Listar Grupo de Investigación en Reumatoloxía e Saúde (GIR-S) por autor "Oreiro, Natividad"
Mostrando ítems 1-5 de 5
-
A meta-analysis and a functional study support the influence of mtDNA variant m.16519C on the risk of rapid progression of knee osteoarthritis
Durán-Sotuela, Alejandro; Fernández-Moreno, Mercedes; Suárez-Ulloa, Victoria; Vázquez-García, Jorge; Relaño, Sara; Hermida-Gómez, Tamara; Balboa-Barreiro, Vanesa; Lourido-Salas, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Ruiz-Romero, Cristina; Fernández-Tajes, Juan; Vaamonde-García, Carlos; de Andrés, María C.; Oreiro, Natividad; Blanco García, Francisco J; Rego-Pérez, Ignacio (BMJ, 2023-04-06)[Abstract] Objectives: To identify mitochondrial DNA (mtDNA) genetic variants associated with the risk of rapid progression of knee osteoarthritis (OA) and to characterise their functional significance using a cellular ... -
Metabolic syndrome is not associated with erosive hand osteoarthritis: a cross-sectional study using data from the PROCOAC cohort
Silva-Díaz, Maite; Pértega-Díaz, Sonia; Balboa-Barreiro, Vanesa; Tilve-Álvarez, Carlos M.; Raga-Sivira, Ana; Rego-Pérez, Ignacio; Blanco García, Francisco J; Oreiro, Natividad (Springer Nature, 2024-03-12)[Abstract] To delineate the phenotype of erosive hand osteoarthritis (EHOA) in a Spanish population and assess its correlation with metabolic syndrome. We conducted a cross-sectional study using baseline data from the ... -
Mitonuclear epistasis involving TP63 and haplogroup Uk: risk of rapid progression of knee OA in patients from the OAI
Durán-Sotuela, Alejandro; Oreiro, Natividad; Fernández-Moreno, Mercedes; Vázquez-García, Jorge; Relaño-Fernández, Sara; Balboa-Barreiro, Vanesa; Blanco García, Francisco J; Rego-Pérez, Ignacio (Elsevier, 2024-01-06)[Abstract] Objective: To investigate genetic interactions between mitochondrial deoxyribonucleic acid (mtDNA) haplogroups and nuclear single nucleotide polymorphisms (nSNPs) to analyze their impact on the development ... -
Optical biomarkers for the diagnosis of osteoarthritis through Raman spectroscopy: radiological and biochemical validation using ex vivo human cartilage samples
Casal-Beiroa, Paula; Balboa-Barreiro, Vanesa; Oreiro, Natividad; Pértega-Díaz, Sonia; Blanco García, Francisco J; Magalhaes, Joana (MDPI, 2021-03-18)[Abstract] Osteoarthritis (OA) is the most common rheumatic disease, characterized by progressive articular cartilage degradation. Raman spectroscopy (RS) has been recently proposed as a label-free tool to detect molecular ... -
Prognostic model to predict the incidence of radiographic knee osteoarthritis
Paz-González, Rocío; Balboa-Barreiro, Vanesa; Lourido, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Oreiro, Natividad; Ruiz-Romero, Cristina; Blanco García, Francico J (BMJ, 2024-01-05)[Abstract] Objective: Early diagnosis of knee osteoarthritis (KOA) in asymptomatic stages is essential for the timely management of patients using preventative strategies. We develop and validate a prognostic model useful ...