Browsing Viroloxía clínica by Author "Pedreira, José D."
Now showing items 1-13 of 13
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Any impact of blips and low-level viraemia episodes among HIV-infected patients with sustained virological suppression on ART?
Pernas, Berta; Grandal, Marta; Pértega-Díaz, Sonia; Cañizares, Angelina; Castro-Iglesias, Ángeles; Mena, Álvaro; Rodríguez-Osorio, Iria; Tabernilla, Andrés; Pedreira, José D.; Poveda, Eva (Oxford University Press, 2015-12-24)[Abstract] Objectives. The objective of this study was to evaluate the prevalence of blips and risk of virological failure (VF) among HIV-infected patients with sustained virological suppression (HIV-RNA <50 copies/mL) on ... -
Impact of HCV infection in a HIV cohort followed over18 years: past and present
Mena, Álvaro; Rodríguez-Osorio, Iria; Meijide, Héctor; Castro-Iglesias, Ángeles; López-Calvo, Soledad; Vázquez Rodríguez, Pilar; Pernas, Berta; Grandal, Marta; Pedreira, José D. (Elsevier, 2015-04) -
Increasing incidence of cancer in persons living with HIV coinfected with HCV: an additional impact of HCV infection?
Mena, Álvaro; Meijide, Héctor; Rodríguez-Osorio, Iria; Castro-Iglesias, Ángeles; Pértega-Díaz, Sonia; Rodríguez-Martínez, Guillermo; Pernas, Berta; Baliñas, Josefa; Pedreira, José D.; Poveda, Eva (Elsevier, 2016) -
Liver toxicity and risk of discontinuation in HIV/hepatitis C virus-coinfected patients receiving an etravirine-containing antiretroviral regimen: influence of liver fibrosis
Casado, José Luis; Mena, Álvaro; Bañón, S; Castro-Iglesias, Ángeles; Quereda, C; Moreno, A; Pedreira, José D.; Moreno, S (Wiley, 2015-06-30)[Abstract] Objectives. The aim of the study was to establish the risk of liver toxicity in HIV/hepatitis C virus (HCV)-coinfected patients receiving etravirine, according to the degree of liver fibrosis. Methods. A ... -
Liver-related events and mortality among elderly patients with advanced chronic hepatitis C treated with direct-acting antivirals
Rodríguez-Osorio, Iria; Mena, Álvaro; Meijide, Héctor; Morano, Luis; Delgado, Manuel; Cid-Silva, Purificación; Margusino-Framiñán, Luis; Pedreira, José D.; Castro-Iglesias, Ángeles (Plos ONE, 2019-06-03)[Abstract] BACKGROUND: Direct-acting antivirals (DAAs) are effective in patients aged ≥65 years. However, little is known about the effects of DAAs on survival, liver decompensation and development of hepatocellular ... -
Long-term clinical experience with darunavir (2007–2015) in a large cohort of HIV-infected patients in Spain authors
Pernas, Berta; Grandal, Marta; Tabernilla, Andrés; Cid-Silva, Purificación; Pértega-Díaz, Sonia; Castro-Iglesias, Ángeles; Mena, Álvaro; Margusino-Framiñán, Luis; Pedreira, José D.; Poveda, Eva (Wiley, 2016-06-06)[Abstract] The clinical experience with the protease inhibitor darunavir/ritonavir (DRV/r) was retrospectively evaluated in a cohort of 173 HIV+ patients who initiated antiretroviral treatment including DRV/r (period ... -
Metabolic syndrome association with fibrosis development in chronic hepatitis B virus inactive carriers
Mena, Álvaro; Pedreira, José D.; Castro-Iglesias, Ángeles; López, Soledad; Vázquez-Rodríguez, Pilar; Poveda, Eva (Wiley, 2013-12-19)[Abstract] Background and Aim. There are few data of fibrosis development in chronic hepatitis B (CHB) patients classified as inactive carriers. The aim of this study is to determinate the prevalence of significant fibrosis ... -
Molecular characterization of HIV-1 infection in Northwest Spain (2009–2013): investigation of the subtype F outbreak
Paraskevis, Dimitrios; Kostaki, Evangelia; Beloukas, Apostolos; Cañizares, Angelina; Aguilera, Antonio; Rodríguez, Javier; Grandal, Marta; Pernas, Berta; Castro-Iglesias, Ángeles; Mena, Álvaro; Pedreira, José D.; Poveda, Eva (Elsevier, 2014-12-16)[Abstract] Background. HIV-1 subtype B is the predominant one in European regions several, while other subtypes and recombinants are also circulating with high prevalence. A sub-epidemic of subtype F with specific ... -
Real life experience with direct-acting antivirals agents against hepatitis C infection in elderly patients
Rodríguez-Osorio, Iria; Cid-Silva, Purificación; Morano, Luis; Castro-Iglesias, Ángeles; Suárez, Marta; Delgado, Manuel; Margusino-Framiñán, Luis; Meijide, Héctor; Pernas, Berta; Tabernilla, Andrés; Pedreira, José D.; Mena, Álvaro; Poveda, Eva (Elsevier, 2017-01-18)[Abstract] Background. New direct-acting antivirals agents (DAAs) are very safe and well tolerated. Objectives. The purpose of this study is to analyse the efficacy and safety of DAAs in elderly patients, who have ... -
Seroprevalence of HCV and HIV infections by year of birth in Spain: impact of US CDC and USPSTF recommendations for HCV and HIV testing
Mena, Álvaro; Moldes, Luz; Meijide, Héctor; Cañizares, Angelina; Castro-Iglesias, Ángeles; Delgado, Manuel; Pértega-Díaz, Sonia; Pedreira, José D.; Bou, Germán; Poveda, Eva (PLoS ONE, 2014-12-01) -
Trends in hospital admissions, re-admissions, and in-hospital mortality among HIV-infected patients between 1993 and 2013: impact of hepatitis C co-infection
Meijide, Héctor; Mena, Álvaro; Rodríguez-Osorio, Iria; Pértega-Díaz, Sonia; Castro-Iglesias, Ángeles; Rodríguez-Martínez, Guillermo; Pedreira, José D.; Poveda, Eva (Elsevier, 2017-02-15)[Abstract] Background. New patterns in epidemiological characteristics of people living with HIV infection (PLWH) and the introduction of Highly Active Antiretroviral Therapy (HAART) have changed the profile of hospital ... -
Trends on epidemiological, virological, and clinical features among newly diagnosed HIV-1 persons in Northwest Spain over the last 10 years
Pernas, Berta; Mena, Álvaro; Cañizares, Angelina; Grandal, Marta; Castro-Iglesias, Ángeles; Pértega-Díaz, Sonia; Pedreira, José D.; Poveda, Eva (Wiley, 2015-03-16)[Abstract] To describe temporal trend and characteristics of newly HIV-diagnosed patients in a medical care area in Northwest Spain over the last 10 years. All newly diagnosed patients for HIV-infection from 2004 to 2013 ... -
Update on hepatitis C virus resistance to direct-acting antiviral agents
Poveda, Eva; Wyles, David L.; Mena, Álvaro; Pedreira, José D.; Castro-Iglesias, Ángeles; Cachay, Edward (Elsevier, 2014-06-06)[Abstract] Resistance to direct-acting antiviral (DAA) agents against hepatitis C virus (HCV) infection is driven by the selection of mutations at different positions in the NS3 protease, NS5B polymerase and NS5A proteins. ...
