Listar Nanochemistry and Self-Assembly for Biological Sciences (NANOSELF4BIO) por título
Mostrando ítems 15-34 de 45
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Gene-Activated Hyaluronic Acid-Based Cryogels for Cartilage Tissue Engineering
(Elsevier, 2023)[Abstract] Articular cartilage injuries are very frequent lesions that if left untreated may degenerate into osteoarthritis. Gene transfer to mesenchymal stem cells (MSCs) provides a powerful approach to treat these lesions ... -
Graphene for Implantable Biosensors
(Grupo Español del Carbón, 2021-06)[Abstract]: In this review, we will provide a comprehensive insight on the current research si-tuations and future challenges for the graphene-based implantable biosensors. We intro-duce the use of graphene derivatives for ... -
Graphene, Other Carbon Nanomaterials and the Immune System: Toward Nanoimmunity-By-Design
(IOP Publishing, 2020-07-13)[Abstract]: Carbon-based materials (CBMs), such as graphene, nanodiamonds, carbon fibers, and carbon dots, have attracted a great deal scientific attention due to their potential as biomedical tools. Following exposure, ... -
High-Yield Preparation of Exfoliated 1T-MoS2 with SERS Activity
(American Chemical Society, 2019-07-17)[Abstract]: Molybdenum disulfide (MoS2), a promising two-dimensional transition-metal dichalcogenide, presents a challenge in the tuning of its optoelectronic and chemical properties. Herein, we demonstrate an efficient ... -
Hydrogel-Guided, rAAV-Mediated IGF-I Overexpression Enables Long-Term Cartilage Repair and Protection against Perifocal Osteoarthritis in a Large-Animal Full-Thickness Chondral Defect Model at One Year In Vivo
(Wiley-VCH, 2021)[Abstract] The regeneration of focal articular cartilage defects is complicated by the reduced quality of the repair tissue and the potential development of perifocal osteoarthritis (OA). Biomaterial-guided gene therapy ... -
Improved Chondrogenic Differentiation of rAAV SOX9-Modified Human MSCs Seeded in Fibrin-Polyurethane Scaffolds in a Hydrodynamic Environment
(MDPI, 2018)[Abstract] The repair of focal articular cartilage defects remains a problem. Combining gene therapy with tissue engineering approaches using bone marrow-derived mesenchymal stem cells (MSCs) may allow the development of ... -
In Situ Synthesis of Artificial Lipids
(Elsevier, 2022-09-15)[Abstract] Lipids constitute one of the most enigmatic family of biological molecules. Although the importance of lipids as basic units of compartmental structure and energy storage is well-acknowledged, deciphering the ... -
Intrinsic and Selective Activity of Functionalized Carbon Nanotube/Nanocellulose Platforms Against Colon Cancer Cells
(Elsevier, 2022-01-25)[Abstract] Given their large surface area and versatile chemical reactivity, single-walled carbon nanotubes (SWCNTs) are regarded as the basis of new pharmacological complexes. In this study, SWCNTs are chemically ... -
Light-driven, heterogeneous organocatalysts for C–C bond formation toward valuable perfluoroalkylated intermediates
(American Association for the Advancement of Science, 2020-11-11)The favorable exploitation of carbon nitride (CN) materials in photocatalysis for organic synthesis requires the appropriate fine-tuning of the CN structure. Here, we present a deep investigation of the structure/activity ... -
Mass Spectrometry of Carbohydrate-Protein Interactions on a Glycan Array Conjugated to CVD Graphene Surfaces
(IOP, 2020-01-06)[Abstract]: Mass spectrometry (MS) is a valuable tool for functional genomic, proteomic, and glycomic studies. In particular, the combination of MS with microarrays is a powerful technique for analyzing the activity of ... -
Metal Nanoparticles/MoS2 Surface-Enhanced Raman Scattering- Based Sandwich Immunoassay for α‑Fetoprotein Detection
(American Chemical Society, 2021-02-13)[Abstract]: The detection of cancer biomarkers at an early stage of tumor development is vital for effective diagnosis and treatment of cancer. Current diagnostic tools can often detect cancer only when the biomarker levels ... -
Metal-Free Photocatalysis: Two-Dimensional Nanomaterial Connection toward Advanced Organic Synthesis
(American Chemical Society, 2021-03-21)[Abstract] Two-dimensional (2D) nanostructures are a frontier in materials chemistry as a result of their extraordinary properties. Metal-free 2D nanomaterials possess extra appeal due to their improved cost-effectiveness ... -
Microwave-Induced Covalent Functionalization of Few-Layer Graphene with Arynes under Solvent-Free Conditions
(Royal Society of Chemistry, 2018-07-04)[Abstract]: A non-conventional modification of exfoliated few-layer graphene (FLG) with different arynes under microwave (MW) irradiation and solvent-free conditions is reported. The described approach allows reaching fast, ... -
Multifunctional graphene quantum dots: A therapeutic strategy for neurodegenerative diseases by regulating calcium influx, crossing the blood-brain barrier and inhibiting Aβ-protein aggregation
(Elsevier, 2024)[Abstract] Multifunctional nanoparticles could be the hallmark for the treatment of neurodegenerative diseases. Dissociation of protein aggregates causing neuronal damage and transfer of specific drugs which can downregulate ... -
Non-viral Gene Delivery to Human Mesenchymal Stem Cells: A Practical Guide Towards Cell Engineering
(BioMed Central, 2023)[Abstract] In recent decades, human mesenchymal stem cells (hMSCs) have gained momentum in the field of cell therapy for treating cartilage and bone injuries. Despite the tri-lineage multipotency, proliferative properties, ... -
‘One-pot’ engineering of 0D carbon-based inorganic nanoarchitectonics for boosting multitasking catalytic activity
(Elsevier, 2024)[Abstract] Easy-to-make nanostructured materials that exhibit multitasking activity —while reducing the use of hazardous solvents throughout its architectural design— is a must to advance in the so-called Industry 4.0. ... -
Organotin(IV)-Decorated Graphene Quantum Dots as Dual Platform for Molecular Imaging and Treatment of Triple Negative Breast Cancer
(Wiley, 2023)[ Abstract] The pharmacological activity of organotin(IV) complexes in cancer therapy is well recognized but their large applicability is hampered by their poor water solubility. Hence, carbon dots, in particular nitrogen-doped ... -
Poly(Boc-acryloyl hydrazide): the importance of temperature and RAFT agent degradation on its preparation
(Royal Society of Chemistry, 2019)[Abstract] Poly(acryloyl hydrazide) is a versatile polymer scaffold readily functionalised through post-polymerisation modification with aldehydes to yield polymers for biological applications. However, its polymerisation ... -
Poly(triazolyl methacrylate) glycopolymers as potential targeted unimolecular nanocarriers
(Royal Society of Chemistry, 2019)[Abstract] Synthetic glycopolymers are increasingly investigated as multivalent ligands for a range of biological and biomedical applications. This study indicates that glycopolymers with a fine-tuned balance between ... -
Polymer-Induced Biofilms for Enhanced Biocatalysis
(Royal Society of Chemistry, 2022-07-21)[Abstract] The intrinsic resilience of biofilms to environmental conditions makes them an attractive platform for biocatalysis, bioremediation, agriculture or consumer health. However, one of the main challenges in these ...