ListarInsuficiencia cardiaca avanzada e transplante cardiaco por tema "Heart transplant"

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    • An integrated molecular diagnostic report for heart transplant biopsies using an ensemble of diagnostic algorithms 

      Parkes, Michael D.; Aliabadi, Arezu Z.; Cadeiras, Martin; Crespo-Leiro, María Generosa; Deng, Mario; Depasquale, Eugene C.; Goekler, Johannes; Kim, Daniel H.; Kobashigawa, Jon; Loupy, Alexandre; Macdonald, Peter; Potena, Luciano; Zuckermann, Andreas; Halloran, Philip F. (Elsevier, 2019-02-06)
      [Abstract] BACKGROUND. We previously reported a microarray-based diagnostic system for heart transplant endomyocardial biopsies (EMBs), using either 3-archetype (3AA) or 4-archetype (4AA) unsupervised algorithms to estimate ...

    • Circulating Galectin-3 Following Heart Transplant: Long-term Dynamics and Prognostic Value 

      Suárez-Fuentetaja, Natalia; Barge-Caballero, Eduardo; Bayés-Genís, Antoni; Doménech, Nieves; Moreda-Santamaría, Lucía; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Estévez-Cid, Francisco; Cuenca-Castillo, José J.; Pombo-Otero, Jorge; Grille-Cancela, Zulaika; Blanco-Canosa, Paula; Muñiz, Javier; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2018-11-23)
      [Abstract] Introduction and objectives: Circulating galectin-3 (Gal-3) is elevated and significantly correlates with all-cause and cardiovascular mortality in patients with heart failure. However, the relationship between ...

    • Clinical usefulness of gene-expression profile to rule out acute rejection after heart transplantation: CARGO II 

      Crespo-Leiro, María Generosa; Stypmann, Jörg; Schulz, Uwe; Zuckermann, Andreas; Mohascsi, Paul; Bara, Christian; Ross, Heather; Parameshwar, Jayan; Zakliczynski, Michal; Fiocchi, Roberto; Hoefer, Daniel; Colvin, Monica; Deng, Mario; Leprince, Pascal; Elashoff, Barbara; Yee, James P.; Vanhaecke, Johan (Oxford University Press en nombre de European Society of Cardiology, 2016-01-07)
      [Abstract] Aims. A non-invasive gene-expression profiling (GEP) test for rejection surveillance of heart transplant recipients originated in the USA. A European-based study, Cardiac Allograft Rejection Gene Expression ...

    • Clinical utility of genetic testing in patients with dilated cardiomyopathy 

      Peña-Peña, María Luisa; Ochoa, Juan Pablo; Barriales-Villa, Roberto; Cicerchia, Marcos; Palomino-Doza, Julián; Salazar-Mendiguchia, Joel; Lamounier, Arsonval; Trujillo, Juan Pablo; García-Giustiniani, Diego; Fernández, Xusto; Ortiz-Genga, Martín; Monserrat, Lorenzo; Crespo-Leiro, María Generosa (Elsevier, 2021-05)
      [Abstract] Introduction and objectives: Dilated cardiomyopathy (DCM) is the most frequent cause of heart transplantation. The prevalence of familial disease can reach 50%. Our objective was to describe the genetic basis ...

    • Cold Ischemia >4 Hours Increases Heart Transplantation Mortality. An Analysis of the Spanish Heart Transplantation Registry 

      Valero-Masa, María Jesús; González-Vílchez, Francisco; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Manito-Lorite, Nicolás; Sobrino-Márquez, José Manuel; Gómez-Bueno, Manuel; Delgado Jiménez, Juan Francisco; Pérez-Villa, Félix; Brossa-Loidi, Vicens; Arizón-del-Prado, José M.; Díaz-Molina, Beatriz; Fuente Galán, Luis de la; Portolés-Ocampo, Ana; Garrido-Bravo, Iris P.; Rábago, Gregorio; Martínez-Sellés, Manuel (Elsevier, 2020-06-20)
      [Abstract] Background. Cold ischemia time (CIT) has been associated to heart transplantation (HT) prognosis. However, there is still uncertainty regarding the CIT cutoff value that might have relevant clinical ...

