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Proteomic Analyses Reveal that Sky1 Modulates Apoptosis and Mitophagy in Saccharomyces cerevisiae Cells Exposed to Cisplatin
(Multidisciplinary Digital Publishing Institute, 2014)
[Abstract] Sky1 is the only member of the SR (Serine–Arginine) protein kinase family in Saccharomyces cerevisiae. When yeast cells are treated with the anti-cancer drug cisplatin, Sky1 kinase activity is necessary to produce ...
HMG Proteins from Molecules to Disease [Editorial]
(MDPI, 2022-02-17)
Optimization of Saccharomyces cerevisiae α-galactosidase production and application in the degradation of raffinose family oligosaccharides
(BMC, 2019-10-10)
[Abstract]
Background: α-Galactosidases are enzymes that act on galactosides present in many vegetables, mainly legumes and cereals, have growing importance with respect to our diet. For this reason, the use of their ...
Thermus thermophilus as a Source of Thermostable Lipolytic Enzymes
(Multidisciplinary Digital Publishing Institute, 2015)
Lipolytic enzymes, esterases (EC 3.1.1.1) and lipases (EC 3.1.1.3), catalyze the hydrolysis of ester bonds between alcohols and carboxylic acids, and its formation in organic media. At present, they represent about 20% of ...
Hot Spring Metagenomics
(Multidisciplinary Digital Publishing Institute, 2013)
Hot springs have been investigated since the XIX century, but isolation and examination of their thermophilic microbial inhabitants did not start until the 1950s. Many thermophilic microorganisms and their viruses have ...
The Challenges and Opportunities of lncRNAs in Ovarian Cancer Research and Clinical Use
(MDPI, 2020-04-21)
[Abstract] Ovarian cancer is one of the most lethal gynecological malignancies worldwide because it tends to be detected late, when the disease has already spread, and prognosis is poor. In this review we aim to highlight ...
HMGB1 Protein Interactions in Prostate and Ovary Cancer Models Reveal Links to RNA Processing and Ribosome Biogenesis through NuRD, THOC and Septin Complexes
(MDPI, 2021-09-18)
[Abstract] This study reports the HMGB1 interactomes in prostate and ovary cancer cells lines. Affinity purification coupled to mass spectrometry confirmed that the HMGB1 nuclear interactome is involved in HMGB1 known ...
The HMGB1-2 Ovarian Cancer Interactome: the Role of HMGB Proteins and Their Interacting Partners MIEN1 and NOP53 in Ovary Cancer and Drug-Response
(MDPI, 2020-08-27)
[Abstract] High mobility group box B (HMGB) proteins are overexpressed in different types of cancers such as epithelial ovarian cancers (EOC). We have determined the first interactome of HMGB1 and HMGB2 in epithelial ovarian ...
Thanksgiving to Yeast, the HMGB Proteins History from Yeast to Cancer [Review]
(MDPI, 2023-04-11)
[Abstract] Yeasts have been a part of human life since ancient times in the fermentation of many natural products used for food. In addition, in the 20th century, they became powerful tools to elucidate the functions of ...
Delineating the HMGB1 and HMGB2 Interactome in Prostate and Ovary Epithelial Cells and Its Relationship With Cancer
(Impact Journals, 2018-04-10)
[Abstract] High Mobility Group B (HMGB) proteins are involved in cancer progression and in cellular responses to platinum compounds used in the chemotherapy of prostate and ovary cancer. Here we use affinity purification ...