Now showing items 1-6 of 6

    • Effect of balneotherapy in sulfurous water on an in vivo murine model of osteoarthritis 

      Vaamonde-García, Carlos; Vela Anero, Ángela; Hermida Gómez, Tamara; Burguera, Elena F.; Filgueira-Fernández, P.; Goyanes, Noa; Blanco García, Francisco J; Meijide-Faílde, Rosa (Springer, 2019-11-01)
      [Abstract] Osteoarthritis (OA) is a chronic joint disease that results in progressive cartilage destruction and subsequently joint dysfunction. Growing evidence indicates beneficial impact of balneological interventions ...
    • Effect of hydrogen sulfide sources on inflammation and catabolic markers on interleukin 1β-stimulated human articular chondrocytes 

      Burguera, Elena F.; Vela-Anero, Á.; Magalhaes, J.; Meijide-Faílde, Rosa; Blanco García, Francisco J (Elsevier, 2014-07)
      [Abstract] Objective. Hydrogen sulfide (H2S), the third gasotransmitter together with NO and CO, is emerging as a regulator of inflammation. To test if it might offer therapeutic value in the treatment of osteoarthritis ...
    • Hydrogen sulfide and inflammatory joint diseases 

      Burguera, Elena F.; Meijide-Faílde, Rosa; Blanco García, Francisco J (Bentham, 2017)
      [Abstract] Background: Rheumatoid arthritis (RA) and osteoarthritis (OA) are widespread rheumatic diseases characterized by persistent inflammation and joint destruction. Hydrogen sulfide (H2S) is an endogenous gas with ...
    • Hydrogen sulfide biosynthesis is impaired in the osteoarthritic joint 

      Burguera, Elena F.; Vela Anero, Ángela; Gato Calvo, Lucía; Vaamonde-García, Carlos; Meijide-Faílde, Rosa; Blanco García, Francisco J (Springer, 2019-11-16)
      [Abstract] Osteoarthritis (OA) is the most common form of arthritis and it is a leading cause of disability in the elderly. Its complete etiology is not known although there are several metabolic, genetic, epigenetic, and ...
    • Intraarticular administration effect of hydrogen sulfide on an in vivo rat model of osteoarthritis 

      Vaamonde-García, Carlos; Burguera, Elena F.; Vela-Anero, Á.; Hermida Gómez, Tamara; Filgueira-Fernández, P.; Fernández-Rodríguez, Jennifer Adriana; Meijide-Faílde, Rosa; Blanco García, Francisco J (MDPI, 2020-10-08)
      [Abstract] Osteoarthritis (OA) is the most common articular chronic disease. However, its current treatment is limited and mostly symptomatic. Hydrogen sulfide (H2S) is an endogenous gas with recognized physiological ...
    • Long-term effects of hydrogen sulfide on the anabolic-catabolic balance of articular cartilage in vitro 

      Vela-Anero, Á.; Hermida Gómez, Tamara; Gato Calvo, Lucía; Vaamonde-García, Carlos; Díaz-Prado, Silvia; Meijide-Faílde, Rosa; Blanco García, Francisco J; Burguera, Elena F. (Elsevier, 2017-08-15)
      [Abstract] Healthy cartilage maintenance relies on an equilibrium among the anabolic and catabolic processes in chondrocytes. With the onset of osteoarthritis (OA), increased interleukin (IL)-1β levels induce an inhibition ...