Gene Signatures Research Involved in Cancer Using Machine Learning
Use this link to citehttp://hdl.handle.net/2183/23937
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TitleGene Signatures Research Involved in Cancer Using Machine Learning
Liñares-Blanco, J.; Fernandez-Lozano, C. Gene Signatures Research Involved in Cancer Using Machine Learning. Proceedings 2019, 21, 19.
[Abstract] With the cheapening of mass sequencing techniques and the rise of computer technologies, capable of analyzing a huge amount of data, it is necessary nowadays that both branches mutually benefit. Transcriptomics, in this case, is a branch of biology focused on the study of mRNA molecules, among others. The quantification of these molecules gives us information about the expression that a gene is having at a given moment. Having information on the expression of the approximately 20,000 genes harbored by human beings is a really useful source of information for the study of certain conditions and/or pathologies. In this work, patient expression -omic data data have been used to offer a new analysis methodology through Machine Learning. The results of this methodology were compared with a conventional methodology to observe how they differed and how they resembled each other. These techniques, therefore, offer a new mechanism for the search of genetic signatures involved, in this case, with cancer.
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