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Peritoneal protein transport during the baseline peritoneal equilibration test is an accurate predictor of the outcome of peritoneal dialysis patients
dc.contributor.author | Pérez-Fontán, Miguel | |
dc.contributor.author | Rodríguez Carmona, Ana | |
dc.contributor.author | Barreda, D. | |
dc.contributor.author | López-Muñiz, Andrés | |
dc.contributor.author | Blanco-Castro, N. | |
dc.contributor.author | García Falcón, María Teresa | |
dc.date.accessioned | 2017-06-27T12:02:20Z | |
dc.date.available | 2017-06-27T12:02:20Z | |
dc.date.issued | 2010 | |
dc.identifier.citation | Pérez-Fontán M, Rodríguez-Carmona A, Barreda D. López-Muñiz A, Blanco-Castro N, García-Falcón T. Peritoneal protein transport during the baseline peritoneal equilibration test is an accurate predictor of the outcome of peritoneal dialysis patients. Nephron Clin Pract. 2010;116(2):104-113 | es_ES |
dc.identifier.issn | 1660-2110 | |
dc.identifier.issn | 1660-8151 | |
dc.identifier.uri | http://hdl.handle.net/2183/19197 | |
dc.description.abstract | [Abstract] Background: Peritoneal protein excretion (PPE) is a potential marker of the outcome in peritoneal dialysis (PD) patients. Method: Observational study of a cohort of 269 patients starting PD in a single unit. Study variables: total PPE during a baseline peritoneal equilibration test (PET; PET-PPE) and 24-hour PPE. Control variables: essential baseline demographic, laboratory and adequacy markers. Main outcomes: mortality, cardiovascular events and risk of peritonitis. We applied univariate and multivariate strategies of survival analysis. Main Results: PET-PPE sustained a significant, yet limited correlation with 24-hour PPE (r = 0.46, p < 0.0005). At baseline, the main study variables showed an independent correlation with peritoneal transport characteristics (D/P240’ creatinine) and cardiovascular comorbidity. PET-PPE (p < 0.0005, model global χ2 59.4) was a more accurate predictor of overall mortality than 24-hour PPE (p = 0.04, χ2 50.5). Moreover, PPE during PET, but not 24-hour PPE, was an independent predictor of the risks of cardiovascular and infectious mortality, and of peritonitis. Conclusions: Baseline PPE represents a strong independent marker of survival of PD patients. Estimation of PPE during PET is more accurate than 24-hour PPE for this purpose, sustains a definite independent association with cardiovascular and infectious mortality, and shows a significant correlation with the risk of peritonitis. | es_ES |
dc.language.iso | eng | es_ES |
dc.publisher | Karger | es_ES |
dc.relation.uri | http://dx.doi.org/10.1159/000314659 | es_ES |
dc.subject | Peritoneal equilibration test | es_ES |
dc.subject | Protein transport | es_ES |
dc.subject | Cardiovascular diseases | es_ES |
dc.subject | Mortality | es_ES |
dc.subject | Peritonitis | es_ES |
dc.title | Peritoneal protein transport during the baseline peritoneal equilibration test is an accurate predictor of the outcome of peritoneal dialysis patients | es_ES |
dc.type | info:eu-repo/semantics/article | es_ES |
dc.rights.access | info:eu-repo/semantics/openAccess | es_ES |
UDC.journalTitle | Nephron Clinical Practice | es_ES |
UDC.volume | 116 | es_ES |
UDC.issue | 2 | es_ES |
UDC.startPage | 104 | es_ES |
UDC.endPage | 113 | es_ES |
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