• Approved and off-label uses of obesity medications, and potential new pharmacologic treatment options 

      Isidro, María Luisa; Cordido, Fernando (MDPI, 2010-01-12)
      [Abstract] Available anti-obesity pharmacotherapy options remain very limited and development of more effective drugs has become a priority. The potential strategies to achieve weight loss are to reduce energy intake by ...
    • Assessing motivational stages and processes of change for weight management around bariatric surgery: a multicenter study 

      Lecube, Albert; Sánchez, Enric; Andrés, Ana; Saldaña, Carmina; Morales, María José; Calañas, Alfonso; Miñambres, Inka; Pellitero, Silvia; Cordido, Fernando; Bueno, Marta; Caixás, Assumpta; Vilarrasa, Nuria (Springer Nature, 2019-06-17)
      [Abstract] Introduction/purpose: The assessment of the patients' motivation as a predictor of behavioral change via five stages (pre-contemplation, contemplation, preparation, action, and maintenance) and four processes ...
    • Beneficial effects of bariatric surgery-induced by weight loss on the proteome of abdominal subcutaneous adipose tissue 

      Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Varela, Luis; Outeiriño-Blanco, Elena; García-Brao, María Jesús; Mena, Enrique; Noguera, José Francisco; Valero-Gasalla, Javier; Cordido, Fernando; Sangiao-Alvarellos, Susana; Bravo, Susana Belén (MDPI, 2020-01-13)
      [Abstract] Bariatric surgery (BS) is the most effective treatment for obesity and has a positive impact on cardiometabolic risk and in the remission of type 2 diabetes. Following BS, the majority of fat mass is lost from ...
    • Bronchial carcinoid and type 1 multiple endocrine neoplasia syndrome: a case report 

      Montero, Carmen; Sanjuán, Pilar; Fernández, María del Mar; Vidal, Iria; Verea, Héctor; Cordido, Fernando (Elsevier, 2010-10)
      [Abstract] Carcinoid tumours of bronchial origin are rare in type 1 multiple endocrine neoplasia (MEN1) syndrome. The prevalence of histologically confirmed cases is approximately 5-8%, although in more recent studies it ...
    • Central resistance to thyroid hormones in morbidly obese subjects is reversed after bariatric surgery-induced weight loss 

      Juiz-Valiña, Paula; Cordido, María; Outeiriño-Blanco, Elena; Pértega-Díaz, Sonia; Varela-Rodríguez, Bárbara María; García-Brao, María Jesús; Mena, Enrique; Pena-Bello, Lara; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2020-01-28)
      [Abstract] Endocrine abnormalities are common in obesity, including altered thyroid function. The altered thyroid function of obesity may be due to a mild acquired resistance to the thyroid hormone. The aim of this study ...
    • Changes in hypothalamic expression of the Lin28/let-7 system and related MicroRNAs during postnatal maturation and after experimental manipulations of puberty 

      Sangiao-Alvarellos, Susana; Manfredi-Lozano, María; Ruiz-Pino, Francisco; Navarro, V.M.; Sánchez-Garrido, M.A.; León, Silvia; Diéguez, Carlos; Cordido, Fernando; Matagne, V.; Dissen, G.A.; Ojeda, S.R.; Pinilla, Leonor; Tena-Sempere, Manuel (Endocrine Society, 2013)
      [Abstract] Lin28 and Lin28b are related RNA-binding proteins that inhibit the maturation of miRNAs of the let-7 family and participate in the control of cellular stemness and early embryonic development. Considerable ...
    • Circulating levels of irisin in hypopituitary and normal subjects 

      Pena-Bello, Lara; Pértega-Díaz, Sonia; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Eiras-Leal, Raquel; Varela-Rodríguez, Bárbara María; Juiz-Valiña, Paula; Pérez-Fontán, Miguel; Cordido, María; Cordido, Fernando (PLoS ONE, 2016-07-29)
      [Abstract] Context. The recently identified myokine irisin conveys some of the benefits of exercise. Hypopituitarism with adult growth hormone deficiency (HP) is a situation characterized by decreased GH secretion and an ...
    • Clinical significance of T2-weighted sequence intensity on magnetic resonance imaging in clinically non-functioning pituitary adenomas 