    • Empleo del balón de contrapulsación intraaórtico como puente al trasplante cardiaco en España: resultados del estudio ASIS-TC 

      Barge-Caballero, Eduardo; González-Vílchez, Francisco; Delgado, Juan F.; Mirabet-Pérez, Sonia; González-Costello, José; Pérez-Villa, Félix; Martínez-Sellés, Manuel; Segovia-Cubero, Javier; Hervás-Sotomayor, Daniela; Blasco-Peiró, Teresa; De la Fuente-Galán, Luis; Garrido-Bravo, Iris P.; Rábago-Juan-Aracil, Gregorio; Muñiz, Javier; Crespo-Leiro, María Generosa (Elsevier, 2018)
      [Resumen] Introducción y objetivos. En España, el balón de contrapulsación intraaórtico (BCIA) se ha usado frecuentemente como puente al trasplante cardiaco (TxC) urgente. El propósito es analizar los resultados de esta ...

    • Impact of Donor-Recipient Age on Cardiac Transplant Survival. Subanalysis of the Spanish Heart Transplant Registry 

      López-Vilella, Raquel; González-Vílchez, Francisco; Crespo-Leiro, María Generosa; Segovia-Cubero, Javier; Cobo, Manuel; Delgado Jiménez, Juan Francisco; Arizón-del-Prado, José M.; Martínez-Sellés, Manuel; Sobrino-Márquez, José Manuel; Mirabet, Sonia; González-Costello, José; Pérez-Villa, Félix; Lambert Rodríguez, José Luis; Rábago, Gregorio; Blasco-Peiró, Teresa; De la Fuente-Galán, Luis; Garrido-Bravo, Iris P.; Otero, Déborah; Almenar-Bonet, Luis (Elsevier, 2020-06-26)
      [Abstract] Introduction and objectives. The age of heart transplant recipients and donors is progressively increasing. It is likely that not all donor-recipient age combinations have the same impact on mortality. The ...

    • Impact of intrapatient blood level variability of calcineurin inhibitors on heart transplant outcomes 

      González-Vílchez, Francisco; Crespo-Leiro, María Generosa; Delgado-Jiménez, Juan F.; Pérez-Villa, Félix; Segovia-Cubero, Javier; Díaz-Molina, Beatriz; Mirabet, Sonia; Arizón-del-Prado, José M.; Blasco-Peiró, Teresa; Martínez-Sellés, Manuel; Almenar-Bonet, Luis; Garrido-Bravo, Iris P.; Rábago, Gregorio; Vázquez de Prada, José A. (Elsevier, 2021-03-18)
      [Abstract] Introduction and objectives. Intrapatient blood level variability (IPV) of calcineurin inhibitors has been associated with poor outcomes in solid-organ transplant, but data for heart transplant are scarce. ...

    • In-Hospital Post-Operative Infection after Heart Transplantation: Epidemiology, Clinical Management, and Outcome 

      Gómez-López, Rocío; Barge-Caballero, Eduardo; Fernández-Ugidos, Paula; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Solla-Buceta, Miguel; Velasco-García de Sierra, Carlos; Aller-Fernández, Vanesa; Fernández-Arias, Laura; Vázquez-Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Mary Ann Liebert, 2020-02-13)
      [Abstract] Background: Infection is a major cause of morbidity and mortality after heart transplantation (HT). Little information about its importance in the immediate post-operative period is available. The aim of this ...

