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Is osteoarthritis a mitochondrial disease?: what is the evidence
(Wolters Kluwer, 2022-01)
[Abstract] Propose of review: To summarize the evidence that suggests that osteoarthritis (OA) is a mitochondrial disease.
Recent findings: Mitochondrial dysfunction together with mtDNA damage could contribute to cartilage ...
Quantitative CT of the knee in the IMI-APPROACH osteoarthritis cohort: Association of bone mineral density with radiographic disease severity, meniscal coverage and meniscal extrusion
(Elsevier, 2023-03)
[Abstract] Objective: Osteoarthritis (OA) is a highly prevalent chronic condition. The subchondral bone plays an important role in onset and progression of OA making it a potential treatment target for disease-modifying ...
Generation of human immortalized chondrocytes from osteoarthritic and healthy cartilage
(The British Editorial Society of Bone & Joint Surgery, 2023-01-17)
[Abstract] Aims. After a few passages of in vitro culture, primary human articular chondrocytes undergo senescence and loss of their phenotype. Most of the available chondrocyte cell lines have been obtained from cartilage ...