Listar Grupo de Investigación en Reumatoloxía e Saúde (GIR-S) por autor "Ruiz-Romero, Cristina"

Mostrando ítems 1-5 de 5

    • A meta-analysis and a functional study support the influence of mtDNA variant m.16519C on the risk of rapid progression of knee osteoarthritis 

      Durán-Sotuela, Alejandro; Fernández-Moreno, Mercedes; Suárez-Ulloa, Victoria; Vázquez-García, Jorge; Relaño, Sara; Hermida-Gómez, Tamara; Balboa-Barreiro, Vanesa; Lourido-Salas, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Ruiz-Romero, Cristina; Fernández-Tajes, Juan; Vaamonde-García, Carlos; de Andrés, María C.; Oreiro, Natividad; Blanco García, Francisco J; Rego-Pérez, Ignacio (BMJ, 2023-04-06)
      [Abstract] Objectives: To identify mitochondrial DNA (mtDNA) genetic variants associated with the risk of rapid progression of knee osteoarthritis (OA) and to characterise their functional significance using a cellular ...

    • An atlas of the knee joint proteins and their role in osteoarthritis defined by literature mining 

      Paz-González, Rocío; Lourido, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Quaranta, Patricia; Picchi, Florencia; Blanco García, Francico J; Ruiz-Romero, Cristina (Elsevier, 2023-08)
      [Abstract] Osteoarthritis (OA) is the most prevalent rheumatic pathology. However, OA is not simply a process of wear and tear affecting articular cartilage but rather a disease of the entire joint. One of the most common ...

    • Exploring high-throughput immunoassays for biomarker validation in rheumatic diseases in the context of the human proteome project 

      Fuentes, Manuel; Ruiz-Romero, Cristina; Misiego, Sara; Juanes-Velasco, Pablo; Landeira-Viñuela, Alicia; Torres-Roda, Adrián; Lorenzo-Gil, Héctor; González-González, María; Hernández, Ángela P.; Lourido, Lucía; Sjöberg, Ronald; Pin, Elisa; Las Rivas, Javier de; Sánchez-Santos, José Manuel; Nilsson, Peter; Blanco García, Francisco J (ACS Publications, 2022-12-07)
      [Abstract] Rheumatic diseases are high prevalence pathologies with different etiology and evolution and low sensitivity in clinical diagnosis. Therefore, it is necessary to develop an early diagnosis method which allows ...

    • Identification of a distinct lipidomic profile in the osteoarthritic synovial membrane by mass spectrometry imaging 

      Rocha Loureda, Beatriz; Cillero-Pastor, B.; Ruiz-Romero, Cristina; Paine, Martin R.L.; Cañete, Juan D.; Heeren, Ron M.A.; Blanco García, Francisco J (Elsevier, 2021-05)
      [Abstract] Objective: Synovial inflammation is one of the most characteristic events in different types of arthritis, including Osteoarthritis (OA). Emerging evidence also suggests the involvement of lipids in the regulation ...

    • Prognostic model to predict the incidence of radiographic knee osteoarthritis 

      Paz-González, Rocío; Balboa-Barreiro, Vanesa; Lourido, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Oreiro, Natividad; Ruiz-Romero, Cristina; Blanco García, Francico J (BMJ, 2024-01-05)
      [Abstract] Objective: Early diagnosis of knee osteoarthritis (KOA) in asymptomatic stages is essential for the timely management of patients using preventative strategies. We develop and validate a prognostic model useful ...