• An atlas of the knee joint proteins and their role in osteoarthritis defined by literature mining 

      Paz-González, Rocío; Lourido, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Quaranta, Patricia; Picchi, Florencia; Blanco García, Francico J; Ruiz-Romero, Cristina (Elsevier, 2023-08)
      [Abstract] Osteoarthritis (OA) is the most prevalent rheumatic pathology. However, OA is not simply a process of wear and tear affecting articular cartilage but rather a disease of the entire joint. One of the most common ...
    • Anti-inflammatory activity of APPA (Apocynin and Paeonol) in human articular chondrocytes 

      Fernández-Moreno, Mercedes; Hermida-Gómez, Tamara; Larkins, Nicholas; Reynolds, Alan; Blanco García, Francico J (MDPI, 2024-01-16)
      [Abstract] Osteoarthritis (OA) is a chronic joint disease leading to cartilage loss and reduction in the joint space which results in pain. The current pharmacological treatment of OA is inadequate and pharmacological ...
    • Anti-inflammatory potential of ulvan 

      Flórez-Fernández, Noelia; Rodríguez-Coello, Arianna; Latire, Thomas; Bourgougnon, Natalie; Torres, María Dolores; Buján, Manuela; Muíños, Alexandra; Muíños, Antonio; Meijide-Faílde, Rosa; Blanco García, Francico J; Vaamonde-García, Carlos; Domínguez, Herminia (Elsevier, 2023-12-31)
      [Abstract] Green seaweeds are a widespread group of marine macroalgae that could be regarded as biorenewable source of valuable compounds, in particular sulfated polysaccharides like ulvans with interesting biological ...
    • Exploring the differences between radiographic joint space width and MRI cartilage thickness changes using data from the IMI-APPROACH cohort 

      Jansen, Mylène P.; Roemer, Frank W.; Marijnissen, Anne C.A.; Kloppenburg, Margreet; Blanco García, Francico J; Haugen, Ida K.; Berenbaum, Francis; Lafeber, Floris P.J.G.; Welsing, Paco M.J.; Mastbergen, Simon C.; Wirth, Wolfgang (Springer, 2023-01-06)
      [Abstract] Objective: Longitudinal weight-bearing radiographic joint space width (JSW) and non-weight-bearing MRI-based cartilage thickness changes often show weak correlations. The current objective was to investigate ...
    • Prognostic model to predict the incidence of radiographic knee osteoarthritis 

      Paz-González, Rocío; Balboa-Barreiro, Vanesa; Lourido, Lucía; Calamia, Valentina; Fernández-Puente, Patricia; Oreiro, Natividad; Ruiz-Romero, Cristina; Blanco García, Francico J (BMJ, 2024-01-05)
      [Abstract] Objective: Early diagnosis of knee osteoarthritis (KOA) in asymptomatic stages is essential for the timely management of patients using preventative strategies. We develop and validate a prognostic model useful ...