Listar Grupos de investigación por autor "Paniagua-Martín, María J."
Mostrando ítems 1-20 de 22
-
Chronic anemia in heart transplant patients: prevalence, risk factors, and prognostic significance
Cursack, Guillermo C.; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Naya, Carmen; Grille Cancela, Zulaika; Rodríguez-Fernández, José Ángel; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Ríos, Ramón; Estévez, Francisco; Cuenca, José J.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2007)[Abstract] Introduction and objectives. Data on chronic anemia following heart transplantation (HT) are scarce and contradictory. Our aims were to determine the prevalence of chronic anemia after HT, to identify predisposing ... -
Circulating miR-181a-5p as a New Biomarker for Acute Cellular Rejection in Heart Transplantation
Constanso-Conde, Ignacio; Hermida-Prieto, Manuel; Barge-Caballero, Eduardo; Núñez, Lucía; Pombo-Otero, Jorge; Suárez-Fuentetaja, Natalia; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Pan Lizcano, Ricardo Francisco; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-06-07)[Abstract] Background: Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is ... -
Clinical Profile and Causes of Death According to Ejection Fraction in Patients With Heart Failure Cared for in a Specialized Cardiology Unit
Barge-Caballero, Eduardo; Montero-Fole, B.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Pardo-Martínez, Patricia; Sagastagoitia-Fornie, Marta; Muñiz, Javier; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2021-05-14)[Abstract] Background and objective. Patients with heart failure are classified into three phenotypes based on left ventricular ejection fraction. This work aimed to compare the clinical profile, treatment, prognosis, ... -
Comparison of predicted and observed mortality in patients with heart failure treated at a specialized unit
Barge-Caballero, Eduardo; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Marzoa-Rivas, Raquel; Naya-Leira, Carmen; Riveiro-Rodríguez, Cristina M.; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-01-21)[Abstract] Introduction and objectives: To analyze survival in heart failure (HF) patients treated at a specialized unit. Methods: Prospective cohort-based study of HF patients treated at a specialized unit from 2011 ... -
Gene expression profiling for monitoring graft rejection in heart transplant recipients
Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Hermida-Prieto, Manuel; Castro-Beiras, Alfonso (Elsevier, 2009-08-26)[Abstract] Heart transplantation is a life-prolonging therapy for many patients with stage D heart failure and other forms of advanced heart disease. However, graft rejection and/or immunosuppression-related side effects ... -
Hypotension, acidosis and vasodilation syndrome after heart transplant: incidence, risk factors, and prognosis
Paniagua-Martín, María J.; Crespo-Leiro, María Generosa; Muñiz, Javier; Vázquez, E.; Tabuyo, T.; Castro-Orjales, M.; Fojón, S.; López, J.M.; Garrido, Iris P.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2003-08-30)[Abstract] Background. HAV syndrome, the combination of hypotension, acidosis and vasodilation (HAV), is a serious postoperative complication after heart transplantation (HT). Its etiology and prognosis are poorly ... -
Indoleamine, 2-3 dioxygenase activity could be an early marker of graft rejection in heart transplantation
Suárez-Fuentetaja, Natalia; Doménech, Nieves; Paniagua-Martín, María J.; Marzoa Rivas, Raquel; Barge-Caballero, Eduardo; Grille Cancela, Zulaika; Pombo-Otero, Jorge; Muñiz, Javier; Castro-Beiras, Alfonso; Crespo-Leiro, María Generosa (Elsevier, 2012-11-10)[Abstract] Background. The indoleamine, 2-3 dioxygenase (IDO) is an inducible intracellular enzyme with immunosuppressive effects mainly on lymphocyte populations. It has been postulated that indirect determination of IDO ... -
