Listar GI-RNASA - Artigos por autor "Liñares Blanco, Jose"

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    • A review on machine learning approaches and trends in drug discovery 

      Carracedo-Reboredo, Paula; Liñares Blanco, Jose; Rodríguez-Fernández, Nereida; Cedrón, Francisco; Novoa, Francisco; Carballal, Adrián; Maojo, Víctor; Pazos, A.; Fernández-Lozano, Carlos (Research Network of Computational and Structural Biotechnology, 2021)
      Abstract: Drug discovery aims at finding new compounds with specific chemical properties for the treatment of diseases. In the last years, the approach used in this search presents an important component in computer science ...

    • Machine Learning Algorithms Reveals Country-Specific Metagenomic Taxa from American Gut Project Data 

      Liñares Blanco, Jose; Fernández-Lozano, Carlos; Seoane Fernández, José Antonio; López-Campos, Guillermo (NLM (Medline), 2021)
      [Abstract] In recent years, microbiota has become an increasingly relevant factor for the understanding and potential treatment of diseases. In this work, based on the data reported by the largest study of microbioma in ...

    • Machine learning analysis of TCGA cancer data 

      Liñares Blanco, Jose; Pazos, A.; Fernández-Lozano, Carlos (PeerJ Inc., 2021)
      [Abstract] In recent years, machine learning (ML) researchers have changed their focus towards biological problems that are difficult to analyse with standard approaches. Large initiatives such as The Cancer Genome Atlas ...

    • Machine Learning Analysis of the Human Infant Gut Microbiome Identifies Influential Species in Type 1 Diabetes 

      Fernández-Edreira, Diego; Liñares Blanco, Jose; Fernández-Lozano, Carlos (Elsevier, 2021)
      [Abstract] Diabetes is a disease that is closely linked to genetics and epigenetics, yet mechanisms for clarifying the onset and/or progression of the disease have sometimes not been fully managed. In recent years and due ...

    • Machine Learning Based Microbiome Signature to Predict Inflammatory Bowel Disease Subtypes 

      Liñares Blanco, Jose; Fernández-Lozano, Carlos; Seoane Fernández, José Antonio; López-Campos, Guillermo (FRONTIERS MEDIA S.A., 2022)
      [Abstract] Inflammatory bowel disease (IBD) is a chronic disease with unknown pathophysiological mechanisms. There is evidence of the role of microorganims in this disease development. Thanks to the open access to multiple ...

    • Molecular Docking and Machine Learning Analysis of Abemaciclib in Colon Cancer 

      Liñares Blanco, Jose; Munteanu, Cristian-Robert; Pazos, A.; Fernández-Lozano, Carlos (BioMed Central Ltd., 2020-07-08)
      [Abstract] Background - The main challenge in cancer research is the identification of different omic variables that present a prognostic value and personalised diagnosis for each tumour. The fact that the diagnosis is ...

    • Prediction of high anti-angiogenic activity peptides in silico using a generalized linear model and feature selection 

      Liñares Blanco, Jose; Porto-Pazos, Ana B.; Pazos, A.; Fernández-Lozano, Carlos (Nature, 2018-10-24)
      [Abstract] Screening and in silico modeling are critical activities for the reduction of experimental costs. They also speed up research notably and strengthen the theoretical framework, thus allowing researchers to ...