Buscar
Mostrando ítems 1-2 de 2
Association of accelerated dynamics of telomere sequence loss in peripheral blood leukocytes with incident knee osteoarthritis in Osteoarthritis Initiative cohort
(Nature, 2021-08-05)
[Abstract] Osteoarthritis (OA) is a chronic degenerative joint disease, being the main cause of laboral inability. Decreased telomere size in peripheral blood leukocytes (PBL) has been correlated with age-related pathologies, ...
Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy
(Elsevier, 2019-07-05)
[Abstract] Background. Ageing-related failure of homeostasis mechanisms contributes to articular cartilage degeneration and osteoarthritis (OA), for which disease-modifying treatments are not available. Our objective was ...