Now showing items 6-10 of 28

    • Xylanases From Thermophilic Archaea: A Hidden Treasure 

      Saavedra-Bouza, Almudena; Escuder-Rodríguez, Juan-José; De Castro de Antonio, María Eugenia; Becerra, Manuel; González-Siso, María-Isabel (Elsevier, 2022-12-12)
      [Abstract] Archaea are a domain of prokaryotic organisms that often inhabit extremophilic environments. Their enzymes are therefore of enormous biotechnological interest, due to their stability and activity in harsh ...
    • Study of ferroptosis transmission by small extracellular vesicles in epithelial ovarian cancer cells 

      Alarcón-Veleiro, Carmen; Mato-Basalo, Rocío; Lucio-Gallego, Sergio; Vidal-Pampín, Andrea; Quindós-Varela, María; Al-Qatarneh, Thamer; Berrecoso, Germán; Vizoso-Vázquez, Ángel; Arufe, M.C.; Fafián Labora, Juan Antonio (MDPI, 2023-01-12)
      [Abstract] Epithelial ovarian cancer (EOC) is the most lethal gynecological cancer. The current treatment for EOC involves surgical debulking of the tumors followed by a combination of chemotherapy. While most patients ...
    • Insights on Microbial Communities Inhabiting Non-Volcanic Hot Springs 

      Escuder-Rodríguez, Juan-José; De Castro de Antonio, María Eugenia; Saavedra-Bouza, Almudena; Becerra, Manuel; González-Siso, María-Isabel (MDPI, 2022-10-13)
      [Abstract] The northwest of Spain has an abundance of non-volcanic hot springs that, until recently, had only been used for thermalism activities. One of such hot springs, Muiño da Veiga, has now been explored using ...
    • Role of the E3 Ubiquitin-Ligase Hakai in Intestinal Inflammation and Cancer Bowel Disease 

      Roca-Lema, Daniel; Quiroga, Macarena; Khare, Vineeta; Díaz-Díaz, Andrea; Barreiro-Alonso, Aida; Rodríguez-Alonso, Andrea; Concha, Ángel; Romay, Gabriela; Cerdán, María Esperanza; Gasche, Christoph; Figueroa, Angélica (Springer Nature, 2022-10-20)
      [Abstract] The E3 ubiquitin-ligases are important for cellular protein homeostasis and their deregulation is implicated in cancer. The E3 ubiquitin-ligase Hakai is involved in tumour progression and metastasis, through the ...
    • Reactivity of a Recombinant Esterase from Thermus thermophilus HB27 in Aqueous and Organic Media 

      González González, Roberto; Fuciños, Pablo; Beneventi, Elisa; López-López, Olalla; Pampín, Begoña; Rodríguez, Ramón; González-Siso, María-Isabel; Cruces, Jacobo; Rúa Rodríguez, María Luisa (MDPI, 2022-04-27)
      [Abstract] The thermoalkalophilic membrane-associated esterase E34Tt from Thermus thermophilus HB27 was cloned and expressed in Kluyveromyces lactis (KLEST-3S esterase). The recombinant enzyme was tested as a biocatalyst ...