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The teaching of rheumatology at the university: the journey from teacher based to student-centered learning
(Elsevier, 2015-07)
[Abstract] In recent years, university education has undergone profound changes as a result of the creation of the European Space for Higher Education. It has gone from a teacher-centred model, based on the transmission ...
Influence of age on rat bone-marrow mesenchymal stem cells potential
(Nature, 2015-11-19)
[Abstract] Mesenchymal stem cells promising role in cell-based therapies and tissue engineering appears to be limited due to a decline of their regenerative potential with increasing donor age. Six age groups from bone ...
Clinical profile, level of affection and therapeutic management of patients with osteoarthritis in primary care: the spanish multicenter study EVALÚA
(Elsevier, 2015-04-16)
[Abstract] Objective. To determine the clinical profile, degree of involvement and management in patients with knee, hip or hand osteoarthritis.
Methods. Observational study (health centres from 14 autonomous regions, n ...
iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis
(BioMed Central, 2015-06-12)
[Abstract]
Introduction. Nuclear accumulation of a mutant form of the nuclear protein Lamin-A, called Progerin (PG) or Lamin AΔ50, occurs in Hutchinson-Gilford Progeria Syndrome (HGPS) or Progeria, an accelerated aging ...