNA load in wastewater has emerged as a useful tool to monitor COVID–19 outbreaks in the community. This approach was implemented in the metropolitan area of A Coruña (NW ...

    • Parvimonas micra can translocate from the subgingival sulcus of the human oral cavity to colorectal adenocarcinoma 

      Ladra, Susana; Poza, Margarita; Conde-Pérez, Kelly; Buetas, Elena; Aja-Macaya, Pablo; Martin-De Arribas, E.; Iglesias Corrás, Iago; Trigo-Tasende, Noelia; Nasser-Ali, Mohammed; Estévez, Lara; Rumbo-Feal, Soraya; Otero Alén, Begoña; Noguera, José Francisco; Concha, Ángel; Pardiñas López, Simón; Carda-Diéguez, Miguel; Gómez-Randulfe Rodríguez, Martín Igor; Martinez-Lago, Nieves; Aparicio, Luis A.; Bou, Germán; Mira, Alex; Vallejo, J.A. (2023)
      [Abstract] Oral and intestinal samples from a cohort of 93 colorectal cancer (CRC) patients and 30 healthy controls (non-CRC) were collected for microbiome analysis. Saliva (28 non-CRC and 94 CRC), feces (30 non-CRC and ...

    • Pneumonia infection in mice reveals the involvement of the feoA gene in the pathogenesis of Acinetobacter baumannii 

      Poza, Margarita; Álvarez-Fraga, Laura; Vázquez-Ucha, Juan Carlos; Martínez-Guitián, Marta; Vallejo, J.A.; Bou, Germán; Beceiro, Alejandro (Taylor and Francis, 2018)
      [Abstract] Acinetobacter baumannii has emerged in the last decade as an important nosocomial pathogen. To identify genes involved in the course of a pneumonia infection, gene expression profiles were obtained from A. ...

    • Proyecto COVIDBENS. Seguimiento de la pandemia de COVID-19 en aguas residuales del área metropolitana de A Coruña 

      Trigo-Tasende, Noelia; Vaamonde, Manuel; Paramá, José R.; Tarrío-Saavedra, Javier; López-de-Ulibarri, Ignacio; Vallejo, J.A.; Ladra, Susana; Cao, Ricardo; Poza, Margarita (Sociedad Española de Sanidad Ambiental, 2022-05-18)
      [Resumen]: El virus SARS-CoV-2 está compuesto por una nucleocápside que engloba su material genético y la proteína N, rodeada por una membrana bilipídica, que contiene las proteínas M y E, y una corona de espinas, que ...

    • Quorum Sensing as a Target for Controlling Surface Associated Motility and Biofilm Formation in Acinetobacter Baumannii ATCC® 17978TM 

      Mayer, Celia; Muras, Andrea; Parga, Ana; Romero, Manuel; Rumbo-Feal, Soraya; Poza, Margarita; Ramos Vivas, Jose; Otero, Ana (Frontiers, 2020-09-30)
      [Abstract] The important nosocomial pathogen Acinetobacter baumannii presents a quorum sensing (QS) system (abaI/abaR) mediated by acyl-homoserine-lactones (AHLs) and several quorum quenching (QQ) enzymes. However, the ...

    • Syzygium aromaticum (clove) and Thymus zygis (thyme) essential oils increase susceptibility to colistin in the nosocomial pathogens Acinetobacter baumannii and Klebsiella pneumoniae 

      Poza, Margarita; Vázquez-Ucha, Juan Carlos; Martínez-Guitián, Marta; Lasarte-Monterrubio, Cristina; Conde-Pérez, Kelly; Arca-Suárez, Jorge; Álvarez-Fraga, Laura; Pérez Gómez, Astrid; Crecente-Campo, José; Alonso, María J.; Bou, Germán; Beceiro, Alejandro (Elsevier, 2020)
      [Abstract] The discovery of new antibiotics that are effective against Acinetobacter baumannii and Enterobacteralesis a research priority. Several essential oils (EOs) have displayed some antimicrobial activity and could ...

    • The multispecies microbial cluster of Fusobacterium, Parvimonas, Bacteroides and Faecalibacterium as a precision biomarker for colorectal cancer diagnosis 

      Ladra, Susana; Poza, Margarita; Conde-Pérez, Kelly; Aja-Macaya, Pablo; Buetas, Elena; Trigo-Tasende, Noelia; Nasser-Ali, Mohammed; Rumbo-Feal, Soraya; Nión Cabeza, Paula; Martin-De Arribas, E.; Estévez, Lara; Otero Alén, Begoña; Noguera, José Francisco; Concha, Ángel; Pardiñas López, Simón; Carda-Diéguez, Miguel; Gómez-Randulfe Rodríguez, Martín Igor; Martinez-Lago, Nieves; Aparicio, Luis A.; Bou, Germán; Mira, Alex; Vallejo, J.A. (Wiley, 2024)
      [Abstract] The incidence of colorectal cancer (CRC) has increased worldwide, and early diagnosis is crucial to reduce mortality rates. Therefore, new noninvasive biomarkers for CRC are required. Recent studies have revealed ...

    • Wastewater early warning system for SARS-CoV-2 outbreaks and variants in a Coruña, Spain 

      Trigo-Tasende, Noelia; Vallejo, Juan Andrés; Rumbo-Feal, Soraya; Conde-Pérez, Kelly; Vaamonde, Manuel; López-Oriona, Ángel; Barbeito, Inés; Nasser-Ali, Mohammed; Reif López, Rubén; Rodiño-Janeiro, Bruno Kotska; Fernández-Álvarez, Elisa; Iglesias Corrás, Iago; Tarrío-Saavedra, Javier; Tomás, Laura; Gallego-García, Pilar; Posada, David; Bou, Germán; López-de-Ullibarri, Ignacio; Cao, Ricardo; Susana, Ladra; Poza, Margarita (Springer, 2023-07)
      [Abstract]: Wastewater-based epidemiology has been widely used as a cost-effective method for tracking the COVID-19 pandemic at the community level. Here we describe COVIDBENS, a wastewater surveillance program running ...