    • Incidence, Risk Factors and Prognostic Impact of Cytomegalovirus Infection After Heart Transplantation 

      Méndez-Eirín, Elizabet; Barge-Caballero, Eduardo; Paniagua-Martín, María J.; Barge-Caballero, Gonzalo; Couto-Mallón, David; Grille Cancela, Zulaika; Blanco-Canosa, Paula; Cañizares-Castellanos, Angelina; González Barbeito, Miguel; Aller Fernández, Ana Vanesa; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier, 2020-03-20)
      [Abstract] Introduction and objectives. To assess the risk factors of CMV infection after heart transplant (HT) and its influence on long-term prognosis. Methods. We conducted a retrospective single-centre study of ...

    • Infectious complications associated with short-term mechanical circulatory support in urgent heart transplant candidates 

      Solla-Buceta, Miguel; González-Vílchez, Francisco; Almenar-Bonet, Luis; Lambert Rodríguez, José Luis; Segovia-Cubero, Javier; González-Costello, José; Delgado-Jiménez, Juan F.; Pérez-Villa, Félix; Crespo-Leiro, María Generosa; Rangel-Sousa, Diego; Martínez-Sellés, Manuel; Rábago, Gregorio; De-la-Fuente Galán, Luis; Blasco-Peiró, Teresa; Hervás-Sotomayor, Daniela; Garrido-Bravo, Iris P.; Mirabet, Sonia; Muñiz, Javier; Barge-Caballero, Eduardo (Elsevier, 2021-02-27)
      [Abstract] Introduction and objectives. Short-term mechanical circulatory support is frequently used as a bridge to heart transplant in Spain. The epidemiology and prognostic impact of infectious complications in these ...

    • Is degree of chronic illness management in heart transplant centers associated with better patient survival?: findings from the intercontinental BRIGHT study 

      Cajita, Maan Isabella; Denhaerynck, Kris; Berben, Lut; Dobbels, Fabienne; Van Cleemput, Johan; Crespo-Leiro, María Generosa; Van Keer, Jan; Poncelet, Alain Jean; Russell, Cynthia; De Geest, Sabina (SAGE, 2021-09-22)
      [Abstract] Purpose: To explore the association between the degree of Chronic illness management and survival rates at 1-, 3-, 5-years post heart transplantation. Methods: Exploratory secondary analysis of a cross-sectional, ...

    • Molecular states associated with dysfunction and graft loss in heart transplants 

      Halloran, Philip F.; Madill-Thomsen, Katelynn; Mackova, Martina; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martin; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Hall, Shelley A.; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas; Reeve, Jeff (Elsevier, 2023-11-30)
      [Abstract] Background: We explored the changes in gene expression correlating with dysfunction and graft failure in endomyocardial biopsies. Methods: Genome-wide microarrays (19,462 genes) were used to define mRNA ...

    • Performance of gene-expression profiling test score variability to predict future clinical events in heart transplant recipients 

      Crespo-Leiro, María Generosa; Stypmann, Jörg; Schulz, Uwe; Zuckermann, Andreas; Mohacsi, Paul; Bara, Christoph; Ross, Heather; Parameshwar, Jayan; Zakliczynski, Michal; Fiocchi, Roberto; Hoefer, Daniel; Deng, Mario; Leprince, Pascal; Hiller, David; Eubank, Emir; Yee, James P.; Vanhaecke, Johan (BioMed Central, 2015-10-09)
      [Abstract] Background. A single non-invasive gene expression profiling (GEP) test (AlloMap®) is often used to discriminate if a heart transplant recipient is at a low risk of acute cellular rejection at time of testing. ...

    • Prognostic value of serum lactate levels in patients undergoing urgent heart transplant: a subanalysis of the ASIS-TC spanish multicenter study 

      Couto-Mallón, David; González-Vílchez, Francisco; Almenar-Bonet, Luis; Díaz-Molina, Beatriz; Segovia-Cubero, Javier; González-Costello, José; Delgado-Jiménez, Juan F.; Castel-Lavilla, María A.; Crespo-Leiro, María Generosa; Rangel-Sousa, Diego; Martínez-Sellés, Manuel; Rábago, Gregorio; De-la-Fuente Galán, Luis; Blasco-Peiró, Teresa; Hervás-Sotomayor, Daniela; Garrido-Bravo, Iris P.; Mirabet, Sonia; Muñiz, Javier; Barge-Caballero, Eduardo (Elsevier, 2018-05-30)
      [Abstract] Introduction and objectives. To study the prognostic value of serum lactate in patients under temporary preoperative mechanical circulatory support who underwent urgent heart transplant. Methods. We conducted ...

