• An atlas of the knee joint proteins and their role in osteoarthritis defined by literature mining 

      Paz-González, Rocío; Lourido, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Quaranta, Patricia; Picchi, Florencia; Blanco García, Francico J; Ruiz-Romero, Cristina (Elsevier, 2023-08)
      [Abstract] Osteoarthritis (OA) is the most prevalent rheumatic pathology. However, OA is not simply a process of wear and tear affecting articular cartilage but rather a disease of the entire joint. One of the most common ...
    • Mitochondrial dysfunction and oxidative stress in rheumatoid arthritis 

      López-Armada, María José; Fernández-Rodríguez, Jennifer Adriana; Blanco García, Francisco J (MDPI, 2022-06-12)
      [Abstract] Control of excessive mitochondrial oxidative stress could provide new targets for both preventive and therapeutic interventions in the treatment of chronic inflammation or any pathology that develops under an ...
    • Mitochondrial genetics and epigenetics in osteoarthritis 

      Rego-Pérez, Ignacio; Durán-Sotuela, Alejandro; Ramos-Louro, Paula; Blanco García, Francisco J (Frontiers, 2020-01-17)
      [Abstract] During recent years, the significant influence of mitochondria on osteoarthritis (OA), the most common joint disease, has been consistently demonstrated. Not only mitochondrial dysfunction but also mitochondrial ...
    • Mitochondrial role on cellular apoptosis, autophagy, and senescence during osteoarthritis pathogenesis 

      Dalmao-Fernández, Andrea; Hermida-Gómez, Tamara; Nogueira-Recalde, Uxía; Rego-Pérez, Ignacio; Blanco García, Francisco J; Fernández-Moreno, Mercedes (MDPI, 2024-06-04)
      [Abstract] Authors have demonstrated that apoptosis activation is a pathway related to cartilage degradation characteristics of the OA process. Autophagy is an adaptive response to protect cells from various environmental ...
    • Oleate prevents palmitate-induced mitochondrial dysfunction in chondrocytes 

      Vázquez-Mosquera, María E.; Fernández-Moreno, Mercedes; Cortés-Pereira, Estefanía; Relaño, Sara; Dalmao-Fernández, Andrea; Ramos-Louro, Paula; Durán Sotuela, Alejandro; Rego-Pérez, Ignacio; Blanco García, Francisco J (Frontiers, 2021-06-15)
      [Abstract] The association between obesity and osteoarthritis (OA) in joints not subjected to mechanical overload, together with the relationship between OA and metabolic syndrome, suggests that there are systemic factors ...