• A New and Efficient Enrichment Method for Metagenomic Sequencing of Monkeypox Virus 

      Aja-Macaya, Pablo; Rumbo-Feal, Soraya; Poza, Margarita; Cañizares Castellanos, Angelina; Vallejo, J. A.; Bou, Germán (Springer, 2022-01-17)
      [Abstract] Background The methodology described in previous literature for Monkeypox virus (MPXV) sequencing shows low efficiency when using metagenomic approaches. The aim of the present study was to evaluate a new ...
    • Automation Proposal for the Intermediate Steps in the 16S FFPE Samples Analysis Pipeline 

      Martín de Arribas, Elsa; Conde-Pérez, Kelly; Aja-Macaya, Pablo; Vallejo, J. A.; Poza, Margarita; Ladra, Susana (Universidade da Coruña, Servizo de Publicacións, 2023)
      [Abstract] In the day-to-day work of bioinformatics, the use of integrated software packages, which encompass a wide range of tools, enables the development of pipelines for omics data analysis. Within the various existing ...
    • Building-Scale Wastewater-Based Epidemiology for SARS-CoV-2 Surveillance at Nursing Homes in A Coruña, Spain 

      Trigo-Tasende, Noelia; Vallejo, J.A.; Rumbo-Feal, Soraya; Conde-Pérez, Kelly; Nasser-Ali, Mohammed; Tarrío-Saavedra, Javier; Barbeito, Inés; Cao, Ricardo; Ladra, Susana; Bou, Germán; Poza, Margarita (MDPI, 2023-11)
      [Abstract] Wastewater-based epidemiology (WBE) has become an effective tool in the surveillance of infectious diseases such as COVID-19. In this work, we performed a brief study of monitoring the SARS-CoV-2 viral load ...
    • In-Depth Analysis of the Role of the Acinetobactin Cluster in the Virulence of Acinetobacter baumannii 

      Conde-Pérez, Kelly; Vázquez-Ucha, Juan Carlos; Álvarez-Fraga, Laura; Ageitos, Lucía; Rumbo-Feal, Soraya; Martínez-Guitián, Marta; Trigo Tasende, Noelia; Rodríguez, Jaime; Bou, Germán; Jiménez, Carlos; Beceiro, Alejandro; Poza, Margarita (Frontiers, 2021-10-05)
      [Abstract] Acinetobacter baumannii is a multidrug-resistant pathogen that represents a serious threat to global health. A. baumannii possesses a wide range of virulence factors that contribute to the bacterial pathogenicity. ...
    • Involvement of HisF in the persistence of Acinetobacter baumannii during a pneumonia infection 

      Martínez-Guitián, Marta; Vázquez-Ucha, Juan Carlos; Álvarez-Fraga, Laura; Conde-Pérez, Kelly; Lasarte-Monterrubio, Cristina; Vallejo, J. A.; Bou, Germán; Poza, Margarita; Beceiro, Alejandro (Frontiers, 2019)
      [Abstract] Acinetobacter baumannii is currently considered one of themost problematic nosocomial microorganisms. In the present work the hisF gene from the ATCC 17978 strain and the AbH12O-A2 clinical isolate of A. baumannii ...
    • Kpi, a Chaperone-Usher Pili System Associated with the Worldwide-Disseminated High-Risk Clone Klebsiella Pneumoniae ST-15 

      Gato, Eva; Vázquez-Ucha, Juan Carlos; Rumbo-Feal, Soraya; Álvarez-Fraga, Laura; Vallejo, J. A.; Martínez-Guitián, Marta; Beceiro, Alejandro; Ramos Vivas, Jose; Sola-Campoy, Pedro Juan; Pérez-Vázquez, María; Oteo, Jesús; Rodiño-Janeiro, Bruno Kotska; Romero, Antonio; Poza, Margarita; Bou, Germán; Pérez, Astrid (National Academy of Sciences, 2020-07-08)
      [Abstract] Control of infections caused by carbapenem-resistant Klebsiella pneumoniae continues to be challenging. The success of this pathogen is favored by its ability to acquire antimicrobial resistance and to spread ...
    • Modeling the Number of People Infected With SARS-COV-2 From Wastewater Viral Load in Northwest Spain 

      Vallejo, J. A.; Trigo Tasende, Noelia; Rumbo-Feal, Soraya; Conde-Pérez, Kelly; López-Oriona, Ángel; Barbeito, Inés; Vaamonde, Manuel; Tarrío-Saavedra, Javier; Reif López, Rubén; Ladra, Susana; Rodiño-Janeiro, Bruno Kotska; Nasser-Ali, Mohammed; Cid, Ángeles; Veiga, María Carmen; Acevedo, Antón; Lamora, Carlos; Bou, Germán; Cao, Ricardo; Poza, Margarita (Elsevier, 2022)
      [Abstract] The quantification of the SARS-CoV-2 RNA load in wastewater has emerged as a useful tool to monitor COVID–19 outbreaks in the community. This approach was implemented in the metropolitan area of A Coruña (NW ...
    • Proyecto COVIDBENS. Seguimiento de la pandemia de COVID-19 en aguas residuales del área metropolitana de A Coruña 

      Trigo-Tasende, Noelia; Vaamonde, Manuel; Paramá, José R.; Tarrío-Saavedra, Javier; López-de-Ulibarri, Ignacio; Vallejo, J.A.; Ladra, Susana; Cao, Ricardo; Poza, Margarita (Sociedad Española de Sanidad Ambiental, 2022-05-18)
      [Resumen]: El virus SARS-CoV-2 está compuesto por una nucleocápside que engloba su material genético y la proteína N, rodeada por una membrana bilipídica, que contiene las proteínas M y E, y una corona de espinas, que ...
    • Quorum Sensing as a Target for Controlling Surface Associated Motility and Biofilm Formation in Acinetobacter Baumannii ATCC® 17978TM 

      Mayer, Celia; Muras, Andrea; Parga, Ana; Romero, Manuel; Rumbo-Feal, Soraya; Poza, Margarita; Ramos Vivas, Jose; Otero, Ana (Frontiers, 2020-09-30)
      [Abstract] The important nosocomial pathogen Acinetobacter baumannii presents a quorum sensing (QS) system (abaI/abaR) mediated by acyl-homoserine-lactones (AHLs) and several quorum quenching (QQ) enzymes. However, the ...
    • Wastewater early warning system for SARS-CoV-2 outbreaks and variants in a Coruña, Spain 

      Trigo-Tasende, Noelia; Vallejo, Juan Andrés; Rumbo-Feal, Soraya; Conde-Pérez, Kelly; Vaamonde, Manuel; López-Oriona, Ángel; Barbeito, Inés; Nasser-Ali, Mohammed; Reif López, Rubén; Rodiño-Janeiro, Bruno Kotska; Fernández-Álvarez, Elisa; Iglesias Corrás, Iago; Tarrío-Saavedra, Javier; Tomás, Laura; Gallego-García, Pilar; Posada, David; Bou, Germán; López-de-Ullibarri, Ignacio; Cao, Ricardo; Susana, Ladra; Poza, Margarita (Springer, 2023-07)
      [Abstract]: Wastewater-based epidemiology has been widely used as a cost-effective method for tracking the COVID-19 pandemic at the community level. Here we describe COVIDBENS, a wastewater surveillance program running ...