Now showing items 1-20 of 98

    • A meta-analysis and a functional study support the influence of mtDNA variant m.16519C on the risk of rapid progression of knee osteoarthritis 

      Durán-Sotuela, Alejandro; Fernández-Moreno, Mercedes; Suárez-Ulloa, Victoria; Vázquez-García, Jorge; Relaño, Sara; Hermida-Gómez, Tamara; Balboa-Barreiro, Vanesa; Lourido-Salas, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Ruiz-Romero, Cristina; Fernández-Tajes, Juan; Vaamonde-García, Carlos; de Andrés, María C.; Oreiro, Natividad; Blanco García, Francisco J; Rego-Pérez, Ignacio (BMJ, 2023-04-06)
      [Abstract] Objectives: To identify mitochondrial DNA (mtDNA) genetic variants associated with the risk of rapid progression of knee osteoarthritis (OA) and to characterise their functional significance using a cellular ...
    • Advanced maternal age as an obstetric risk factor: current experience in a hospital from northwestern Spain 

      Peteiro Mahía, Laura; Blanco López, Susana; López Castiñeira, Noelia; Navas Arrebola, Rocío; Seoane-Pillado, Teresa; Pértega-Díaz, Sonia (Ordem dos Médicos, 2022-03-14)
      [Abstract] Introduction: Studies updating the evidence in advanced maternal age as an independent factor of obstetric risk are needed. The aim of this study was to determine the prevalence of ≥ 35-years-old pregnant women ...
    • All-trans retinoic acid inhibits migration and invasiveness of rheumatoid fibroblast-like synoviocytes 

      Rodríguez Trillo, Ángela; Blanco García, Francisco J; Mera-Varela, Antonio; González, Antonio; Conde, Carmen; Mosquera, Nerea (American Society for Pharmacology and Experimental Therapeutics (ASPET), 2020-02)
      [Abstract] Fibroblast-like synoviocytes (FLSs) are pivotal in inflammation and joint damage of rheumatoid arthritis (RA). They acquire an active and aggressive phenotype, displaying increased migration and invasiveness and ...
    • An atlas of the knee joint proteins and their role in osteoarthritis defined by literature mining 

      Paz-González, Rocío; Lourido, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Quaranta, Patricia; Picchi, Florencia; Blanco García, Francico J; Ruiz-Romero, Cristina (Elsevier, 2023-08)
      [Abstract] Osteoarthritis (OA) is the most prevalent rheumatic pathology. However, OA is not simply a process of wear and tear affecting articular cartilage but rather a disease of the entire joint. One of the most common ...
    • Anti-inflammatory activity of APPA (Apocynin and Paeonol) in human articular chondrocytes 

      Fernández-Moreno, Mercedes; Hermida-Gómez, Tamara; Larkins, Nicholas; Reynolds, Alan; Blanco García, Francico J (MDPI, 2024-01-16)
      [Abstract] Osteoarthritis (OA) is a chronic joint disease leading to cartilage loss and reduction in the joint space which results in pain. The current pharmacological treatment of OA is inadequate and pharmacological ...
    • Anti-inflammatory potential of ulvan 

      Flórez-Fernández, Noelia; Rodríguez-Coello, Arianna; Latire, Thomas; Bourgougnon, Natalie; Torres, María Dolores; Buján, Manuela; Muíños, Alexandra; Muíños, Antonio; Meijide-Faílde, Rosa; Blanco García, Francico J; Vaamonde-García, Carlos; Domínguez, Herminia (Elsevier, 2023-12-31)
      [Abstract] Green seaweeds are a widespread group of marine macroalgae that could be regarded as biorenewable source of valuable compounds, in particular sulfated polysaccharides like ulvans with interesting biological ...
    • Antifibrotic effect of brown algae-derived fucoidans on osteoarthritic fibroblast-like synoviocytes 

      Piñeiro-Ramil, María; Flórez-Fernández, Noelia; Ramil-Gómez, Olalla; Torres, María Dolores; Domínguez, Herminia; Blanco García, Francisco J; Meijide-Faílde, Rosa; Vaamonde-García, Carlos (Elsevier, 2022-01-12)
      [Abstract] Synovial fibrosis is a pathological process which contributes to joint pain and stiffness in several musculoskeletal disorders. Fucoidans, sulfated polysaccharides found in brown algae, have recently emerged as ...
    • Anxiety in the perinatal period: associated factors 

