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Human amniotic mesenchymal stromal cells as favorable source for cartilage repair
(Mary Ann Liebert, 2017-01-10)
[Abstract]
Introduction: Localized trauma-derived breakdown of the hyaline articular cartilage may progress toward osteoarthritis, a degenerative condition characterized by total loss of articular cartilage and joint ...
An artificial-vision- and statistical-learning-based method for studying the biodegradation of type I collagen scaffolds in bone regeneration systems
(PeerJ, 2019-07-05)
[Abstract]
This work proposes a method based on image analysis and machine and statistical learning to model and estimate osteocyte growth (in type I collagen scaffolds for bone regeneration systems) and the collagen ...
Molecular profile and cellular characterization of human bone marrow mesenchymal stem cells: donor influence on chondrogenesis
(Elsevier, 2010)
[Abstract] Background. The use of autologous or allogenic stem cells has recently been suggested as an alternative therapeutic approach for treatment of cartilage defects. Bone marrow mesenchymal stem cells (BM-MSCs) are ...
Multilineage differentiation potential of cells isolated from the human amniotic membrane
(Wiley, 2010-11-01)
[Abstract] The human amniotic membrane (HAM) contains two cell types from different embryological origins. Human amnion epithelial cells (hAECs) are derived from the embryonic ectoderm, while human amnion mesenchymal stromal ...
Isolation and characterization of mesenchymal stem cells from human amniotic membrane
(Mary Ann Liebert, 2011-01-04)
[Abstract] Introduction: The human amniotic membrane is a highly abundant and readily available tissue that may be useful for regenerative medicine and cell therapy.
Aim: To compare two previously published protocols for ...
Potential use of the human amniotic membrane as a scaffold in human articular cartilage repair
(Springer, 2010-04-13)
[Abstract] The human amniotic membrane (HAM) is an abundant and readily obtained tissue that may be an important source of scaffold for transplanted chondrocytes in cartilage regeneration in vivo. To evaluate the potential ...
Quantification of cells expressing mesenchymal stem cell markers in healthy and osteoarthritic synovial membranes
(Journal of Rheumatology Publishing Company, 2010-11-15)
[Abstract] Objective. To quantify cells expressing mesenchymal stem cell (MSC) markers in synovial mem- branes from human osteoarthritic (OA) and healthy joints.
Methods. Synovial membranes from OA and healthy joints were ...
Tissue array analysis for the differentiation of gliosis from gliomas
(Spandidos, 2011-03-22)
[Abstract] The aim of this study was to provide a methodology to make a clear distinction between malignant tumors and morphologically similar benign processes, by examining the expression of EGFR, VEGF, HIF1-α, survivin, ...
Usefulness of mesenchymal cell lines for bone and cartilage regeneration research
(MDPI, 2019-12-13)
[Abstract]
The unavailability of sufficient numbers of human primary cells is a major roadblock
for in vitro repair of bone and/or cartilage, and for performing disease modelling experiments.
Immortalized mesenchymal ...
Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes
(BioMed Central, 2012-08-12)
[Abstract]
Background. Osteoarthritis (OA) is a multifactorial disease characterized by destruction of the articular cartilage due to environmental, mechanical and genetic components. The genetics of OA is complex and ...