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Indoleamine, 2-3 dioxygenase activity could be an early marker of graft rejection in heart transplantation
(Elsevier, 2012-11-10)
[Abstract] Background. The indoleamine, 2-3 dioxygenase (IDO) is an inducible intracellular enzyme with immunosuppressive effects mainly on lymphocyte populations. It has been postulated that indirect determination of IDO ...
Preoperative toxoplasma gondii serostatus does not affect long-term survival of cardiac transplant recipients: analysis of the Spanish Heart Transplantation Registry
(Elsevier, 2017-10-07)
[Abstract] Background. It's unclear whether pre-transplant T. gondii seropositivity is associated with impaired survival in heart transplant recipients.
Objectives. To test the above-mentioned hypothesis in the Spanish ...
Mitochondrial Pyruvate Carrier Abundance Mediates Pathological Cardiac Hypertrophy
(Springer Nature, 2020-10-26)
[Abstract]
Cardiomyocytes rely on metabolic substrates, not only to fuel cardiac output, but also for growth and remodelling during stress. Here we show that mitochondrial pyruvate carrier (MPC) abundance mediates ...
Oxygen therapy and palliative care in patients with heart failure. Response
(Elsevier, 2020-05-04)
Incidence, Risk Factors and Prognostic Impact of Cytomegalovirus Infection After Heart Transplantation
(Elsevier, 2020-03-20)
[Abstract] Introduction and objectives. To assess the risk factors of CMV infection after heart transplant (HT) and its influence on long-term prognosis.
Methods. We conducted a retrospective single-centre study of ...
Atlas of the clinical genetics of human dilated cardiomyopathy
(Oxford para European Society of Cardiology, 2014-08-27)
[Abstract] Aim. Numerous genes are known to cause dilated cardiomyopathy (DCM). However, until now technological limitations have hindered elucidation of the contribution of all clinically relevant disease genes to DCM ...
Prognostic Implications of Pathogenic Truncating Variants in the TTN Gene
(Elsevier, 2020-05-01)
[Abstract]
Introduction and objectives: TTN gene truncating variants (TTNtv) are a frequent cause of dilated cardiomyopathy
(DCM). However, there are discrepant data on the associated prognosis. Our objectives were to ...
Hyperkalemia in Heart Failure Patients in Spain and Its Impact on Guidelines and Recommendations: ESC-EORP-HFA Heart Failure Long-Term Registry
(Elsevier, 2020-04)
[Abstract] Introduction and objectives: Hyperkalemia is a growing concern in the treatment of patients with heart failure and reduced ejection fraction because it limits the use of effective drugs. We report estimates of ...
In-hospital postoperative infection after heart transplantation: risk factors and development of a novel predictive score
(Wiley, 2019-05-11)
[Abstract] Introduction: Infection is one of the most significant complications following heart transplantation (HT). The aim of this study was to identify specific risk factors for early postoperative infections in HT ...
Risk Predictors in a Spanish Cohort With Cardiac Laminopathies. The REDLAMINA Registry
(Elsevier, 2020-06-29)
[Abstract]
Introduction and objectives.
According to sudden cardiac death guidelines, an implantable cardioverter-defibrillator (ICD) should be considered in patients with LMNA-related dilated cardiomyopathy (DCM) and ...