      Navas Arrebola, Rocío; Blanco López, Susana; Peteiro Mahía, Laura; López Castiñeira, Noelia; Pértega-Díaz, Sonia; Seoane-Pillado, Teresa (IMR Press, 2024-03-19)
      [Abstract] Background: Attention to mothers during pregnancy, childbirth, and postpartum has focused on the physical aspects, overlooking mental health, which is critical to maternal well-being and childbirth. The aim of ...
    • Association Foot Morphology and Performance in Rhythmic Gymnastics 

      Sierra Palmeiro, Elena; Bobo-Arce, Marta; Fernández-Villarino, María A.; Alonso-Tajes, Francisco; González-Martín, M. Carmen; Gómez-Rivas, Lucía (Universidad Autónoma de Madrid, 2020)
      [Abstract] The objectives of the study were to determine the influence of foot morphology on performance in Rhythmic Gymnastics and to analyze the influence of years of practice. The sample consisted of 48 gymnasts who ...
    • Association of accelerated dynamics of telomere sequence loss in peripheral blood leukocytes with incident knee osteoarthritis in Osteoarthritis Initiative cohort 

      Guillén, Rebeca; Otero, Fátima; Mosquera, Alejandro; Vázquez-Mosquera, María E.; Rego-Pérez, Ignacio; Blanco García, Francisco J; Fernández, José Luis (Nature, 2021-08-05)
      [Abstract] Osteoarthritis (OA) is a chronic degenerative joint disease, being the main cause of laboral inability. Decreased telomere size in peripheral blood leukocytes (PBL) has been correlated with age-related pathologies, ...
    • Association of rhinitis with asthma prevalence and severity 

      Acevedo-Prado, Antonio; Seoane-Pillado, Teresa; López-Silvarrey-Varela, Ángel; Salgado, Francisco-Javier; Cruz, María-Jesús; Faraldo-García, A.; Nieto-Fontarigo, Juan-José; Pértega-Díaz, Sonia; Sánchez-Lastres, J.; San-José-González, Miguel-Ángel; Bamonde-Rodríguez, Luis; Garnelo-Suárez, Luciano; Pérez-Castro, Teresa-Rosalía; Sampedro-Campos, Manuel; González-Barcala, Francisco-Javier (Nature, 2022-04-16)
      [Abstract] Asthma and rhinitis often co-exist in the same patient. Although some authors observed a higher prevalence and/or greater severity of asthma in patients with rhinitis, this view is not homogeneous and the debate ...
    • Awake prone decubitus positioning in COVID-19 patients: a systematic review and metaanalysis 

      García, Agustín; Galeiras, Rita; Pértega-Díaz, Sonia (Sciendo, 2023-05-08)
      [Abstract] To date, recommendations for the implementation of awake prone positioning in patients with hypoxia secondary to SARSCoV2 infection have been extrapolated from prior studies on respiratory distress. Thus, we ...
    • Colorectal cancer recurrence and its impact on survival after curative surgery: an analysis based on multistate models 

      Balboa-Barreiro, Vanesa; Pértega-Díaz, Sonia; García-Rodríguez, Teresa; González-Martín, Cristina; Pardeiro-Pértega, Remedios; Yáñez-González-Dopeso, Loreto; Seoane-Pillado, Teresa (Elsevier, 2023-12-11)
      [Abstract] Aim: To investigate the usefulness of multistate models (MSM) for determining colorectal cancer (CRC) recurrence rate, to analyse the effect of different factors on tumour recurrence and death, and to assess the ...
    • Complicaciones y grado de dificultad de la intubación orotraqueal en la unidad de cuidados intensivos pre-post instauración de un protocolo de intubación para el paciente crítico: estudio prospectivo y observacional 