    • Prognostic value of the nutritional risk index in heart transplant recipients 

      Barge-Caballero, Eduardo; García-López, Fernando; Marzoa Rivas, Raquel; Barge-Caballero, Gonzalo; Couto-Mallón, David; Paniagua-Martín, María J.; Solla-Buceta, Miguel; Velasco-Sierra, Carlos; Pita-Gutiérrez, Francisco; Herrera-Noreña, José M.; Cuenca-Castillo, José J.; Vázquez Rodríguez, José Manuel; Crespo-Leiro, María Generosa (Elsevier para Sociedad Española de Cardiología, 2017-02-10)
      [Abstract] Introduction and objectives. To study the prognostic impact of preoperative nutritional status, as assessed through the nutritional risk index (NRI), on postoperative outcomes after heart transplantation ...

    • Pulmonary vascular remodeling and prognosis in patients evaluated for heart transplantation: insights from the OCTOPUS-CHF study 

      Martínez-Solano, Jorge; Gutiérrez-Ibañes, Enrique; Ortiz-Bautista, Carlos; García-Cosío, María Dolores; Sarnago-Cebada, Santiago; Díaz-Molina, Beatriz; Pascual, Isaac; Oteo-Domínguez, Juan Francisco; Gómez-Bueno, Manuel; Calviño-Santos, Ramón; Crespo-Leiro, María Generosa; Gómez-Hospital, Joan Antoni; Díez-López, Carles; García-Lara, Juan; Garrido-Bravo, Iris P.; de la Fuente-Galán, Luis; López-Díaz, Javier; Mirabet-Pérez, Sonia; Martínez-Sellés, Manuel (MDPI, 2022-12-06)
      [Abstract] Objective: In patients with advanced heart failure, the intravascular optical coherence tomography (OCT) of subsegmental pulmonary artery measurements is correlated with right heart catheterization parameters. ...

    • Results of heart retransplantation: subanalysis of the Spanish Heart Transplant Registry 

      Salterain-González, Nahikari; Rábago Juan-Aracil, Gregorio; Gómez-Bueno, Manuel; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Arizón del Prado, José María; García-Cosío, María Dolores; Martínez-Sellés, Manuel; Mirabet-Pérez, Sonia; Sobrino-Márquez, José Manuel; González-Costello, José; Pérez-Villa, Félix; Díaz-Molina, Beatriz; de la Fuente-Galán, Luis; Blasco-Peiró, Teresa; Garrido, Iris P.; García-Guereta Silva, Luis; Gil-Villanueva, Nuria; Gran, Ferrán; González-Vilchez, Francisco (Elsevier, 2021-07-10)
      [Abstract] Introduction and objectives: Heart retransplantation (ReHT) is controversial in the current era. The aim of this study was to describe and analyze the results of ReHT in Spain. Methods: We performed a ...

    • Spanish heart transplant registry. 33rd official report of the Heart failure Association of the Spanish Society of Cardiology 

      González-Vílchez, Francisco; Gómez-Bueno, Manuel; Almenar-Bonet, Luis; Crespo-Leiro, María Generosa; Arizón del Prado, José M.; Blázquez-Bermejo, Zorba; Delgado-Jiménez, Juan F.; Antonio-Ferrer, Marta de; Sobrino-Márquez, José M.; García-Romero, Elena (Elsevier, 2022-07-16)
      [Abstract] Introduction and objectives: This report updates the annual data of the Spanish Heart Transplant Registry with the procedures performed in 2021. Methods: We describe the clinical profile, therapeutic ...