Long-term results of heart transplant in recipients older and younger than 65 years: a comparative study of mortality, rejections, and neoplasia in a cohort of 445 patients
Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Marzoa Rivas, Raquel; Piñón-Esteban, Pablo; Rodríguez-Fernández, José Ángel; Hermida, L.F.; Calviño-Santos, Ramón; Cuenca, José J.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2005-12-28)[Resumen] Background. Whether being older than 65 years should be considered an absolute counterindication to heart transplant (HT), as it is in some centers, is controversial. In our centre, patients older than 65 years ... -
Lung cancer after heart transplantation: results from a large multicenter registry
Crespo-Leiro, María Generosa; Villa-Arranz, Adolfo; Manito-Lorite, Nicolás; Paniagua-Martín, María J.; Rábago, Gregorio; Almenar-Bonet, Luis; Alonso-Pulpón, Luis; Mirabet, Sonia; Díaz Molina, Beatriz; González-Vílchez, Francisco; Arizón-del-Prado, José M.; Romero-Rodríguez, N.; Delgado-Jiménez, Juan F.; Roig, Eulàlia; Blasco-Peiró, Teresa; Pascual Figal, Domingo A.; De la Fuente-Galán, Luis; Muñiz, Javier (Wiley, 2011-04-26)[Abstract] In this study we analyzed Spanish Post-Heart-Transplant Tumour Registry data for adult heart transplantation (HT) patients since 1984. Median post-HT follow-up of 4357 patients was 6.7 years. Lung cancer (mainly ... -
Microchimerism after heart transplantation: prevalence, predisposing factors, natural history, and prognosis
Crespo-Leiro, María Generosa; Hermida-Prieto, Manuel; Rodríguez-Fernández, José Ángel; Muñiz, Javier; Barral, S.; Paniagua-Martín, María J.; Hermida, L.F.; Juffé-Stein, Alberto; Castro-Beiras, Alfonso (Elsevier, 2002-04-10) -
Paroxysmal bradyarrhythmias are frequent among heart transplant recipients with unexplained syncope: a study based on implantable loop recorders
Martínez-Paz, E.; Barge-Caballero, Eduardo; Álvarez-Roy, Laura; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Mosquera-Pérez, Ignacio; Pérez-Álvarez, Luisa; Muñiz, Javier; Cuenca-Castillo, José J.; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Wiley, 2017-12-13) -
Prevalence and severity of renal dysfunction among 1062 heart transplant patients according to criteria based on serum creatinine and estimated glomerular filtration rate: results from the CAPRI study
Crespo-Leiro, María Generosa; Delgado-Jiménez, Juan F.; Paniagua-Martín, María J.; Vázquez de Prada, José A.; Fernández-Yáñez, Juan; Almenar-Bonet, Luis; Díaz Molina, Beatriz; Roig, Eulàlia; Arizón-del-Prado, José M.; Alonso-Pulpón, Luis; Garrido, Iris P.; Sanz-Julve, Marisa; De la Fuente-Galán, Luis; Mirabet, Sonia; Manito-Lorite, Nicolás; Muñiz, Javier (Wiley, 2009-12-18)[Abstract] Chronic kidney disease (CKD) is staged on the basis of glomerular filtration rate; generally, the MDRD study estimate, eGFR, is used. Renal dysfunction (RD) in heart transplant (HT) patients is often evaluated ... -
Quinolone-related Achilles tendinopathy in heart transplant patients: incidence and risk factors
Barge-Caballero, Eduardo; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Muñiz, Javier; Naya, Carmen; Bouzas-Mosquera, Alberto; Piñón-Esteban, Pablo; Marzoa Rivas, Raquel; Pazos-López, Pablo; Cursack, Guillermo C.; Cuenca-Castillo, José J.; Castro-Beiras, Alfonso (Elsevier, 2008-01-08)[Abstract] Background. A high incidence of Achilles tendinopathy—tendinitis or rupture—has been observed after quinolone treatment in lung and kidney transplant patients. In the absence of relevant published data, we aimed ... -
Real World Comparison of Spironolactone and Eplerenone in Patients With Heart Failure
