Light-Emitting Probes for Labeling Peptides
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Light-Emitting Probes for Labeling PeptidesAuthor(s)
Date
2020-11-25Citation
Boaro, A., Ageitos, L., Torres, M., Bartoloni, F.H., and de la Fuente-Nunez, C. (2020). Light-Emitting Probes for Labeling Peptides. Cell Reports Phys. Sci. 1, 100257
Abstract
[Abstract] Peptides are versatile biopolymers composed of 2–100 amino acid residues that present a wide range of biological functions and constitute potential therapies for numerous diseases, partly due to their ability to penetrate cell membranes. However, their mechanisms of action have not been fully elucidated due to the lack of appropriate tools. Existing light-emitting probes are limited by their cytotoxicity and large size, which can alter peptide structure and function. Here, we describe the available fluorescent, bioluminescent, and chemiluminescent probes for labeling peptides, with a focus on minimalistic options.
Keywords
Peptides
Fluorescent probes
Labeling
Imaging
Fluorescent probes
Labeling
Imaging
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Rights
Atribución-NoComercial-SinDerivadas 4.0 Internacional
ISSN
2666-3864