ListarInsuficiencia cardiaca avanzada e transplante cardiaco por tema "Gene expression"
Mostrando ítems 1-3 de 3
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Many heart transplant biopsies currently diagnosed as no rejection have mild molecular antibody-mediated rejection-related changes
(Elsevier, 2021-08-04)[Abstract] Background: The Molecular Microscope (MMDx) system classifies heart transplant endomyocardial biopsies as No-rejection (NR), Early-injury, T cell-mediated (TCMR), antibody-mediated (ABMR), mixed, and possible ... -
Molecular states associated with dysfunction and graft loss in heart transplants
(Elsevier, 2023-11-30)[Abstract] Background: We explored the changes in gene expression correlating with dysfunction and graft failure in endomyocardial biopsies. Methods: Genome-wide microarrays (19,462 genes) were used to define mRNA ... -
Redefining the molecular rejection states in 3230 heart transplant biopsies: relationships to parenchymal injury and graft survival
(Elsevier, 2024-03-26)[Abstract] The first-generation Molecular Microscope (MMDx) system for heart transplant endomyocardial biopsies used expression of rejection-associated transcripts (RATs) to diagnose not only T cell-mediated rejection ...