Listar por autor "Fuentes Boquete, Isaac Manuel"
Mostrando ítems 1-20 de 53
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3, 3′, 5-triiodo-L-thyronine increases in vitro chondrogenesis of mesenchymal stem cells from human umbilical cord stroma through SRC2
Fernández-Pernas, Pablo; Fafián Labora, Juan Antonio; Lesende-Rodríguez, Iván; Mateos, Jesús; Fuente, Alexandre de la; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Arufe, M.C. (Wiley, 2016-07-08)[Abstract] Our group focuses on the study of mesenchymal stem cells (MSCs) from human umbilical cord stroma or Warthońs jelly and their directed differentiation toward chondrocyte-like cells capable of regenerating damaged ... -
A dinamización lingüística no ámbito da sanidade
Fuentes Boquete, Isaac Manuel; Yáñez Brage, María Isabel (Universidade da Coruña, 2011) -
Alternative protocols to induce chondrogenic differentiation: transforming growth factor-β superfamily
Cicione, Claudia; Muiños Gómez, Emma; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia; Blanco García, Francisco J (Springer, 2014-09-10)[Abstract] Mesenchymal stem cells (MSCs) are an accepted candidate for cell-based therapy of multiple diseases. The interest in MSCs and their possible application in cell therapy have resulted in a better understanding ... -
Analysis of Cryopreservation Protocols and Their Harmful Effects on the Endothelial Integrity of Human Corneas
Rodríguez-Fernández, Silvia; Álvarez-Portela, Marcelino; Rendal Vázquez, María Esther; Piñeiro-Ramil, María; Sanjurjo-Rodríguez, Clara; Castro Viñuelas, Rocío; Sánchez-Ibáñez, Jacinto; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia (MDPI, 2021-11-22)[Abstract] Corneal cryopreservation can partially solve the worldwide concern regarding donor cornea shortage for keratoplasties. In this study, human corneas were cryopreserved using two standard cryopreservation protocols ... -
Analysis of the chondrogenic potential and secretome of mesenchymal stem cells derived from human umbilical cord stroma
Arufe, M.C.; Fuente, Alexandre de la; Mateos, Jesús; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J (Mary Ann Liebert, 2011-06-28)[Abstract] Mesenchymal stem cells (MSCs) from umbilical cord stroma were isolated by plastic adherence and characterized by flow cytometry, looking for cells positive for OCT3/4 and SSEA-4 as well as the classic MSC markers ... -
Anatomía del sistema digestivo
De-Toro, Javier; Fuentes Boquete, Isaac Manuel (Universidade da Coruña, 2005) -
Biomedical Applications of the Biopolymer Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV): Drug Encapsulation and Scaffold Fabrication
Rodríguez-Cendal, Ana Isabel; Gómez-Seoane, Iván; De-Toro, Javier; Fuentes Boquete, Isaac Manuel; Señarís, José; Díaz-Prado, Silvia (MDPI, 2023-07-19)[Abstract] Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV) is a biodegradable and biocompatible biopolymer that has gained popularity in the field of biomedicine. This review provides an overview of recent advances and ... -
Bone marrow cells immunomagnetically selected for CD271+ antigen promote in vitro the repair of articular cartilage defects
Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Gimeno-Longas, María José; Muíños-López, Emma; Díaz-Prado, Silvia; De-Toro, Javier; Blanco García, Francisco J (Mary Ann Liebert, 2011-03-22)[Abstract] Objective: The purposes of this project were to quantify the cells expressing the mesenchymal stem cell (MSC) marker CD271 in synovial membranes from human osteoarthritic (OA) and healthy joints, and to determine ... -
Cartilage tissue engineering: adult human mesenchymal stromal cells and collagen biomaterials
Sanjurjo-Rodríguez, Clara; Martínez Sánchez, A.H.; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Buján, J.; De-Toro, Javier; Díaz-Prado, Silvia; Blanco García, Francisco J (Elsevier, 2014-03-20) -
CD105+-mesenchymal stem cells migrate into osteoarthritis joint: an animal model
Fernández-Pernas, Pablo; Rodríguez-Lesende, Iván; Fuente, Alexandre de la; Mateos, Jesús; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Arufe, M.C. (PLoS, 2017-11-30)[Abstract] Mesenchymal stem cells are being the focus of connective tissue technology and regenerative medicine, presenting a good choice cell source for improving old and well recognized techniques of cartilage defect ... -
Cell and Tissue Transplant Strategies for Joint Lesions
