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A Multi-Objective Approach for Anti-Osteosarcoma Cancer Agents Discovery through Drug Repurposing
(MDPI AG, 2020-11-22)
[Abstract]
Osteosarcoma is the most common type of primary malignant bone tumor. Although nowadays 5-year survival rates can reach up to 60–70%, acute complications and late effects of osteosarcoma therapy are two of the ...
Web Server and R Library for the Calculation of Markov Chains Molecular Descriptors
(MDPI AG, 2020-08-20)
{Abstract]
Markov Chain Molecular Descriptors (MCDs) have been largely used to solve Cheminformatics problems. The software to perform the calculation is not always available for general users. In this work, we developed ...
A review of 28 free animal tracking software: current features and limitations
(Springer Nature, 2021-09)
[Abstract]: Well-quantified laboratory studies can provide a fundamental understanding of animal behavior in ecology, ethology and ecotoxicology research. These types of studies require observation and tracking of each ...
Drugs Repurposing Using QSAR, Docking and Molecular Dynamics for Possible Inhibitors of the SARS-CoV-2 Mpro Protease
(MDPI AG, 2020-11-06)
[Abstract]
Wuhan, China was the epicenter of the first zoonotic transmission of the severe acute respiratory syndrome coronavirus clade 2 (SARS-CoV-2) in December 2019 and it is the causative agent of the novel human ...
Net-Net AutoML Selection of Artificial Neural Network Topology for Brain Connectome Prediction
(MDPI, 2020-02-14)
[Abstract]
Brain Connectome Networks (BCNs) are defined by brain cortex regions (nodes) interacting with others by electrophysiological co-activation (edges). The experimental prediction of new interactions in BCNs ...
Automatic Assessment of Alzheimer’s Disease Diagnosis Based on Deep Learning Techniques
(Elsevier, 2020-05)
[Abstract]
Early detection is crucial to prevent the progression of Alzheimer’s disease (AD). Thus, specialists can begin preventive treatment as soon as possible. They demand fast and precise assessment in the diagnosis ...
Pool-Type FishDesign for a Potamodromous Cyprinid in the Iberian Peninsula: The Iberian Barbel—Synthesis and Future Directions
(M D P I AG, 2020-04-21)
[Abstract] The Iberian barbel (Luciobarbus bocagei) is one of the most common cyprinids in the Iberian Peninsula, whose migratory routes are often hampered by anthropogenic barriers. Fishways might be an effective mitigation ...
Gene Prioritization through Consensus Strategy, Enrichment Methodologies Analysis, and Networking for Osteosarcoma Pathogenesis
(M D P I AG, 2020-02-05)
[Abstract] Osteosarcoma is the most common subtype of primary bone cancer, affecting mostly adolescents. In recent years, several studies have focused on elucidating the molecular mechanisms of this sarcoma; however, its ...
Design and Implementation of a Physical Bitcoin Coin
(MDPI AG, 2020-08-20)
[Abstract]
One of the major factors hindering the adoption of crypto assets in general, and Bitcoin in particular, is the high level of complexity they present to the common user. Although physical coins are a possible ...
A Recommender System Based on Cohorts’ Similarity
(IOS Press, 2020-06-16)
[Abstract]
Aiming to better understand the genetic and environmental associations of Alzheimer's disease, many clinical trials and scientific studies have been conducted. However, these studies are often based on a small ...