• RuII(p-cymene) Compounds as Effective and Selective Anticancer Candidates with No Toxicity in Vivo 

      Lenis Rojas, Óscar; Robalo, M. Paula; Tomaz, A. I.; Carvalho, Andreia; Fernandes, Alexandra; Marques, Fernanda; Folgueira, Mónica; Yáñez, Julián; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández Sánchez, Jesús José (American Chemical Society (ACS), 2018-10-19)
      [Abstract] Ruthenium(II) complexes are currently considered a viable alternative to the widely used platinum complexes as efficient anticancer agents. We herein present the synthesis and characterization of half-sandwich ...
    • Pretectal neurons control hunting behaviour 

      Antinucci, Paride; Folgueira, Mónica; Bianco, Isaac H. (eLife Sciences Publications, 2019-10-08)
      [Abstract] For many species, hunting is an innate behaviour that is crucial for survival, yet the circuits that control predatory action sequences are poorly understood. We used larval zebrafish to identify a population ...
    • Comparison of zebrafish and mice knockouts for Megalencephalic Leukoencephalopathy proteins indicates that GlialCAM/MLC1 forms a functional unit 

      Pérez-Rius, Carla; Folgueira, Mónica; Elorza-Vidal, Xabier; Alia, A.; Hoegg-Beiler, Maja B.; Eeza, Muhamed N. H.; Díaz, María Luz; Nunes, Virginia; Barrallo-Gimeno, Alejandro; Estévez, Raúl (BMC, 2019-11-21)
      [Abstract] Background: Megalencephalic Leukoencephalopathy with subcortical Cysts (MLC) is a rare type of leukodystrophy characterized by astrocyte and myelin vacuolization, epilepsy and early-onset macrocephaly. MLC is ...
    • Anatomy and Connectivity of the Torus Longitudinalis of the Adult Zebrafish 

      Folgueira, Mónica; Riva Mendoza, Selva; Ferreño Galmán, María Noelia; Castro, Antonio; Bianco, Isaac H.; Anadón, Ramón; Yáñez, Julián (Frontiers, 2020-03-13)
      [Abstract] This study describes the cytoarchitecture of the torus longitudinalis (TL) in adult zebrafish by using light and electron microscopy, as well as its main connections as revealed by DiI tract tracing. In addition, ...
    • Half-Sandwich Ru(p-cymene) Compounds with Diphosphanes: In Vitro and In Vivo Evaluation As Potential Anticancer Metallodrugs 

      Lenis Rojas, Óscar; Robalo, M. Paula; Tomaz, A. I.; Fernandes, Alexandra; Roma-Rodrigues, Catarina; Teixeira, Ricardo Gonçalves; Marques, Fernanda; Folgueira, Mónica; Yáñez, Julián; Alba-González, Anabel; Salamini-Montemurri, Martín; Pech-Puch, Dawrin; Vázquez, Digna; López-Torres, Margarita; Fernández, Alberto; Fernández Sánchez, Jesús José (American Chemical Society (ACS), 2021-02-11)
      [Abstract] Ruthenium(II) complexes are currently considered attractive alternatives to the widely used platinum-based drugs. We present herein the synthesis and characterization of half-sandwich ruthenium compounds formulated ...
    • The Organization of the Zebrafish Pallium From a Hodological Perspective 

      Yáñez, Julián; Folgueira, Mónica; Lamas Criado, Ibán; Anadón, Ramón (Wiley, 2021-11-11)
      [Abstract] We studied the connections (connectome) of the adult zebrafish pallium using carbocyanine dye tracing and ancillary anatomical methods. The everted zebrafish pallium (dorsal telencephalic area, D) is composed ...
    • A nop56 Zebrafish Loss-of-Function Model Exhibits a Severe Neurodegenerative Phenotype 

      Quelle Regaldie, Ana; Folgueira, Mónica; Yáñez, Julián; Sobrido Cameán, Daniel; Alba-González, Anabel; Barreiro-Iglesias, Antón; Sobrido, María-Jesús; Sánchez Piñón, Laura (MDPI, 2022)
      [Abstract] NOP56 belongs to a C/D box small nucleolar ribonucleoprotein complex that is in charge of cleavage and modification of precursor ribosomal RNAs and assembly of the 60S ribosomal subunit. An intronic expansion ...
    • Distribution of Neurogranin-Like Immunoreactivity in the Brain and Sensory Organs of the Adult Zebrafish 

      Alba-González, Anabel; Folgueira, Mónica; Castro, Antonio; Anadón, Ramón; Yáñez, Julián (Wiley, 2022-01-11)
      [Abstract] We studied the expression of neurogranin in the brain and some sensory organs (barbel taste buds, olfactory organs, and retina) of adult zebrafish. Database analysis shows zebrafish has two paralog neurogranin ...
    • Neurogranin-Like Immunoreactivity in the Zebrafish Brain During Development 

      Alba-González, Anabel; Yáñez, Julián; Anadón, Ramón; Folgueira, Mónica (Springer Nature, 2022-08-26)
      [Abstract] Neurogranin (Nrgn) is a neural protein that is enriched in the cerebral cortex and is involved in synaptic plasticity via its interaction with calmodulin. Recently we reported its expression in the brain of the ...
    • Editorial: Teleostean Forebrain Organization and Evolution: Links to Behavior and Ecological Niche 

      Folgueira, Mónica; Miyasaka, Nobuhiko (Frontiers, 2023-03-07)
    • Severe Neurometabolic Phenotype in NPC1−/− Zebrafish With a C-Terminal Mutation 

      Quelle Regaldie, Ana; Gandoy-Fieiras, Nerea; Villamayor, Paula R.; Maceiras, Sandra; Losada, Ana; Folgueira, Mónica; Cabezas Sáinz, Pablo; Barreiro-Iglesias, Antón; Villar López, María; Quiroga-Berdeal, María Isabel; Sánchez, Laura; Sobrido, María Jesús (Frontiers, 2023-03-17)
      [Abstract] Niemann Pick disease type C (NPC) is an autosomal recessive neurodegenerative lysosomal disorder characterized by an accumulation of lipids in different organs. Clinical manifestations can start at any age and ...
    • Effects of Zinc Oxide Nanoparticle Exposure on Human Glial Cells and Zebrafish Embryos 

      Valdiglesias, Vanessa; Alba-González, Anabel; Fernández-Bertólez, Natalia; Touzani, Assia; Ramos-Pan, Lucía; Reis, Ana Teresa; Moreda-Piñeiro, Jorge; Yáñez, Julián; Laffon, Blanca; Folgueira, Mónica (MDPI, 2023-08-01)
      [Abstract] Zinc oxide nanoparticles (ZnO NPs) are among the most widely used nanomaterials. They have multiple applications in cosmetics, textiles, paints, electronics and, recently, also in biomedicine. This extensive use ...