      Taboada, M.; Almeida, X.; Cariñena, A.; Costa, J.; Carmona-Monge, J.; Agilda, A.; Barreiro, L.; Castillo, J.; Williams, K.; Segurola, J.; Álvarez, J.; Seoane-Pillado, Teresa (Elsevier, 2023-11-07)
      [Resumen] Objetivo. El objetivo de nuestro estudio fue comparar el grado de dificultad y las complicaciones relacionadas con la intubación orotraqueal en una unidad de cuidados intensivos (UCI), pre y post instauración de ...
    • Concordance between pressure platform and pedigraph 

      González-Martin, Cristina; Fernández-López, Uxía; Mosquera-Fernández, Abián; Balboa-Barreiro, Vanesa; García-Rodríguez, María Teresa; Seijo-Bestilleiro, Rocío; Veiga-Seijo, Raquel (MDPI, 2021-12-09)
      [Abstract] Objectives: Determine the concordance between two methods of obtaining the plantar footprint (pedigraph and pressure platform). Methods: A descriptive, cross-sectional, observational study of prevalence was ...
    • Concordance between the Different Cardiovascular Risk Scores in People with Rheumatoid Arthritis and Psoriasis Arthritis 

      González-Martín, Cristina; Grande Morais, Silvia; Pértega-Díaz, Sonia; Seoane-Pillado, Teresa; Balboa-Barreiro, Vanesa; Veiga-Seijo, Raquel (Hindawi, 2019-03-14)
      [Abstract] Aim. To determine the cardiovascular risk and the concordance between the different scores in people with rheumatoid arthritis (RA) and psoriatic arthritis (PsA). Methods. Observational descriptive study of ...
    • Cone-Beam CT-Guided Lung Biopsies: Results in 94 Patients 

      Gulías Soidán, Daniel; Crus-Sánchez, Nilfa Milena; Fraga-Manteiga, Daniel; Cao-González, Juan Ignacio; Balboa-Barreiro, Vanesa; González-Martín, Cristina (MDPI, 2020-12-10)
      [Abstract] Background: The aim of this study was to evaluate the diagnostic capacity of Cone-Beam computed tomography (CT)-guided transthoracic percutaneous biopsies on lung lesions in our setting and to detect risk factors ...
    • Critical patients COVID-19 has changed the management and outcomes in the ICU after 1 year of the pandemic?: a multicenter, prospective, observational study 

      Rama-Maceiras, Pablo; Sanduende, Yolanda; Taboada, Manuel; Casero, María; Leal, Sonsoles; Pita-Romero, Rafael; Fernández, Ricardo; López, Eva; López, José Antonio; Pita, Elvira; Tubío, Ana; Rodríguez, Arancha; Varela, Marina; Campaña, Daniel; Delgado, Carla; Lombardía, Mónica; Villar, Eva; Blanco, Pilar; Martínez, Adrián; Sarmiento, Ana; Díaz, Pilar; Ojea, María; Rodríguez, Ángel; Mouriz, Lorena; Cid, Milagros; Ramos, Lorena; Seoane-Pillado, Teresa (Elsevier, 2023-02)
      [Abstract] Objective: To compare the clinical characteristics, treatments, and evolution of critical patients with COVID-19 pneumonia treated in intensive care units (ICU) after one year of pandemic. Methodology: ...
    • Current experience with obstetrical events: characteristics and the effects of nocturnal periods 

      Blanco López, Susana; Peteiro Mahía, Laura; Navas Arrebola, Rocío; López Castiñeira, Noelia; Pértega-Díaz, Sonia; Seoane-Pillado, Teresa (IMR Press, 2024-03-25)
      [Abstract] Background: The object is to analyze the influence of the nocturnal period and lunar phases on the frequency of obstetrical events in pregnant women. Methods: This was a retrospective, transversal observational ...
    • Dermatological Diseases in Seamen’s Lower Extremity: A Prevalence Study 

      Rego, Vanesa; Gómez-Muniz, Fernando; Bouza Prego, Mª Ángeles; Veiga-Seijo, Raquel (Vía Médica, 2021-03)
      [Abstract] Background: Little is known about the impact of occupational seafaring on lower limb conditions. The aim of the study was to estimate the prevalence of dermatological diseases affecting the feet and lower ...