Fuentes Boquete, Isaac Manuel; Arufe, M.C.; Díaz-Prado, Silvia; Hermida Gómez, Tamara; De-Toro, Javier; Blanco García, Francisco J (Bentham Open, 2008-07-11)[Abstract] Articular cartilage lesions that do not disrupt the integrity of subchondral bone are not capable of spontaneous repair. The asymptomatic nature of these lesions leads to articular cartilage degeneration and ... -
Cell therapy and tissue engineering for cartilage repair
Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J; Díaz-Prado, Silvia (IntechOpen, 2018-02-14)[Abstract] The integrity of the articular cartilage is necessary for the proper functioning of the diarthrodial joint. The self-repair capacity of this tissue is very limited and, currently, there is no effective treatment ... -
Cell viability assay in corneal endothelium
Rodríguez-Fernández, Silvia; Álvarez Portela, Marcelino; Rendal Vázquez, María Esther; Montero Salinas, Alejandro; Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Rojas, María Victoria de; Sánchez Ibáñez, Jacinto; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia (2018)[Abstract] Introduction: Endothelium is the inner layer of the cornea, which must be viable for transplanting. The limited availability of corneas makes necessary the developing of preservation ... -
Chondrogenic Potential of Subpopulations of Cells Expressing Mesenchymal Stem Cell Markers Derived from Human Synovial Membranes
Arufe, M.C.; Fuente, Alexandre de la; Fuentes Boquete, Isaac Manuel; De-Toro, Javier; Blanco García, Francisco J (Wiley, 2010-07-21)[Abstract] In this study we analyzed the chondrogenic potential of subpopulations of mesenchymal stem cells (MSCs) derived from human synovial membranes enriched for CD73, CD106, and CD271 markers. Subpopulations of human ... -
Corneal cryopreservation: and endothelial cell viability and histomorphological study of cornea
Rodríguez-Fernández, Silvia; Álvarez Portela, Marcelino; Rendal Vázquez, María Esther; Montero Salinas, Alejandro; Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Rojas, María Victoria de; Sánchez Ibáñez, Jacinto; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia (2019) -
Criopreservación de córnea: estudio de la viabilidad celular endotelial y de la histomofología de la córnea
Rodríguez-Fernández, Silvia; Álvarez Portela, Marcelino; Rendal Vázquez, María Esther; Montero Salinas, Alejandro; Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Rojas, María Victoria de; Sánchez Ibáñez, Jacinto; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia (2019) -
Cryopreservation effect on proliferative and chondrogenic potential of human chondrocytes isolated from superficial and deep cartilage
Muíños López, Emma; Rendal Vázquez, María Esther; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia; Blanco García, Francisco J (Bentham Open, 2012-04-06)[Abstract] Objectives: To compare the proliferative and chondrogenic potential of fresh and frozen chondrocytes isolated from superficial and deep articular cartilage biopsies. Materials and Methodology: The study ... -
Current Development of Alternative Treatments for Endothelial Decompensation: Cell-Based Therapy
Rodríguez-Fernández, Silvia; Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Sanjurjo-Rodríguez, Clara; Álvarez Portela, Marcelino; Fuentes Boquete, Isaac Manuel; Rendal Vázquez, María Esther; Díaz-Prado, Silvia (Elsevier, 2021-04-01)[Abstract] Current treatment for corneal endothelial dysfunction consists in the replacement of corneal endothelium by keratoplasty. Owing to the scarcity of donor corneas and the increasing number of transplants, alternative ... -
Detección de la viabilidad celular sobre endotelio corneal
Rodríguez-Fernández, Silvia; Álvarez Portela, Marcelino; Rendal Vázquez, María Esther; Montero Salinas, Alejandro; Piñeiro-Ramil, María; Castro Viñuelas, Rocío; Rojas, María Victoria de; Sánchez Ibáñez, Jacinto; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia (2018) -
Differentiation of human mesenchymal stromal cells cultured on collagen sponges for cartilage repair
Sanjurjo-Rodríguez, Clara; Martínez Sánchez, Adela Helvia; Hermida Gómez, Tamara; Fuentes Boquete, Isaac Manuel; Díaz-Prado, Silvia; Blanco García, Francisco J (Sociedad Española de Histología e Ingeniería Tisular, 2016)[Abstract] Aim: The aim of this study was to evaluate proliferation and chondrogenic differentiation of human bone-marrow mesenchymal stromal cells (hBMSCs) cultured on collagen biomaterials. Materials and methods: ...