Pardo-Martínez, Patricia; Barge-Caballero, Eduardo; Bouzas-Mosquera, Alberto; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Sagastagoitia-Fornie, Marta; Prada-Delgado, Óscar; Muñiz, Javier; Almenar-Bonet, Luis; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2022-01-06)[Abstract] Aims. In the absence of previous direct comparative studies, we aimed to evaluate the effectiveness of spironolactone and eplerenone in patients with heart failure and reduced ejection fraction (HFrEF) in a ... -
Renal dysfunction after orthotopic heart transplantation: incidence, natural history, and risk factors
Garrido, Iris P.; Crespo-Leiro, María Generosa; Muñiz, Javier; Rodríguez-Fernández, José Ángel; Regueiro, M.; Vázquez-Rey, E.; Castro-Beiras, Alfonso; Paniagua-Martín, María J. (Elsevier, 2003-08-30)[Abstract] Background. Renal dysfunction is a common complication after orthotopic heart transplantation (HT). The importance of factors other than exposure to immunosuppressive drugs is unclear. The purpose of this study ... -
Risk factors associated with moderate-to-severe renal dysfunction among heart transplant patients: results from the CAPRI study
Delgado-Jiménez, Juan F.; Crespo-Leiro, María Generosa; Gómez-Sánchez, Miguel A.; Paniagua-Martín, María J.; González-Vílchez, Francisco; Vázquez de Prada, José A.; Fernández-Yáñez, Juan; Pascual, David; Almenar-Bonet, Luis; Martínez-Dolz, Luis; Díaz Molina, Beatriz; Roig, Eulàlia; Segovia Cubero, Javier; Arizón-del-Prado, José M.; Garrido, Iris P.; Blasco-Peiró, Teresa; López, Javier; Brossa-Loidi, Vicens; Manito-Lorite, Nicolás; Muñiz, Javier (Wiley, 2010-06-27)[Abstract] The longer survival of patients with heart transplantation (HT) favors calcineurin inhibitor–related chronic kidney disease (CKD). It behoves to identify risk factors. At 14 Spanish centers, data on 1062 adult ... -
Safety of statins when response is carefully monitored: a study of 336 heart recipients
Marzoa Rivas, Raquel; Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Llinares-García, D.; Muñiz, Javier; Aldama López, Guillermo; Piñón-Esteban, Pablo; Campo-Pérez, Rosa; Castro-Beiras, Alfonso (Elsevier, 2005)[Abstract] Background. Statins are used as first-line drugs against hypercholesterolemia after heart transplantation. Randomized clinical trials have shown that they reduce cholesterol levels, and the incidence of rejection ... -
Soluble HLA-G levels in heart transplant recipients: Dynamics and correlation with clinical outcomes
Crespo-Leiro, María Generosa; Grille-Cancela, Zulaika; Barge-Caballero, Eduardo; Doménech, NIeves; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo (Elsevier, 2023)[Abstract] Purpose To describe the evolution of the serum levels of soluble HLA-G (s-HLA-G) during the first 12 months after heart transplantation (HT) and to correlate it with clinical outcomes. Methods Observational ... -
Steroids withdrawal during the first year after heart transplantation and its association with changes in renal function in a two year follow-up. RESTCO study
Crespo-Leiro, María Generosa; Paniagua-Martín, María J.; Gómez-Bueno, Manuel; González-Vílchez, Francisco; Lambert Rodríguez, José Luis; Fernández-Yáñez, Juan; Brossa-Loidi, Vicens; Lage-Gallé, Ernesto; Arizón-del-Prado, José M.; Almenar-Bonet, Luis; Blasco-Peiró, Teresa; De la Fuente-Galán, Luis; Garrido-Bravo, Iris P.; Muñiz, Javier; Delgado-Jiménez, Juan F. (Elsevier, 2014) -
The Falling Incidence of Hematologic Cancer After Heart Transplantation
Crespo-Leiro, María Generosa; Delgado-Jiménez, Juan F.; López, L.; Alonso-Pulpón, Luis; González-Vílchez, Francisco; Almenar-Bonet, Luis; Rábago, Gregorio; Pérez-Villa, Félix; Paniagua-Martín, María J.; Arizón-del-Prado, José M.; Sousa-Casasnovas, Iago; Manito-Lorite, Nicolás; Díaz Molina, Beatriz; Pascual Figal, Domingo A.; Lage-Gallé, Ernesto; Blasco-Peiró, Teresa; De la Fuente-Galán, Luis; Muñiz, Javier (Wiley, 2014-10-01)[Abstract] Background. A number of changes in the management of heart transplantation (HT) patients have each tended to reduce the risk of post-HT hematologic cancer, but little information is available concerning the ...