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Treatment with growth hormone for adults with growth hormone deficiency syndrome: benefits and risks
(MDPI, 2018-03-17)
[Abstract] Pharmacological treatment of growth hormone deficiency (GHD) in adults began in clinical practice more than 20 years ago. Since then, a great volume of experience has been accumulated on its effects on the ...
The decreased growth hormone response to growth hormone releasing hormone in obesity is associated to cardiometabolic risk factors
(Hindawi, 2010)
[Abstract] The aim of the present study was to evaluate the relationship between GHRH-induced GH secretion in obese premenopausal women and cardiovascular risk markers or insulin resistance. Premenopausal obese women, aged ...
Alteración de la expresión génica de Sor1 y RB1 en distintos modelos de estrés metabólico
(Sociedad Española para el Estudio de la Obesidad (SEEDO), 2018)
Altered fasting and postprandial plasma ghrelin levels in patients with liver failure are normalized after liver transplantation
(Bioscientifica para European Society for Endocrinology, 2010)
[Abstract]
Context Anorexia is a problem of paramount importance in patients with advanced liver failure. Ghrelin has important actions on feeding and weight homeostasis. Experimental data exist, which suggest that ghrelin ...
Ghrelin and lipid metabolism: key partners in energy balance
(Bioscientifica para Society for Endocrinoloogy, 2011-04-01)
[Abstract] Ghrelin, the endogenous ligand of the GH secretagogue receptor, has a pleiotropic role in the modulation of energy balance. Recent evidence has demonstrated that besides its orexigenic role, ghrelin regulates ...
Clinical manifestations and diagnosis of acromegaly
(Hindawi, 2012)
[Abstract] Acromegaly and gigantism are due to excess GH production, usually as a result of a pituitary adenoma. The incidence of acromegaly is 5 cases per million per year and the prevalence is 60 cases per million. ...
Non-functioning pituitary adenoma underwent surgery: a multicenter retrospective study over the last four decades (1977–2015)
(Elsevier, 2017-04-04)
[Abstract] Objective. To assess clinical features, diagnostic procedures, therapies and outcomes in patients with clinically non-functioning pituitary adenomas (NFPAs) surgically treated over the last four decades.
Design ...
Effect of oral glucose administration on rebound growth hormone release in normal and obese women: the role of adiposity, insulin sensitivity and ghrelin
(PLoS ONE, 2015-03-17)
[Abstract] Context. Metabolic substrates and nutritional status play a major role in growth hormone (GH) secretion. Uncovering the mechanisms involved in GH secretion following oral glucose (OG) administration in normal ...
Tissue effects of glutamine in rectal cancer patients treated with preoperative chemoradiotherapy
(SENPE (Sociedad Española de Nutrición Parentelar y Entelar), 2015)
[Abstract] Background: The aim was to evaluate the effects of glutamine on tumor regression and histological damage in patients with rectal patients following chemoradiotherapy previous to surgery.
Material and methods: ...