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Importance of exercise in the control of metabolic and inflammatory parameters at the moment of onset in type 1 diabetic subjects
(Thieme, 2014-05-05)
[Abstract] The onset of type 1 diabetes coincides with the final phase of β-cell destruction. In some cases, this period is characterized by the presence of a functional reserve of β-cells, favouring an adequate metabolic ...
Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism
(Elsevier, 2011)
[Abstract] Ghrelin, a hormone whose levels increase during food deprivation, plays a pivotal role in the regulation of food intake, energy metabolism and storage, as well as in insulin sensitivity. Here, we investigated ...
Changes in hypothalamic expression of the Lin28/let-7 system and related MicroRNAs during postnatal maturation and after experimental manipulations of puberty
(Endocrine Society, 2013)
[Abstract] Lin28 and Lin28b are related RNA-binding proteins that inhibit the maturation of miRNAs of the let-7 family and participate in the control of cellular stemness and early embryonic development. Considerable ...
Circulating levels of irisin in hypopituitary and normal subjects
(PLoS ONE, 2016-07-29)
[Abstract] Context. The recently identified myokine irisin conveys some of the benefits of exercise. Hypopituitarism with adult growth hormone deficiency (HP) is a situation characterized by decreased GH secretion and an ...
Cost-effectiveness analysis of preoperative treatment of acromegaly with somatostatin analogue on surgical outcome
(Elsevier, 2015-08-20)
[Abstract] Context. There is no uniform standard of care for acromegaly. Due to the high costs involved, steps must be taken to ensure the cost-effective delivery of treatment.
Objective. Taking the results of an earlier ...
Effect of cabergoline on tumor remnant after surgery in nonfunctioning pituitary adenoma
(Springer, 2022-11-10)
[Abstract] Background: In recent years, dopamine agonists (DAs) have become an attractive therapeutic option to prevent both tumor growth and post-surgical tumor remnant growth in clinically non-functioning pituitary adenoma ...
Peritoneal total protein transport assessed from peritoneal equilibration tests using different dialysate glucose concentrations
(SAGE, 2010-09)
[Abstract] Background: The peritoneal equilibration test (PET) permits assessment of peritoneal protein transport, but this potential marker of outcome in peritoneal dialysis (PD) patients lacks adequate standardization. ...
Approved and off-label uses of obesity medications, and potential new pharmacologic treatment options
(MDPI, 2010-01-12)
[Abstract] Available anti-obesity pharmacotherapy options remain very limited and development of more effective drugs has become a priority. The potential strategies to achieve weight loss are to reduce energy intake by ...
Bronchial carcinoid and type 1 multiple endocrine neoplasia syndrome: a case report
(Elsevier, 2010-10)
[Abstract] Carcinoid tumours of bronchial origin are rare in type 1 multiple endocrine neoplasia (MEN1) syndrome. The prevalence of histologically confirmed cases is approximately 5-8%, although in more recent studies it ...
Giant non-functioning pituitary adenoma: clinical characteristics and therapeutic outcomes
(Thieme, 2020-01-02)
[Abstract] Background: Giant pituitary adenoma (≥4 cm) is a rare tumor whose clinical features and prognosis are not well known.
Aim: To evaluate the clinical characteristics and therapeutic outcomes of giant non-functioning ...