Listar Grupo de Investigación en Reumatoloxía e Saúde (GIR-S) por autor "Durán-Sotuela, Alejandro"
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A meta-analysis and a functional study support the influence of mtDNA variant m.16519C on the risk of rapid progression of knee osteoarthritis
Durán-Sotuela, Alejandro; Fernández-Moreno, Mercedes; Suárez-Ulloa, Victoria; Vázquez-García, Jorge; Relaño, Sara; Hermida-Gómez, Tamara; Balboa-Barreiro, Vanesa; Lourido-Salas, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Ruiz-Romero, Cristina; Fernández-Tajes, Juan; Vaamonde-García, Carlos; de Andrés, María C.; Oreiro, Natividad; Blanco García, Francisco J; Rego-Pérez, Ignacio (BMJ, 2023-04-06)[Abstract] Objectives: To identify mitochondrial DNA (mtDNA) genetic variants associated with the risk of rapid progression of knee osteoarthritis (OA) and to characterise their functional significance using a cellular ... -
Mitochondrial genetics and epigenetics in osteoarthritis
Rego-Pérez, Ignacio; Durán-Sotuela, Alejandro; Ramos-Louro, Paula; Blanco García, Francisco J (Frontiers, 2020-01-17)[Abstract] During recent years, the significant influence of mitochondria on osteoarthritis (OA), the most common joint disease, has been consistently demonstrated. Not only mitochondrial dysfunction but also mitochondrial ...