      Iglesias, Pedro; Biagetti, Betina; Araújo-Castro, Marta; Alcázar, Victoria; Guerrero-Pérez, Fernando; Riveiro, Noelia; Casteràs, Anna; García Gómez, Carlos; García Izquierdo, Belén; Viedma Torres, Víctor; Pascual-Corrales, Eider; Pavón, Isabel; Villabona, Carles; Cordido, Fernando; Díez, Juan J. (Thieme, 2023-12)
      [Abstract] Background Little is known about the relationship between signal intensity patterns on T2-weighted magnetic resonance imaging (MRI) in non-functioning pituitary adenomas (NFPAs). Objective In this study, the ...
    • Cost-effectiveness analysis of preoperative treatment of acromegaly with somatostatin analogue on surgical outcome 

      Margusino-Framiñán, Luis; Pértega-Díaz, Sonia; Pena-Bello, Lara; Sangiao-Alvarellos, Susana; Outeiriño-Blanco, Elena; Pita-Gutiérrez, Francisco; Pita-Fernández, Salvador; Cordido, Fernando (Elsevier, 2015-08-20)
      [Abstract] Context. There is no uniform standard of care for acromegaly. Due to the high costs involved, steps must be taken to ensure the cost-effective delivery of treatment. Objective. Taking the results of an earlier ...
    • Craniopharyngioma in the elderly: a multicenter and nationwide study in Spain 

      Iglesias, Pedro; Nocete, Ignacio; Moure Rodríguez, María Dolores; Venegas-Moreno, Eva; Ares, Jessica; Biagetti, Betina; Rodríguez Berrocal, Víctor; Guerrero-Pérez, Fernando; Vicente, Almudena; Villar-Taibo, Rocío; Cordido, Fernando; Paja, Miguel; Glerean, Mariela; González Rivera, Natividad; Dios Fuentes, Elena; Blanco, Concepción; Álvarez-Escolá, Crisitina; Martín, Tomás; Webb, Susan M.; Bernabeu, Ignacio; Villabona, Carles; Soto-Moreno, Alfonso; Gaztambide, Sonia; Díez, Juan José (Karger, 2020-10-09)
      [Abstract] Background: Craniopharyngioma (CP) is a rare tumor in the elderly whose clinical features and prognosis are not well known in this population. Aim: To evaluate the clinicopathological features and therapeutic ...
    • Effect of cabergoline on tumor remnant after surgery in nonfunctioning pituitary adenoma 

      Iglesias, Pedro; Biagetti, Betina; Araújo-Castro, Marta; Alcázar, Victoria; Guerrero-Pérez, Fernando; Rivero, Noelia; Casteràs, Anna; García Izquierdo, Belén; García Gómez, Carlos; Viedma Torres, Víctor; Pascual-Corrales, Eider; Pavón, Isabel; Villabona, Carles; Cordido, Fernando; Díez, Juan J. (Springer, 2022-11-10)
      [Abstract] Background: In recent years, dopamine agonists (DAs) have become an attractive therapeutic option to prevent both tumor growth and post-surgical tumor remnant growth in clinically non-functioning pituitary adenoma ...
    • Effect of ghrelin on glucose-insulin homeostasis: therapeutic implications 

      Sangiao-Alvarellos, Susana; Cordido, Fernando (Hindawi, 2010)
      [Abstract] Ghrelin is a 28-amino-acid peptide that displays a strong growth hormone- (GH-) releasing activity through the activation of the growth hormone secretagogue receptor (GHSR). The first studies about role of ghrelin ...
    • Effect of weight loss after bariatric surgery on thyroid-stimulating hormone levels in euthyroid patients with morbid obesity 

      Juiz-Valiña, Paula; Outeiriño-Blanco, Elena; Pértega-Díaz, Sonia; Varela-Rodríguez, Bárbara María; García-Brao, María Jesús; Mena, Enrique; Pena-Bello, Lara; Cordido, María; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2019-05-20)
      [Abstract] Obesity is associated with several endocrine abnormalities, including thyroid dysfunction. The objective of this study was to investigate the effect of weight loss after bariatric surgery on thyroid-stimulating ...
    • Effectiveness of lanreotide autogel 120 mg at extended dosing intervals for acromegaly 

