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Analysis of variants in the HCN4 gene and in three single nucleotide polymorphisms of the CYP3A4 gene for association with ivabradine reduction in heart rate: a preliminary report

Núñez, Lucía; Crespo-Leiro, María Generosa; Marrón Liñares, Grecia Manuela; Suárez-Fuentetaja, Natalia; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Grille Cancela, Zulaika; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Hermida-Prieto, Manuel (Via Médica, 2016)

[Abstract] Background: Ivabradine, a selective bradycardic drug, inhibits the If. In patients with heart failure (HF), ivabradine reduces the risk of rehospitalization and mortality. The average heart rate (HR) reduction ...

Polymorphisms in genes related to the complement system and antibody-mediated cardiac allograft rejection

Marrón Liñares, Grecia Manuela; Núñez, Lucía; Crespo-Leiro, María Generosa; Barge-Caballero, Eduardo; Pombo, Jorge; Paniagua-Martín, María J.; Suárez-Fuentetaja, Natalia; Cid, Javier; Grille Cancela, Zulaika; Muñiz, Javier; Tan, Carmela D.; Rene Rodríguez, E.; Vázquez-Rodríguez, José Manuel; Hermida-Prieto, Manuel (Elsevier, 2017-07-15)

[Abstract] Background. Heart transplantation (HT) is a life-saving treatment for patients with end-stage heart failure. One of the main problems after HT is the humoral response termed antibody-mediated rejection (AMR). ...

Prognostic value of serum lactate levels in patients undergoing urgent heart transplant: a subanalysis of the ASIS-TC spanish multicenter study

Couto-Mallón, David; González-Vílchez, Francisco; Almenar-Bonet, Luis; Díaz-Molina, Beatriz; Segovia-Cubero, Javier; González-Costello, José; Delgado-Jiménez, Juan; Castel-Lavilla, María A.; Crespo-Leiro, María Generosa; Rangel-Sousa, Diego; Martínez-Sellés, Manuel; Rábago-Juan-Aracil, Gregorio; De-la-Fuente Galán, Luis; Blasco-Peiró, Teresa; Hervás-Sotomayor, Daniela; Garrido-Bravo, Iris P.; Mirabet-Pérez, Sonia; Muñiz, Javier; Barge-Caballero, Eduardo (Elsevier, 2018-05-30)

[Abstract] Introduction and objectives. To study the prognostic value of serum lactate in patients under temporary preoperative mechanical circulatory support who underwent urgent heart transplant. Methods. We conducted ...

AGT haplotype in ITGA4 gene is related to antibody-mediated rejection in heart transplant patients

Núñez, Lucía; Marrón Liñares, Grecia Manuela; Crespo-Leiro, María Generosa; Barge-Caballero, Eduardo; Álvarez López, Eloy; Suárez Fuentetaja, Natalia; Paniagua Martín, María J.; Pombo, Jorge; Muñiz, Javier; Tan, Carmela D.; Rene Rodríguez, E.; Vázquez-Rodríguez, José Manuel (Stanislaw Stepkowski,, 2019-07-23)

[Abstract] Introduction. One of the main problems involved in heart transplantation (HT) is antibody-mediated rejection (AMR). Many aspects of AMR are still unresolved, including its etiology, diagnosis and treatment. ...

Do physicians correctly calculate thromboembolic risk scores?: a comparison of concordance between manual and computer‐based calculation of CHADS2 and CHA2DS2‐VASc scores

Esteve-Pastor, María Asunción; Marín, Francisco; Bertomeu-Martínez, Vicente; Roldán, Inmaculada; Cequier, Ángel; Badimón, Lina; Muñiz, Javier; Valdés, Mariano; Anguita, Manuel (Wiley, 2016-03-01)

[Abstract] BACKGROUND: Clinical risk scores, CHADS2 and CHA2 DS2 -VASc scores, are the established tools for assessing stroke risk in patients with atrial fibrillation (AF). AIM: The aim of this study is to assess concordance ...

Predictive value of the SAMe-TTR2R2 to predict quality of oral anticoagulation in atrial fibrillation: a prospective validation in the multicentre spanish observational registry FANTASIIA

Marín, Francisco; Roldán, Vanessa; Bertomeu-González, Vicente; Cequier, Ángel; Muñiz, Javier; Roldán, Inmaculada; Bertomeu-Martínez, Vicente; Badimón, Lina; Lip, Gregory Yoke Hong; Anguita, Manuel (Oxford, 2015)

Predictors of optimal pharmacological treatment in patients with heart failure and depressed ejection fraction. Results of the VIDA-IC study

Hidalgo Lesmes, Francisco José; Anguita, Manuel; Comín, Josep; Muñiz, Javier; Crespo-Leiro, María Generosa; Formiga, Francesc; Manzano, Luis; Almenar-Bonet, Luis; Frutos, Trinidad de (Wiley, 2015)

Prevalence of electrocardiographic findings associated to sudden cardiac death: spontaneous type 1 and type 2 Brugada patterns and QT disorders in spanish population older than forty years

Awamleh García, Paula; Graupner Abad, Catherine; Jiménez, R.M.; Talavera Calle, Pedro; Gómez Doblas, Juan J.; Muñiz, Javier; Alonso, J.J.; Roig, Eulàlia; Curcio Ruigómez, Alejandro; Serrano, J. (Oxford, 2015)

Influence of sex on long-term prognosis in patients with atrial fibrillation treated with oral anticoagulants. Results from the prospective, nationwide FANTASIIA study

Roldán Rabadán, Inmaculada; Esteve-Pastor, María Asunción; Anguita, Manuel; Muñiz, Javier; Ruiz Ortiz, Martín; Marín, Francisco; Roldán, Vanessa; Quesada, María Angustias; Camacho Siles, José; Cequier Fillat, Angel; Bertomeu-Martinez, Vicente; Martínez-Sellés, Manuel; Badimón, Lina (Elsevier, 2020-04-14)

[Abstract] Background: While many risk factors for Atrial Fibrillation (AF) have been identified, there are important differences in their relative impact between sexes. The aim of our study was to investigate the influence ...

Cancer incidence in heart transplant recipients with previous neoplasia history

Delgado-Jiménez, Juan F.; Alonso-Pulpón, Luis; Mirabet, Sonia; Almenar-Bonet, Luis; Villa, F.P.; González-Vílchez, Francisco; Palomo, J.; Blasco-Peiró, Teresa; García-Cosío, M. Dolores; González-Costello, José; De la Fuente-Galán, Luis; Rábago, Gregorio; Lage-Gallé, Ernesto; Pascual Figal, Domingo A.; Molina, B.D.; Arizón-del-Prado, José M.; Muñiz, Javier; Crespo-Leiro, María Generosa (Wiley, 2016-02-03)

[Abstract] Neoplasm history increases morbidity and mortality after solid organ transplantation and has disqualified patients from transplantation. Studies are needed to identify factors to be considered when deciding on ...

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