Listar GI- NANOSELF4BIO - Artigos por autor "Fernández-Trillo, Paco"

Mostrando ítems 1-6 de 6

    • Aggregation of Vibrio cholerae by Cationic Polymers Enhances Quorum Sensing but Overrides Biofilm Dissipation in Response to Autoinduction 

      Creese, Oliver; Krachler, Anne Marie; Fernández-Trillo, Paco; Pérez-Soto, Nicolás (American Chemical Society, 2018)
      [Abstract] Vibrio cholerae is a Gram-negative bacterium found in aquatic environments and a human pathogen of global significance. Its transition between host-associated and environmental lifestyles involves the tight ...

    • Poly(Boc-acryloyl hydrazide): the importance of temperature and RAFT agent degradation on its preparation 

      Adoni, Pavan; Creese, Oliver; Su, Guanlong; Romanyuk, Andrey; Fernández-Trillo, Paco (Royal Society of Chemistry, 2019)
      [Abstract] Poly(acryloyl hydrazide) is a versatile polymer scaffold readily functionalised through post-polymerisation modification with aldehydes to yield polymers for biological applications. However, its polymerisation ...

    • Poly(triazolyl methacrylate) glycopolymers as potential targeted unimolecular nanocarriers 

      Madeira do O, J.; Foralosso, R.; Yilmaz, Gokhan; Mastrotto, Francesca; King, P.J.S.; Xerri, R. M.; He, Yinfeng; Walle, Christopher van der; Fernández-Trillo, Paco; Laughton, Charles; Styliari, Ioanna Danai; Stolnik, Snjezana Snow; Mantovani, Giuseppe (Royal Society of Chemistry, 2019)
      [Abstract] Synthetic glycopolymers are increasingly investigated as multivalent ligands for a range of biological and biomedical applications. This study indicates that glycopolymers with a fine-tuned balance between ...

    • Polymer-Induced Biofilms for Enhanced Biocatalysis 

      Adoni, Pavan; Romanyuk, Andrey; Overton, Tim W.; Fernández-Trillo, Paco (Royal Society of Chemistry, 2022-07-21)
      [Abstract] The intrinsic resilience of biofilms to environmental conditions makes them an attractive platform for biocatalysis, bioremediation, agriculture or consumer health. However, one of the main challenges in these ...

    • Site-Selective and Rewritable Labeling of DNA through Enzymatic, Reversible, and Click Chemistries 

      Fernández-Trillo, Paco; Wilkinson, Andrew A.; Neely, Robert; Jagu, Elodie; Ubych, Krystian; Coulthard, Steven; Rushton, Ashleigh; Kennefick, Jack; Su, Qiang (American Chemical Society, 2020)
      [Abstract] Current methods for bioconjugation rely on the introduction of stable linkers that lack the required versatility to perform sequential functionalizations. However, sequential manipulations are an increasing ...

    • Stimuli-Responsive Delivery of Antimicrobial Peptides Using Polyelectrolyte Complexes 

      Antropenko, Alexander; Caruso, Frank; Fernández-Trillo, Paco (Wiley, 2023)
      [Abstract] Antimicrobial peptides (AMPs) are antibiotics with the potential to address antimicrobial resistance. However, their translation to the clinic is hampered by issues such as off-target toxicity and low stability ...