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Human amniotic mesenchymal stromal cells as favorable source for cartilage repair
(Mary Ann Liebert, 2017-01-10)
[Abstract]
Introduction: Localized trauma-derived breakdown of the hyaline articular cartilage may progress toward osteoarthritis, a degenerative condition characterized by total loss of articular cartilage and joint ...
An artificial-vision- and statistical-learning-based method for studying the biodegradation of type I collagen scaffolds in bone regeneration systems
(PeerJ, 2019-07-05)
[Abstract]
This work proposes a method based on image analysis and machine and statistical learning to model and estimate osteocyte growth (in type I collagen scaffolds for bone regeneration systems) and the collagen ...
Molecular profile and cellular characterization of human bone marrow mesenchymal stem cells: donor influence on chondrogenesis
(Elsevier, 2010)
[Abstract] Background. The use of autologous or allogenic stem cells has recently been suggested as an alternative therapeutic approach for treatment of cartilage defects. Bone marrow mesenchymal stem cells (BM-MSCs) are ...
Multilineage differentiation potential of cells isolated from the human amniotic membrane
(Wiley, 2010-11-01)
[Abstract] The human amniotic membrane (HAM) contains two cell types from different embryological origins. Human amnion epithelial cells (hAECs) are derived from the embryonic ectoderm, while human amnion mesenchymal stromal ...
Isolation and characterization of mesenchymal stem cells from human amniotic membrane
(Mary Ann Liebert, 2011-01-04)
[Abstract] Introduction: The human amniotic membrane is a highly abundant and readily available tissue that may be useful for regenerative medicine and cell therapy.
Aim: To compare two previously published protocols for ...
Potential use of the human amniotic membrane as a scaffold in human articular cartilage repair
(Springer, 2010-04-13)
[Abstract] The human amniotic membrane (HAM) is an abundant and readily obtained tissue that may be an important source of scaffold for transplanted chondrocytes in cartilage regeneration in vivo. To evaluate the potential ...
Usefulness of mesenchymal cell lines for bone and cartilage regeneration research
(MDPI, 2019-12-13)
[Abstract]
The unavailability of sufficient numbers of human primary cells is a major roadblock
for in vitro repair of bone and/or cartilage, and for performing disease modelling experiments.
Immortalized mesenchymal ...
Differentiation of human mesenchymal stromal cells cultured on collagen sponges for cartilage repair
(Sociedad Española de Histología e Ingeniería Tisular, 2016)
[Abstract] Aim: The aim of this study was to evaluate proliferation and chondrogenic differentiation of human bone-marrow mesenchymal stromal cells (hBMSCs) cultured on collagen biomaterials.
Materials and methods: ...
Effects of severe hypoxia on bone marrow mesenchymal stem cells differentiation potential
(Hindawi, 2013-06-30)
[Abstract] Background. The interests in mesenchymal stem cells (MSCs) and their application in cell therapy have resulted in a better understanding of the basic biology of these cells. Recently hypoxia has been indicated ...
Alternative protocols to induce chondrogenic differentiation: transforming growth factor-β superfamily
(Springer, 2014-09-10)
[Abstract] Mesenchymal stem cells (MSCs) are an accepted candidate for cell-based therapy of multiple diseases. The interest in MSCs and their possible application in cell therapy have resulted in a better understanding ...