Mostrar o rexistro simple do ítem
Prediction of the response to photodynamic therapy in patients with chronic central serous chorioretinopathy based on optical coherence tomography using deep learning
dc.contributor.author | Fernández-Vigo, José Ignacio | |
dc.contributor.author | Gómez Calleja, Verónica | |
dc.contributor.author | Moura, Joaquim de | |
dc.contributor.author | Novo Buján, Jorge | |
dc.contributor.author | Burgos-Blasco, Barbara | |
dc.contributor.author | López-Guajardo, Lorenzo | |
dc.contributor.author | Donate-López, Juan | |
dc.contributor.author | Ortega Hortas, Marcos | |
dc.date.accessioned | 2024-07-05T16:38:14Z | |
dc.date.available | 2024-07-05T16:38:14Z | |
dc.date.issued | 2022-12 | |
dc.identifier.citation | Fernández-Vigo, J. I., Calleja, V. G., de Moura Ramos, J. J., Novo-Bujan, J., Burgos-Blasco, B., López-Guajardo, L., ... & Ortega-Hortas, M. (2022). Prediction of the response to photodynamic therapy in patients with chronic central serous chorioretinopathy based on optical coherence tomography using deep learning. Photodiagnosis and Photodynamic Therapy, 40, 103107. https://doi.org/10.1016/j.pdpdt.2022.103107 | es_ES |
dc.identifier.issn | 1572-1000 | |
dc.identifier.uri | http://hdl.handle.net/2183/37770 | |
dc.description | This version of the article has been accepted for publication in: Photodiagnosis and Photodynamic Therapy, 40, 103107. The Version of Record is available online at https://doi.org/10.1016/j.ins.2018.09.045 | es_ES |
dc.description.abstract | [Abstract]: Purpose To assess the prediction of the response to photodynamic therapy (PDT) in chronic central serous chorioretinopathy (CSCR) based on spectral-domain optical coherence tomography (SD-OCT) images using deep learning (DL). Methods Retrospective study including 216 eyes of 175 patients with CSCR and persistent subretinal fluid (SRF) who underwent half-fluence PDT. SD-OCT macular examination was performed before (baseline) and 3 months after treatment. Patients were classified into groups by experts based on the response to PDT: Group 1, complete SRF resorption (n = 100); Group 2, partial SRF resorption (n = 66); and Group 3, absence of any SRF resorption (n = 50). This work proposes different computational approaches: 1st approach compares all groups; 2nd compares groups 1 vs. 2 and 3 together; 3rd compares groups 2 vs. 3. Results The mean age was 55.6 ± 10.9 years and 70.3% were males. In the first approach, the algorithm showed a precision of up to 57% to detect the response to treatment in group 1 based on the initial scan, with a mean average accuracy of 0.529 ± 0.035. In the second model, the mean accuracy was higher (0.670 ± 0.046). In the third approach, the algorithm showed a precision of 0.74 ± 0.12 to detect the response to treatment in group 2 (partial SRF resolution) and 0.69 ± 0.15 in group 3 (absence of SRF resolution). Conclusion Despite the high clinical variability in the response of chronic CSCR to PDT, this DL algorithm offers an objective and promising tool to predict the response to PDT treatment in clinical practice. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Elsevier | es_ES |
dc.relation.uri | https://doi.org/10.1016/j.ins.2018.09.045 | es_ES |
dc.rights | Atribución-NoComercial-SinDerivadas 4.0 Internacional | es_ES |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/es/ | * |
dc.subject | Central serous chorioretinopathy | es_ES |
dc.subject | Photodynamic therapy | es_ES |
dc.subject | Deep learning | es_ES |
dc.subject | Optical Coherence Tomography | es_ES |
dc.title | Prediction of the response to photodynamic therapy in patients with chronic central serous chorioretinopathy based on optical coherence tomography using deep learning | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.access | info:eu-repo/semantics/openAccess | es_ES |
UDC.journalTitle | Photodiagnosis and Photodynamic Therapy | es_ES |
UDC.volume | 40 | es_ES |
UDC.issue | 103107 | es_ES |
UDC.startPage | 1 | es_ES |
UDC.endPage | 8 | es_ES |
dc.identifier.doi | 10.1016/j.pdpdt.2022.103107 |
Ficheiros no ítem
Este ítem aparece na(s) seguinte(s) colección(s)
-
GI-VARPA - Artigos [76]