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Oral glucose-stimulated growth hormone (GH) test in adult GH deficiency patients and controls: potential utility of a novel test
(Elsevier para European Federation of Internal Medicine, 2017-06-09)
[Abstract] Context. The diagnosis of adult GH deficiency requires confirmation with a GH stimulation test. Oral glucose (OG) administration affects GH secretion, initially decreasing and subsequently stimulating GH ...
FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle
(Nature, 2016-07-19)
[Abstract] Irisin is processed from fibronectin type III domain-containing protein 5 (FNDC5). However, a controversy exists concerning irisin origin, regulation and function. To elucidate the relationship between serum ...
Giant non-functioning pituitary adenoma: clinical characteristics and therapeutic outcomes
(Thieme, 2020-01-02)
[Abstract] Background: Giant pituitary adenoma (≥4 cm) is a rare tumor whose clinical features and prognosis are not well known.
Aim: To evaluate the clinical characteristics and therapeutic outcomes of giant non-functioning ...
Craniopharyngioma in the elderly: a multicenter and nationwide study in Spain
(Karger, 2020-10-09)
[Abstract] Background: Craniopharyngioma (CP) is a rare tumor in the elderly whose clinical features and prognosis are not well known in this population. Aim: To evaluate the clinicopathological features and therapeutic ...
Weight-related quality of life in spanish obese subjects suitable for bariatric surgery is lower than in their North American counterparts: a case–control study
(Springer, 2012-10-23)
[Abstract] Background: Obesity impairs quality of life, but the perception of the impairment could be different from one country to another. The purpose was to compare weight-related quality of life (QOL) between cohorts ...
Effect of cabergoline on tumor remnant after surgery in nonfunctioning pituitary adenoma
(Springer, 2022-11-10)
[Abstract] Background: In recent years, dopamine agonists (DAs) have become an attractive therapeutic option to prevent both tumor growth and post-surgical tumor remnant growth in clinically non-functioning pituitary adenoma ...
Approved and off-label uses of obesity medications, and potential new pharmacologic treatment options
(MDPI, 2010-01-12)
[Abstract] Available anti-obesity pharmacotherapy options remain very limited and development of more effective drugs has become a priority. The potential strategies to achieve weight loss are to reduce energy intake by ...
Bronchial carcinoid and type 1 multiple endocrine neoplasia syndrome: a case report
(Elsevier, 2010-10)
[Abstract] Carcinoid tumours of bronchial origin are rare in type 1 multiple endocrine neoplasia (MEN1) syndrome. The prevalence of histologically confirmed cases is approximately 5-8%, although in more recent studies it ...
Pituitary MRI features in acromegaly resulting from ectopic GHRH secretion from a neuroendocrine tumor: analysis of 30 cases
(Oxford University Press on behalf of the Endocrine Society, 2022-05-04)
[Abstract] Context: Ectopic acromegaly is a consequence of rare neuroendocrine tumors (NETs) that secrete GHRH. This abnormal GHRH secretion drives GH and IGF-1 excess, with a clinical presentation similar to classical ...
Executive summary of the consensus document on hypophysitis of the Neuroendocrinology Area of Knowledge of the Spanish Society of Endocrinology and Nutrition
(Elsevier, 2023-03)
[Abstract] The term hypophysitis is used to designate a heterogeneous group of pituitary conditions characterized by the presence of inflammatory infiltration of the adenohypophysis, neurohypophysis, or both. Although ...