• Indications, complications, and outcomes of cardiac surgery after heart transplantation: results from the cash study 

      Gökler, Johannes; Aliabadi-Zuckermann, Arezu Z.; Kaider, Alexandra; Ambardekar, Amrut V.; Antretter, Herwig; Artemiou, Panagiotis; Bertolotti, Alejandro M.; Boeken, Udo; Brossa, Vicens; Copeland, Hannah; Crespo-Leiro, María Generosa; Eixeré-Esteve, Andrea; Epailly, Eric; Farag, Mina; Hulman, Michal; Khush, Kiran K.; Masetti, Marco; Patel, Jignesh; Ross, Heather J.; Rudez, Igor; Silvestry, Scott; Martín Suárez, Sofía; Vest, Amanda; Zuckermann, Andreas O. (Frontiers, 2022-06-09)
      [Abstract] Background: Allograft pathologies, such as valvular, coronary artery, or aortic disease, may occur early and late after cardiac transplantation. Cardiac surgery after heart transplantation (CASH) may be an option ...
    • Many heart transplant biopsies currently diagnosed as no rejection have mild molecular antibody-mediated rejection-related changes 

      Halloran, Philip F.; Madill-Thomsen, Katelynn; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martín; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas (Elsevier, 2021-08-04)
      [Abstract] Background: The Molecular Microscope (MMDx) system classifies heart transplant endomyocardial biopsies as No-rejection (NR), Early-injury, T cell-mediated (TCMR), antibody-mediated (ABMR), mixed, and possible ...
    • Molecular states associated with dysfunction and graft loss in heart transplants 

      Halloran, Philip F.; Madill-Thomsen, Katelynn; Mackova, Martina; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martin; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Hall, Shelley A.; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas; Reeve, Jeff (Elsevier, 2023-11-30)
      [Abstract] Background: We explored the changes in gene expression correlating with dysfunction and graft failure in endomyocardial biopsies. Methods: Genome-wide microarrays (19,462 genes) were used to define mRNA ...
    • Redefining the molecular rejection states in 3230 heart transplant biopsies: relationships to parenchymal injury and graft survival 

      Halloran, Phillip F.; Madill-Thomsen, Katelynn; Aliabadi-Zuckermann, Arezu Z.; Cadeiras, Martín; Crespo-Leiro, María Generosa; Depasquale, Eugene C.; Deng, Mario; Gökler, Johannes; Hall, Shelley A.; Jamil, Aayla; Kim, Daniel H.; Kobashigawa, Jon; Macdonald, Peter; Melenovsky, Vojtech; Patel, Jignesh; Potena, Luciano; Shah, Keyur; Stehlik, Josef; Zuckermann, Andreas (Elsevier, 2024-03-26)
      [Abstract] The first-generation Molecular Microscope (MMDx) system for heart transplant endomyocardial biopsies used expression of rejection-associated transcripts (RATs) to diagnose not only T cell-mediated rejection ...