      Bernabéu, Ignacio; Fajardo, Carmen; Marazuela, Mónica; Cordido, Fernando; Venegas, Eva; Pablos Velasco, Pedro de; Piedrola Maroto, Gonzalo; Olvera Márquez, María del Pilar; Pavón de Paz, Isabel; Carvalho, Davide; Romero, Carmen; De la Cruz, Guillermo; Álvarez Escolá, Cristina (Springer, 2020-07-28)
      [Abstract] Purpose. Recent data indicate that extended dosing intervals (EDIs) with lanreotide autogel 120 mg are effective and well-received among patients with acromegaly who have achieved biochemical control with monthly ...
    • Evaluation of thyroid hormone replacement dosing in morbidly obese hypothyroid patients after bariatric surgery-induced weight loss 

      Juiz-Valiña, Paula; Cordido, María; Outeiriño-Blanco, Elena; Pértega-Díaz, Sonia; Urones Cuesta, Paula; García-Brao, María Jesús; Mena, Enrique; Pena-Bello, Lara; Sangiao-Alvarellos, Susana; Cordido, Fernando (MDPI, 2021-08-19)
      [Abstract] The most frequent endocrine disease in obese patients is hypothyroidism. To date, there are no clear data regarding what happens to the dose of levothyroxine (LT4) after bariatric surgery (BS). The objective of ...
    • Executive summary of the consensus document on hypophysitis of the Neuroendocrinology Area of Knowledge of the Spanish Society of Endocrinology and Nutrition 

      Iglesias, Pedro; Biagetti, Betina; Guerrero-Pérez, Fernando; Vicente, Almudena; Cordido, Fernando; Díez, Juan J. (Elsevier, 2023-03)
      [Abstract] The term hypophysitis is used to designate a heterogeneous group of pituitary conditions characterized by the presence of inflammatory infiltration of the adenohypophysis, neurohypophysis, or both. Although ...
    • Factors associated with therapeutic response in acromegaly diagnosed in the elderly in Spain 

      Biagetti, Betina; Iglesias, Pedro; Villar-Taibo, Rocío; Moure, María-Dolores; Paja, Miguel; Araújo-Castro, Marta; Ares, Jessica; Álvarez-Escola, Cristina; Vicente, Almudena; Álvarez Guivernau, Élia; Novoa-Testa, Iria; Guerrero Pérez, Fernando; Cámara, Rosa; Lecumberri, Beatriz; García Gómez, Carlos; Bernabéu, Ignacio; Manjón, Laura; Gaztambide, Sonia; Cordido, Fernando; Webb, Susan; Webb, Susan M.; Menéndez-Torre, Edelmiro Luis; Díez, Juan J.; Simó, Rafael; Puig-Domingo, Manel (Frontiers, 2022-09-16)
      [Abstract] Context: Some reports suggest that acromegaly in elderly patients has a more benign clinical behavior and could have a better response to first-generation long-acting somatostatin receptor ligands (SRL). However, ...
    • FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle 

      Varela-Rodríguez, Bárbara María; Pena-Bello, Lara; Juiz-Valiña, Paula; Vidal Bretal, Beatriz; Cordido, Fernando; Sangiao-Alvarellos, Susana (Nature, 2016-07-19)
      [Abstract] Irisin is processed from fibronectin type III domain-containing protein 5 (FNDC5). However, a controversy exists concerning irisin origin, regulation and function. To elucidate the relationship between serum ...
    • Ghrelin neutralization during fasting-refeeding cycle impairs the recuperation of body weight and alters hepatic energy metabolism 

      Sangiao-Alvarellos, Susana; Helming, Steffen; Vázquez, María J.; Klussmann, Sven; Cordido, Fernando (Elsevier, 2011)
      [Abstract] Ghrelin, a hormone whose levels increase during food deprivation, plays a pivotal role in the regulation of food intake, energy metabolism and storage, as well as in insulin sensitivity. Here, we investigated ...
    • Giant non-functioning pituitary adenoma: clinical characteristics and therapeutic outcomes 

      Iglesias, Pedro; Arcano, Karina; Triviño, Vanessa; Guerrero-Pérez, Fernando; Rodríguez Berrocal, Víctor; Vior, Carlos; Cordido, Fernando; Villabona, Carles; Díez, Juan J. (Thieme, 2020-01-02)
      [Abstract] Background: Giant pituitary adenoma (≥4 cm) is a rare tumor whose clinical features and prognosis are not well known. Aim: To evaluate the clinical characteristics and therapeutic outcomes of giant non-functioning ...