Listar GI - NANOTOXGEN - Artigos por título
Mostrando ítems 8-27 de 33
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DNA Damage in Circulating Leukocytes Measured With the Comet Assay May Predict the Risk of Death
(2021)[Abstract] The comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human populations. To estimate the risk of overall mortality, ... -
Effects of Zinc Oxide Nanoparticle Exposure on Human Glial Cells and Zebrafish Embryos
(MDPI, 2023-08-01)[Abstract] Zinc oxide nanoparticles (ZnO NPs) are among the most widely used nanomaterials. They have multiple applications in cosmetics, textiles, paints, electronics and, recently, also in biomedicine. This extensive use ... -
Endocrine and Immunological Parameters in Individuals Involved in Prestige Spill Cleanup Tasks Seven Years After the Exposure
(Elsevier, 2013-06-20)[Abstract] In November 2002 the oil tanker Prestige spilled 63,000tonnes of heavy oil off the northwest coast of Spain, impacting more than 1000km of coastline. A general concern led to a huge mobilization of human and ... -
Evaluation of Okadaic Acid-Induced Genotoxicity in Human Cells Using the Micronucleus Test and γH2AX Analysis
(Taylor and Francis, 2011-06-27)[Abstract] Marine algal blooms have become a public health concern due to increasing frequency in the environment and severity of exposure consequences. Human intoxications produced by phycotoxins occur globally through ... -
Exploring Early Detection of Frailty Syndrome in Older Adults: Evaluation of Oxi-Immune Markers, Clinical Parameters and Modifiable Risk Factors
(2021)[Abstract] Ageing is accompanied with a decline in several physiological systems. Frailty is an age-related syndrome correlated to the loss of homeostasis and increased vulnerability to stressors, which is associated with ... -
First Iron(II) Organometallic Compound Acting as ABCB1 Inhibitor
(Elsevier, 2023-05-13)[Abstract] Five new iron (II) complexes bearing imidazole-based (Imi-R) ligands with the general formula [Fe(η5-C5H5)(CO)(PPh3)(Imi-R)][CF3SO3] were synthesized and fully characterized by several spectroscopic and analytical ... -
Identification of Differentially Expressed Genes in SHSY5Y Cells Exposed to Okadaic Acid by Suppression Subtractive Hybridization
(Springer Nature, 2012-01-27)[Abstract] Background: Okadaic acid (OA), a toxin produced by several dinoflagellate species is responsible for frequent food poisonings associated to shellfish consumption. Although several studies have documented the OA ... -
Induction of Oxidative DNA Damage by the Marine Toxin Okadaic Acid Depends on Human Cell Type
(Elsevier, 2011-03-01)[Abstract] The marine toxin okadaic acid (OA) is the main representative of diarrhoeic shellfish poisoning (DSP) toxins. Its ingestion induces nausea, vomiting, diarrhoea and abdominal ache. It has also been found to trigger ... -
Inter-Laboratory Variation in DNA Damage Using a Standard Comet Assay Protocol
(Oxford University Press, 2012-07-27)[Abstract] There are substantial inter-laboratory variations in the levels of DNA damage measured by the comet assay. The aim of this study was to investigate whether adherence to a standard comet assay protocol would ... -
Iron(II)-cyclopentadienyl compounds are cytotoxic against colon adenocarcinoma cell lines: Ethylenebis(diphenylphosphane) vs. triphenylphosphane
(Elsevier, 2023)[Abstract] Structure-activity studies aiming to understand the role of each coligand in the formulation of new metallodrugs is an important subject. In that frame, six new compounds with general formula [Fe(η5-C5H5)(dppe ... -
Mononuclear/Binuclear [VIVO]/[VVO2] Complexes Derived from 1,3-Diaminoguanidine and Their Catalytic Application for the Oxidation of Benzoin via Oxygen Atom Transfer
(ACS, 2023-01-10)[Abstract] Ligands H4sal-dag (I) and H4Brsal-dag (II) derived from 1,3-diaminoguanidine and salicylaldehyde or 5-bromosalicylaldehyde react with one or 2 mol equivalent of vanadium precursor to give two different series ... -
Neuronal Cytotoxicity and Genotoxicity Induced by Zinc Oxide Nanoparticles
(Elsevier, 2013-03-26)[Abstract] Zinc oxide nanoparticles (ZnO NPs) are one of the most abundantly used nanomaterials in consumer products and biomedical applications. As a result, human exposure to these NPs is highly frequent and they have ... -
Okadaic Acid Induces Morphological Changes, Apoptosis and Cell Cycle Alterations in Different Human Cell Types
(Royal Society of Chemistry (Gran Bretaña), 2011-03-28)[Abstract] Okadaic acid (OA) is a marine toxin produced by dinoflagellate species which is frequently accumulated in molluscs usual in the human diet. The exact action mechanism of OA has not been described yet and the ... -
Polymer-Supported Oxidovanadium(IV) Complexes and Their Catalytic Applications in One-Pot Multicomponent Reactions Producing Biologically Active 2,4,5-Trisubstituted-1H-imidazoles
(MDPI, 2023-03-19)[Abstract] Two new monobasic tridentate O⁀N⁀N donor ligands, HL1 (I) and HL2 (II) have been obtained in two steps by reacting phenylhydrazine and salicylaldehyde or 3,5-di-tert-butylsalicylaldehyde and then reacting the ... -
Salivary Leucocytes as In Vitro Model to Evaluate Nanoparticle-Induced DNA Damage
(MDPI, 2021-07-27)[Abstract] Metal oxide nanoparticles (NPs) have a wide variety of applications in many consumer products and biomedical practices. As a result, human exposure to these nanomaterials is highly frequent, becoming an issue ... -
Sequence characterization of the 5S ribosomal DNA and the internal transcribed spacer (ITS) region in four European Donax species (Bivalvia: Donacidae)
(BioMed Central, 2018)[Abstract] Background: The whole repeat unit of 5S rDNA and the internal transcribed spacer (ITS) of four European Donax species were analysed. After amplifying, cloning and sequencing several 5S and ITS units, their basic ... -
Solution-State Cooperative Luminescence Upconversion in Molecular Ytterbium Dimers
(Wiley, 2023)[Abstract] Two homometallic ytterbium dimers are prepared and their solution-state photoluminescence and upconversion properties are investigated. Both complexes exhibit two-photon cooperative luminescence upconversion in ... -
Suitability of Salivary Leucocytes to Assess DNA Repair Ability in Human Biomonitoring Studies by the Challenge-Comet Assay
(Elsevier, 2022)[Abstract] The challenge-comet assay is a simple but effective approach that provides a quantitative and functional determination of DNA repair ability, and allows to monitor the kinetics of repair process. Peripheral blood ... -
Suitability of the In Vitro Cytokinesis-Block Micronucleus Test for Genotoxicity Assessment of TiO2 Nanoparticles on SH-SY5Y Cells
(2021)[Abstract] Standard toxicity tests might not be fully adequate for evaluating nanomaterials since their unique features are also responsible for unexpected interactions. The in vitro cytokinesis-block micronucleus (CBMN) ...