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Gene prioritization, communality analysis, networking and metabolic integrated pathway to better understand breast cancer pathogenesis
(Nature, 2018-11-12)
[Abstract] Consensus strategy was proved to be highly efficient in the recognition of gene-disease association. Therefore, the main objective of this study was to apply theoretical approaches to explore genes and communities ...
OncoOmics approaches to reveal essential genes in breast cancer: a panoramic view from pathogenesis to precision medicine
(Springer Nature, 2020-03-24)
[Abstract]
Breast cancer (BC) is the leading cause of cancer-related death among women and the most commonly diagnosed cancer worldwide. Although in recent years large-scale efforts have focused on identifying new therapeutic ...
Gene Prioritization through Consensus Strategy, Enrichment Methodologies Analysis, and Networking for Osteosarcoma Pathogenesis
(M D P I AG, 2020-02-05)
[Abstract] Osteosarcoma is the most common subtype of primary bone cancer, affecting mostly adolescents. In recent years, several studies have focused on elucidating the molecular mechanisms of this sarcoma; however, its ...
Perturbation-Theory Machine Learning (PTML) Multilabel Model of the ChEMBL Dataset of Preclinical Assays for Antisarcoma Compounds
(American Chemical Society, 2020-10-14)
[Abstract]
Sarcomas are a group of malignant neoplasms of connective tissue with a different etiology than carcinomas. The efforts to discover new drugs with antisarcoma activity have generated large datasets of multiple ...
Prediction of Breast Cancer Proteins Involved in Immunotherapy, Metastasis, and RNA-Binding Using Molecular Descriptors and Artifcial Neural Networks
(Springer Nature, 2020-05-22)
[Abstract]
Breast cancer (BC) is a heterogeneous disease where genomic alterations, protein expression
deregulation, signaling pathway alterations, hormone disruption, ethnicity and environmental
determinants are involved. ...
